Search Results - "Damen, Layla"
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A Transcriptomic Signature of the Hypothalamic Response to Fasting and BDNF Deficiency in Prader-Willi Syndrome
Published in Cell reports (Cambridge) (27-03-2018)“…Transcriptional analysis of brain tissue from people with molecularly defined causes of obesity may highlight disease mechanisms and therapeutic targets. We…”
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Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors
Published in Fertility and sterility (01-02-2019)“…To evaluate whether abdominal–pelvic radiotherapy for childhood cancer impairs uterine function and increases the risk of pregnancy complications and adverse…”
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Three years of growth hormone treatment in young adults with Prader-Willi syndrome: sustained positive effects on body composition
Published in Orphanet journal of rare diseases (24-06-2020)“…Abstract Background In children with Prader-Willi syndrome (PWS), the benefits of growth hormone treatment are well established. Several one-year studies have…”
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Improved Mental and Motor Development During 3 Years of GH Treatment in Very Young Children With Prader-Willi Syndrome
Published in The journal of clinical endocrinology and metabolism (01-10-2018)“…Infants and toddlers with Prader-Willi syndrome (PWS) have mental and motor developmental delay. Short-term data suggest a positive effect of GH on mental and…”
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Oxytocin in young children with Prader‐Willi syndrome: Results of a randomized, double‐blind, placebo‐controlled, crossover trial investigating 3 months of oxytocin
Published in Clinical endocrinology (Oxford) (01-05-2021)“…Context Prader‐Willi syndrome (PWS) is characterized by hypothalamic dysfunction, hyperphagia and a typical behavioural phenotype, with characteristics of…”
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Effects of 8 years of growth hormone treatment on scoliosis in children with Prader–Willi syndrome
Published in European journal of endocrinology (21-05-2021)“…Objective Scoliosis is frequently seen in children with Prader–Willi syndrome (PWS). There is still concern that growth hormone (GH) treatment might increase…”
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Bone mineral density during 3 years of growth hormone in previously GH-treated young adults with PWS
Published in European journal of endocrinology (01-06-2021)“…Objective In children with Prader–Willi syndrome (PWS), growth hormone (GH) treatment has positive effects on bone mineral density (BMD). Two 1-year studies…”
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Evidence for Accelerated Biological Aging in Young Adults with Prader–Willi Syndrome
Published in The journal of clinical endocrinology and metabolism (01-06-2020)“…Abstract Objective Adults with Prader–Willi syndrome (PWS) are at increased risk of developing age-associated diseases early in life and, like in premature…”
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Three years of growth hormone treatment in young adults with Prader‐Willi Syndrome previously treated with growth hormone in childhood: Effects on glucose homeostasis and metabolic syndrome
Published in Clinical endocrinology (Oxford) (01-10-2020)“…Context Growth hormone (GH) has been approved for children with Prader‐Willi syndrome (PWS) and significantly improves body composition in adults with PWS…”
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Prevalence of growth hormone (GH) deficiency in previously GH‐treated young adults with Prader‐Willi syndrome
Published in Clinical endocrinology (Oxford) (01-07-2019)“…Objective Some features of subjects with Prader‐Willi syndrome (PWS) resemble those seen in growth hormone deficiency (GHD). Children with PWS are treated with…”
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Long-Term Growth Hormone Treatment of Children with PWS: The Earlier the Start, the Better the Outcomes?
Published in Journal of clinical medicine (29-04-2022)“…Long-term effects of growth hormone (GH) treatment in young children with Prader-Willi syndrome (PWS) have never been compared with untreated age-matched…”
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Prenatal and Neonatal Characteristics of Children with Prader-Willi Syndrome
Published in Journal of clinical medicine (28-01-2022)“…Prader-Willi syndrome (PWS) is a rare genetic syndrome with a wide spectrum of clinical features in early life. Late diagnoses are still present. We…”
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Free Insulin-like Growth Factor (IGF)-I in Children with PWS
Published in Journal of clinical medicine (26-02-2022)“…In children with Prader−Willi syndrome (PWS), the standard growth hormone (GH) dose often results in high immunoreactive IGF-I levels. These high…”
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Effects of Childhood Multidisciplinary Care and Growth Hormone Treatment on Health Problems in Adults with Prader-Willi Syndrome
Published in Journal of clinical medicine (23-07-2021)“…Prader-Willi syndrome (PWS) is a complex hypothalamic disorder. Features of PWS include hyperphagia, hypotonia, intellectual disability, and pituitary hormone…”
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