Search Results - "Daly, J. W"

Caffeine analogs: biomedical impact by Daly, J. W

“…Caffeine, widely consumed in beverages, and many xanthine analogs have had a major impact on biomedical research. Caffeine and various analogs, the latter…”
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Batrachotoxin Alkaloids from Passerine Birds: A Second Toxic Bird Genus (Ifrita kowaldi) from New Guinea by Dumbacher, J. P., Spande, T. F., Daly, J. W.

“…Batrachotoxins, including many congeners not previously described, were detected, and relative amounts were measured by using HPLC-mass spectrometry, in five…”
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Epibatidine, a potent analgetic and nicotinic agonist by Badio, B, Daly, J W

“…Synthetic (+)- and (-)-epibatidine (an alkaloid originally characterized from frog skin) have potent analgetic activity in mice, using the hot-plate assay. The…”
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Alkaloids in Bufonid Toads (Melanophryniscus): Temporal and Geographic Determinants for Two Argentinian Species by Daly, J. W, Wilham, J. M, Spande, T. F, Garraffo, H. M, Gil, R. R, Silva, G. L, Vaira, M

“…Bufonid toads of the genus Melanophryniscus represent one of several lineages of anurans with the ability to sequester alkaloids from dietary arthropods for…”
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A unified framework for coupling measurement in object-oriented systems by Briand, L.C., Daly, J.W., Wust, J.K.

“…The increasing importance being placed on software measurement has led to an increased amount of research developing new software measures. Given the…”
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Evidence for Biosynthesis of Pseudophrynamine Alkaloids by an Australian Myobatrachid Frog (Pseudophryne) and for Sequestration of Dietary Pumiliotoxins by Smith, B. P, Tyler, M. J, Kaneko, T, Garraffo, H. M, Spande, T. F, Daly, J. W

“…Australian myobatrachid frogs of the genus Pseudophryne have only two classes of alkaloids in skin extracts, pseudophrynamines (PSs) and pumiliotoxins (PTXs)…”
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Thirty Years of Discovering Arthropod Alkaloids in Amphibian Skin by Daly, John William

“…Amphibian skin has provided a wide range of biologically active alkaloids. During the past 30 years, over 400 alkaloids of over 20 structural classes have been…”
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The Chemistry of Poisons in Amphibian Skin by Daly, John W.

“…Poisons are common in nature, where they often serve the organism in chemical defense. Such poisons either are produced de novo or are sequestered from dietary…”
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A siphonotid millipede (Rhinotus) as the source of spiropyrrolizidine oximes of dendrobatid frogs by SAPORITO, R. A, DONNELLY, M. A, HOFFMAN, R. L, GARRAFFO, H. M, DALY, J. W

“…Poison frogs of the neotropical family Dendrobatidae contain a wide variety of lipophilic alkaloids, which are accumulated from alkaloid-containing arthropods…”
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Alkaloids from Amphibian Skin:  A Tabulation of Over Eight-Hundred Compounds by Daly, John W, Spande, Thomas F, Garraffo, H. Martin

“…A diverse array of biologically active, lipid-soluble alkaloids have been discovered in amphibian skin. Such alkaloids include the following:  the steroidal…”
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Tumor proliferation in rectal cancer following preoperative irradiation by Willett, C G, Warland, G, Hagan, M P, Daly, W J, Coen, J, Shellito, P C, Compton, C C

“…This study examines the effect of preoperative irradiation on tumor proliferation in rectal cancer. One hundred twenty-two patients with locally advanced…”
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Loperamide: novel effects on capacitative calcium influx by Daly, J W, Harper, J

“…Loperamide is a widely used antidiarrheal that primarily acts at nanomolar concentrations through activation of opioid receptors in the gastrointestinal tract…”
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Clinical pharmacology in the Middle Ages: Principles that presage the 21st century by Brater, D. Craig, Daly, Walter J.

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A Stereospecific Synthesis of (±)-5,8-Disubstituted Indolizidines and (±)-1,4-Disubstituted Quinolizidines Found in Poison Frog Skins by Michel, Patrick, Rassat, André, Daly, John W, Spande, Thomas F

“…An efficient, high-yield stereospecific route to three (±)-5,8-disubstituted indolizidines, (209B ( I ), 209I ( II ), 223J ( III )) and two…”
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Primary squamous cell carcinoma of the ovary : Report of 37 cases by PINS, M. R, YOUNG, R. H, DALY, W. J, SCULLY, R. E

“…A total of 37 cases of ovarian primary squamous cell carcinoma (SCC)-19 associated with a dermoid cyst (SCCD), seven associated with endometriosis (SCCE), and…”
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The impact of 5-fluorouracil and intraoperative electron beam radiation therapy on the outcome of patients with locally advanced primary rectal and rectosigmoid cancer by NAKFOOR, B. M, WILLETT, C. G, SHELLITO, P. C, KAUFMAN, D. S, DALY, W. J

“…To analyze the effects of 5-fluorouracil (5-FU) chemotherapy combined with preoperative irradiation and the role of intraoperative electron beam irradiation…”
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Arthropod-frog connection : Decahydroquinoline and pyrrolizidine alkaloids common to microsympatric myrmicine ants and dendrobatid frogs by DALY, J. W, GARRAFFO, H. M, JAIN, P, SPANDE, T. F, SNELLING, R. R, JARAMILLO, C, RAND, A. S

“…Neotropical poison frogs (Dendrobatidae) contain a wide variety of lipophilic alkaloids, apparently accumulated unchanged into skin glands from dietary…”
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Further alkaloids common to ants and frogs: decahydroquinolines and a quinolizidine by Jones, T.H, Gorman, J.S.T, Snelling, R.R, Delabie, J.H.C, Blum, M.S, Garraffo, H.M, Jain, P, Daly, J.W, Spande, T.F

“…Three alkaloids--two minor decahydroquinolines (DHQs) and a major quinolizidine--were detected in an extract of a Brazilian myrmicine ant (Solenopsis…”
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Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine by Badio, Barbara, Garraffo, H.Martin, Plummer, Carlton V, Padgett, William L, Daly, John W

“…Synthetic (±)-epiboxidine (exo-2-(3-methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane) is a methylisoxazole analog of the alkaloid epibatidine, itself a potent…”
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Alkaloids from Bufonid Toads (Melanophryniscus): Decahydroquinolines, Pumiliotoxins and Homopumiliotoxins, Indolizidines, Pyrrolizidines, and Quinolizidines by Garraffo, H. M, Spande, T. F, Daly, J. W, Baldessari, A, Gros, E. G

“…Skins of bufonid toads of the genus Melanophryniscus contain several classes of alkaloids: decahydroquinolines, pumiliotoxins, allopumiliotoxins,…”
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