Search Results - "Damborsky, J"

The future for the application of fibroblast growth factor 2 in modern wound healing by Holoubek, J., Lipový, B., Knoz, M., Kempný, T., Chaloupková, R., Damborský, J., Vojtová, L.

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Large-scale annotation of biochemically relevant pockets and tunnels in cognate enzyme–ligand complexes by Vavra, O., Tyzack, J., Haddadi, F., Stourac, J., Damborsky, J., Mazurenko, S., Thornton, J. M., Bednar, D.

“…Tunnels in enzymes with buried active sites are key structural features allowing the entry of substrates and the release of products, thus contributing to the…”
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Effects of sex and chronic neonatal nicotine treatment on Na2+ /K+ /Cl− co-transporter 1, K+ /Cl− co-transporter 2, brain-derived neurotrophic factor, NMDA receptor subunit 2A and NMDA receptor subunit 2B mRNA expression in the postnatal rat hippocampus by Damborsky, J.C, Winzer-Serhan, U.H

“…Highlights ► mRNA expression patterns were examined in male and female rat hippocampi at postnatal days 5 and 8. ► The effects of chronic neonatal nicotine…”
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α4β2∗ and α7 nicotinic acetylcholine receptor binding predicts choice preference in two cost benefit decision-making tasks by Mendez, I.A, Damborsky, J.C, Winzer-Serhan, U.H, Bizon, J.L, Setlow, B

“…Highlights ► Examined relationships between decision-making and nicotinic receptor binding. ► Choice of large delayed rewards inversely related to α4β2 binding…”
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OP9: Collagen/Chitosan Dermal Substitute Enriched by Hyperstable FGF2: 4 Years of Development by Knoz, Martin, Lipovy, B., Vojtova, L., Holoubek, J., Zidek, J., Babrnakova, J., Pavlinakova, V., Vistejnova, L., Stepankova, V., Filova, E., Pavlovsky, Z., Faldyna, M., Göpfert, E., Damborsky, J., Hearnden, V.

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Crystal Structure of the Haloalkane Dehalogenase from Sphingomonas paucimobilis UT26 by Marek, Jaromír, Vévodová, Jitka, Smatanová, Ivana Kutá, Nagata, Yuji, Svensson, L. Anders, Newman, Janet, Takagi, Masamichi, Damborský, Jiří

“…The haloalkane dehalogenase from Sphingomonas paucimobilis UT26 (LinB) is the enzyme involved in the degradation of the important environmental pollutant…”
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Analysis of transactivation capability and conformation of p53 temperature-dependent mutants and their reactivation by amifostine in yeast by Grochova, D, Vankova, J, Damborsky, J, Ravcukova, B, Smarda, J, Vojtesek, B, Smardova, J

“…The p53 gene is often mutated during cancer development. Frequency and functional consequences of these mutations vary in different tumor types. We analysed…”
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Atomic resolution studies of haloalkane dehalogenases DhaA04, DhaA14 and DhaA15 with engineered access tunnels by Stsiapanava, A., Dohnalek, J., Gavira, J. A., Kuty, M., Koudelakova, T., Damborsky, J., Kuta Smatanova, I.

“…The haloalkane dehalogenase DhaA from Rhodococcus rhodochrous NCIMB 13064 is a bacterial enzyme that shows catalytic activity for the hydrolytic degradation of…”
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Development of a Crystallization Protocol for the DbeA1 Variant of Novel Haloalkane Dehalogenase from Bradyrhizobium elkani USDA94 by Prudnikova, T., Chaloupkova, R., Sato, Y., Nagata, Y., Degtjarik, O., Kuty, M., Rezacova, P., Damborsky, J., Kuta Smatanova, I.

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Purification and characterization of a haloalkane dehalogenase of a new substrate class from a gamma-hexachlorocyclohexane-degrading bacterium, Sphingomonas paucimobilis UT26 by Nagata, Y, Miyauchi, K, Damborsky, J, Manova, K, Ansorgova, A, Takagi, M

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Analysis of Long Molecular Dynamics Simulations Using Interactive Focus+Context Visualization by Byška, J., Trautner, T., Marques, S.M., Damborský, J., Kozlíková, B., Waldner, M.

“…Analyzing molecular dynamics (MD) simulations is a key aspect to understand protein dynamics and function. With increasing computational power, it is now…”
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Molecular Dissection of Interactions between Rad51 and Members of the Recombination-Repair Group by Krejci, Lumir, Damborsky, Jiri, Thomsen, Bo, Duno, Morten, Bendixen, Christian

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Quantitative structure-function and structure-stability relationships of purposely modified proteins by Damborsky, J.

“…Quantitative structure-function relationships (QSFR) and quantitative structure-stability relationships (QSSR) analyses are described here. The objective of…”
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Analysis of the reaction mechanism and substrate specificity of haloalkane dehalogenases by sequential and structural comparisons by Damborsky, Jiri, Koca, Jaroslav

“…Haloalkane dehalogenases catalyse environmentally important dehalogenation reactions. These microbial enzymes represent objects of interest for protein…”
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Plectin repeats and modules: strategic cysteines and their presumed impact on cytolinker functions by Janda, Lubomír, Damborský, Jiří, Rezniczek, Günther A., Wiche, Gerhard

“…Plectin, a member of the cytolinkers protein family, plays a crucial role in cells as a stabilizing element of cells against mechanical stress. Its absence…”
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TRITON: in silico construction of protein mutants and prediction of their activities by Prokop, Martin, Damborský, Jir̆ı́, Koc̆a, Jaroslav

“…Motivation: One of the objectives of protein engineering is to propose and construct modified proteins with improved activity for the substrate of interest…”
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Dehalogenation of haloalkanes by Mycobacterium tuberculosis H37Rv and other mycobacteria by JESENSKA, A, SEDLACEK, I, DAMBORSKY, J

“…Haloalkane dehalogenases convert haloalkanes to their corresponding alcohols by a hydrolytic mechanism. To date, various haloalkane dehalogenases have been…”
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Identification of the catalytic triad in the haloalkane dehalogenase from Sphingomonas paucimobilis UT26 by Hynková, Kamila, Nagata, Yuji, Takagi, Masamichi, Damborský, Jiřı́

“…The haloalkane dehalogenase from Sphingomonas paucimobilis UT26 (LinB) is the enzyme involved in the γ-hexachlorocyclohexane degradation. This enzyme…”
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Computational site-directed mutagenesis of haloalkane dehalogenase in position 172 by Damborský, J, Bohác, M, Prokop, M, Kutý, M, Koca, J

“…The application of molecular modelling and quantum-chemistry calculations for the 'computational site-directed mutagenesis' of haloalkane dehalogenase is…”
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CaverDock: a molecular docking-based tool to analyse ligand transport through protein tunnels and channels by Vavra, Ondrej, Filipovic, Jiri, Plhak, Jan, Bednar, David, Marques, Sergio M, Brezovsky, Jan, Stourac, Jan, Matyska, Ludek, Damborsky, Jiri

“…Abstract Motivation Protein tunnels and channels are key transport pathways that allow ligands to pass between proteins’ external and internal environments…”
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