Search Results - "Damaso, R"
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Revisiting Jenner's mysteries, the role of the Beaugency lymph in the evolutionary path of ancient smallpox vaccines
Published in The Lancet infectious diseases (01-02-2018)“…In 1796, Edward Jenner developed the smallpox vaccine consisting of pustular material obtained from lesions on cows affected by so-called cow-pox. The disease,…”
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Phasing out monkeypox: mpox is the new name for an old disease
Published in Lancet Regional Health - Americas (Online) (01-01-2023)Get full text
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The 2022 monkeypox outbreak alert: Who is carrying the burden of emerging infectious disease outbreaks?
Published in Lancet Regional Health - Americas (Online) (01-09-2022)Get full text
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Beyond the myths: Novel findings for old paradigms in the history of the smallpox vaccine
Published in PLoS pathogens (01-07-2018)“…In one experiment, Jenner scarified the arm of an 8-year-old boy with the material of a cowpox lesion obtained from the hand of a milkmaid, and 6 weeks later,…”
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Gene duplication, gene loss, and recombination events with variola virus shaped the complex evolutionary path of historical American horsepox-based smallpox vaccines
Published in mBio (31-10-2023)“…Modern smallpox vaccines, such as those used against mpox, are made from vaccinia viruses, but it is still unknown whether cowpox, horsepox, or vaccinia…”
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Re-assembly of nineteenth-century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the USA
Published in Genome Biology (04-12-2020)“…According to a recent article published in Genome Biology, Duggan and coworkers sequenced and partially assembled five genomes of smallpox vaccines from the…”
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Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
Published in Emerging infectious diseases (01-10-2017)“…We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique…”
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Are we there yet? The smallpox research agenda using variola virus
Published in PLoS pathogens (01-05-2014)“… Because of the advances made in the acquisition of knowledge to support diagnostics, antiviral, and vaccine research and development through to the…”
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Genomic diversity of vaccinia virus strain Cantagalo isolated in southeastern Brazil during the early years of the outbreak, 1999-2006
Published in Memórias do Instituto Oswaldo Cruz (01-01-2020)“…Outbreaks of a vesiculopustular disease in dairy cattle and milkers have been frequently reported in Brazil since 1999 when the vaccinia virus strain Cantagalo…”
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Development of standard methods for Zika virus propagation, titration, and purification
Published in Journal of virological methods (01-08-2017)“…•Standard protocols for propagation and titration of Zika virus strains were established.•The susceptibility of different cell types to Zika virus infection…”
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Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis
Published in PLoS neglected tropical diseases (01-06-2019)“…Leishmania parasites are transmitted to vertebrate hosts by phlebotomine sandflies and, in humans, may cause tegumentary or visceral leishmaniasis. The role of…”
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Genomic Characterization of the Historical Smallpox Vaccine Strain Wyeth Isolated from a 1971 Seed Vial
Published in Viruses (28-12-2022)“…The Wyeth strain of vaccinia virus (VACV) produced by Wyeth Pharmaceuticals was supposedly used to manufacture the old freeze-dried American smallpox vaccine,…”
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Evaluation of SARS-CoV-2 ORF7a Deletions from COVID-19-Positive Individuals and Its Impact on Virus Spread in Cell Culture
Published in Viruses (01-03-2023)“…The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the COVID-19 outbreak, posed a primary concern of public health worldwide…”
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Animal movement and establishment of vaccinia virus Cantagalo strain in Amazon biome, Brazil
Published in Emerging infectious diseases (01-04-2011)“…To understand the emergence of vaccinia virus Cantagalo strain in the Amazon biome of Brazil, during 2008-2010 we conducted a molecular and epidemiologic…”
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Potent antiviral activity of brequinar against the emerging Cantagalo virus in cell culture
Published in International journal of antimicrobial agents (01-11-2011)“…Abstract In the present work, the antiviral activity of brequinar (BQR) against the replication of Cantagalo virus was evaluated. BQR is a potent inhibitor of…”
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Biological Characterization and Next-Generation Genome Sequencing of the Unclassified Cotia Virus SPAn232 (Poxviridae)
Published in Journal of Virology (01-05-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Searching for the origin of the smallpox vaccine: Edward Jenner and his little-known horsepox hypothesis
Published in Vaccine (03-01-2022)“…[...]Jenner’s failure to obtain experimental evidence could be another explanation for not having pursued with more persistence his horsepox hypothesis. Loy’s…”
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Swinepox virus outbreak, Brazil, 2011
Published in Emerging infectious diseases (01-10-2011)Get full text
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Equination (inoculation of horsepox): An early alternative to vaccination (inoculation of cowpox) and the potential role of horsepox virus in the origin of the smallpox vaccine
Published in Vaccine (19-12-2017)“…For almost 150 years after Edward Jenner had published the “Inquiry” in 1798, it was generally assumed that the cowpox virus was the vaccine against smallpox…”
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Endotoxin levels correlate positively with a sedentary lifestyle and negatively with highly trained subjects
Published in Lipids in health and disease (04-08-2010)“…A sedentary lifestyle increases the risk of developing cardiovascular disease, obesity, and diabetes. This phenomenon is supported by recent studies suggesting…”
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