Search Results - "Dam, Tomas Norman"
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Interleukin-20 as a Target in Psoriasis Treatment
Published in Annals of the New York Academy of Sciences (01-09-2007)“…: Interleukin‐20 (IL‐20) is a new member of the IL‐10 cytokine family discovered by a structural algorithm. IL‐20 transgenic mice displayed skin abnormalities…”
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Predictors of Response to Biologics in Patients with Moderate-to-severe Psoriasis: A Danish Nationwide Cohort Study
Published in Acta dermato-venereologica (26-10-2021)“…Identifying patient characteristics associated withachieving treatment response to biologics in patients with psoriasis could prevent expensive switching…”
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Medical specialists' use and opinion of video consultation in Denmark: a survey study
Published in BMC health services research (24-04-2024)“…The COVID-19 pandemic accelerated the use of telemedicine which is seen as a possibility to reduce the pressure on healthcare systems globally. However, little…”
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Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis
Published in PloS one (01-02-2018)“…Psoriasis (PsO) is a chronic inflammatory disease with predominantly cutaneous manifestations. Approximately one third of patients with PsO develop psoriatic…”
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Patient-reported Outcomes During Treatment in Patients with Moderate-to-severe Psoriasis: A Danish Nationwide Study
Published in Acta dermato-venereologica (01-12-2019)“…The initiation and evaluation of treatment with biologics for psoriasis is based on the Psoriasis Area Severity Index (PASI) and/or Dermatological Life Quality…”
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Response to Biologics During the First Six Months of Therapy in Biologic-naïve Patients with Psoriasis Predicts Risk of Disease Flares: A Danish Nationwide Study
Published in Acta dermato-venereologica (01-01-2021)“…Early response to treatment with biologics might be important for the stability of psoriasis and long-term outcome. The aim of this study was therefore to…”
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Pharmacological undertreatment of coronary risk factors in patients with psoriasis: observational study of the Danish nationwide registries
Published in PloS one (30-04-2012)“…Patients with psoriasis have increased prevalence of coronary risk factors and limited recent results have suggested that these risk factors are undertreated…”
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Valrubicin in a Topical Formulation Treats Psoriasis in a Xenograft Transplantation Model
Published in Journal of investigative dermatology (01-02-2010)“…Valrubicin is a cytostatic drug currently approved by the American Federal Drug Administration as a trademarked Valstar sterile solution for the treatment of…”
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Statistical evaluation and experimental design of a psoriasis xenograft transplantation model treated with cyclosporin A
Published in Experimental dermatology (01-05-2011)“…: Psoriasis xenograft transplantation models where human skin is transplanted onto immune‐deficient mice are generally accepted in psoriasis research. Over…”
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Application of stereology to dermatological research
Published in Experimental dermatology (01-12-2009)“…: Stereology is a set of mathematical and statistical tools to estimate three‐dimensional (3‐D) characteristics of objects from regular two‐dimensional (2‐D)…”
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Pan-selectin antagonism improves psoriasis manifestation in mice and man
Published in Archives of Dermatological Research (01-02-2006)“…The selectin family of vascular cell adhesion molecules is comprised of structurally related carbohydrate binding proteins, which mediate the initial rolling…”
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Outcomes Following a Mandatory Nonmedical Switch From Adalimumab Originator to Adalimumab Biosimilars in Patients With Psoriasis
Published in JAMA dermatology (Chicago, Ill.) (01-06-2021)“…The efficacy of adalimumab biosimilars is similar to that of brand-name adalimumab (Humira, hereinafter originator) in clinical trials. However, limited…”
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Debio 0932, a new oral Hsp90 inhibitor, alleviates psoriasis in a xenograft transplantation model
Published in Acta dermato-venereologica (01-01-2014)“…Debio 0932 is a novel oral heat shock protein 90 (Hsp90) inhibitor developed for anti-cancer therapy. Surprising-ly, during the first clinical trial, one…”
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Valrubicin activates PKCa in keratinocytes: a conceivable mode of action in treating hyper-proliferative skin diseases
Published in Journal of drugs in dermatology (01-10-2013)“…Valrubicin is a semisynthetic anthracycline developed as an anti-cancer drug able to ameliorate psoriasis and non-melanoma skin cancer (NMSC) by topical…”
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The Danish Nonmelanoma Skin Cancer Dermatology Database
Published in Clinical epidemiology (01-01-2016)“…The Danish Nonmelanoma Skin Cancer Dermatology Database was established in 2008. The aim of this database was to collect data on nonmelanoma skin cancer (NMSC)…”
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Interleukin-20--a new target in psoriasis treatment
Published in Ugeskrift for læger (01-09-2008)“…Interleukin-20 (IL-20) is suggested as a new target in psoriasis treatment. It was first described in 2001, and the potential role of this cytokine in…”
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1α,25-Dihydroxycholecalciferol and Cyclosporine Suppress Induction and Promote Resolution of Psoriasis in Human Skin Grafts Transplanted on to SCID Mice
Published in Journal of investigative dermatology (01-12-1999)“…Accumulating evidence has emphasized the importance of immunocompetent cells in determining the psoriatic phenotype. We have investigated the effect of…”
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