Search Results - "Dame, Christof"

Prophylactic Early Erythropoietin for Neuroprotection in Preterm Infants: A Meta-analysis by Fischer, Hendrik S, Reibel, Nora J, Bührer, Christoph, Dame, Christof

“…Recombinant human erythropoietin (rhEPO) is a promising pharmacological agent for neuroprotection in neonates. To investigate whether prophylactic rhEPO…”
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Never too late? Quadruplets at the age of 65 years by Hinkson, Larry, Dame, Christof, Braun, Thorsten, Nachtigall, Irit, Henrich, Wolfgang

“…Background We discuss the challenges of multiple pregnancy at very advanced reproductive age. Case presentation We present the case of a quadruplet pregnancy…”
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Response to Letter to the editor on: “Never too late? Quadruplets at the age of 65 years” by Hinkson, Larry, Dame, Christof, Braun, Thorsten, Nachtigall, Irit, Henrich, Wolfgang

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Regulation of clock-controlled genes in mammals by Bozek, Katarzyna, Relógio, Angela, Kielbasa, Szymon M, Heine, Markus, Dame, Christof, Kramer, Achim, Herzel, Hanspeter

“…The complexity of tissue- and day time-specific regulation of thousands of clock-controlled genes (CCGs) suggests that many regulatory mechanisms contribute to…”
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Thrombocytopenia and platelet transfusion in the neonate by Cremer, Malte, Sallmon, Hannes, Kling, Pamela J, Bührer, Christoph, Dame, Christof

“…Summary Neonatal thrombocytopenia is widespread in preterm and term neonates admitted to neonatal intensive care units, with up to one-third of infants…”
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Safety of Early High-Dose Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants by Fauchère, Jean-Claude, MD, Koller, Brigitte M., RN, Tschopp, Alois, PhD, Dame, Christof, MD, Ruegger, Christoph, MD, Bucher, Hans Ulrich, MD

“…Objective To investigate the safety and short term outcome of high dose recombinant human erythropoietin (rhEpo) given shortly after birth and subsequently…”
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Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow by Winter, Oliver, Moser, Katrin, Mohr, Elodie, Zotos, Dimitra, Kaminski, Henriette, Szyska, Martin, Roth, Katrin, Wong, David M., Dame, Christof, Tarlinton, David M., Schulze, Harald, MacLennan, Ian C.M., Manz, Rudolf A.

“…Long-lived plasma cells in the bone marrow produce memory antibodies that provide immune protection persisting for decades after infection or vaccination but…”
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Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation by Rudigier, Lucas J, Dame, Christof, Scholz, Holger, Kirschner, Karin M

“…Gonad morphogenesis relies on the correct spatiotemporal expression of a number of genes that together fulfill the differentiation of the bipotential gonad…”
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The Finnegan Score for Neonatal Opioid Withdrawal Revisited With Routine Electronic Data: Retrospective Study by Rech, Till, Rubarth, Kerstin, Bührer, Christoph, Balzer, Felix, Dame, Christof

“…The severity of neonatal abstinence syndrome (NAS) may be assessed with the Finnegan score (FS). Since the FS is laborious and subjective, alternative ways of…”
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Primary and secondary thrombocytosis in childhood by Dame, Christof, Sutor, Anton Heinz

“…Summary This review summarizes current data on the pathomechanisms and clinical aspects of primary and secondary thrombocytosis in childhood. Primary…”
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Aberrant Hematopoiesis and Morbidity in Extremely Preterm Infants With Intrauterine Growth Restriction by Reibel, Nora J., Dame, Christof, Bührer, Christoph, Muehlbacher, Tobias

“…Background and Objective: Intrauterine growth restriction (IUGR) poses additional challenges in extremely low gestational age newborns (ELGANs). We assessed…”
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Pooling, room temperature, and extended storage time increase the release of adult‐specific biologic response modifiers in platelet concentrates: a hidden transfusion risk for neonates? by Waubert de Puiseau, Miriam, Sciesielski, Lina K., Meyer, Oliver, Liu, Zhi‐Jian, Badur, Chiara‐Aiyleen, Schönfeld, Helge, Tauber, Rudolf, Pruß, Axel, Sola‐Visner, Martha C., Dame, Christof

“…BACKGROUND Adult donor platelets (PLTs) are frequently transfused to prevent or stop bleeding in neonates with thrombocytopenia. There is evidence for PLT…”
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Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update by Fischer, Hendrik S., Reibel, Nora J., Bührer, Christoph, Dame, Christof

“…A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm…”
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Transcription factor Yin-Yang 2 alters neuronal outgrowth in vitro by Klar, Martin, Fenske, Pascal, Vega, Fanny Rezza, Dame, Christof, Bräuer, Anja U

“…The Yin-Yang 2 (YY2) protein is the most recently described member of the family of YY transcription factors. Despite its high structural and functional…”
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Immature Platelet Counts and Thrombopoietin Plasma Concentrations in Thrombocytopenic and Non-thrombocytopenic Preterm Infants by Sallmon, Hannes, Weimann, Andreas, Bührer, Christoph, Metze, Boris, Dame, Christof, Cremer, Malte

“…Objective: Immature platelet counts (IPC) may prove useful in guiding platelet transfusion management in preterm neonates. However, the relationship between…”
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Immature platelet fraction as novel laboratory parameter predicting the course of neonatal thrombocytopenia by Cremer, Malte, Paetzold, Judith, Schmalisch, Gerd, Hammer, Hannes, Loui, Andrea, Dame, Christof, Weimann, Andreas

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Immature platelet values indicate impaired megakaryopoietic activity in neonatal early-onset thrombocytopenia by Cremer, Malte, Weimann, Andreas, Schmalisch, Gerd, Hammer, Hannes, Bührer, Christoph, Dame, Christof

“…Newly released platelets, referred to as immature platelets, can be reliably quantified based on their RNA content by flow cytometry in an automated blood…”
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Mice over-expressing human erythropoietin indicate that erythropoietin enhances expression of its receptor via up-regulated Gata1 and Tal1 by Deindl, Philipp, Klar, Martin, Drews, David, Cremer, Malte, Gammella, Elena, Gassmann, Max, Dame, Christof

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Thrombopoietin Contributes to Neuronal Damage in Experimental Bacterial Meningitis by Hoffmann, Olaf, Rung, Olga, Im, Ae-Rie, Freyer, Dorette, Zhang, Juan, Held, Josephin, Stenzel, Werner, Dame, Christof

“…Thrombopoietin (Tpo), which primarily regulates megakaryopoiesis, and its receptor (c-Mpl) are expressed in the brain, where Tpo exhibits proapototic effects…”
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Transcriptional activity of the novel identified human yy2 promoter is modified by DNA methylation by Klar, Martin, Drews, David, Dame, Christof

“…The recently identified transcription factor YY2 shares important features with the well characterized YY1 zinc finger protein. Both proteins mediate…”
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