Search Results - "Dalvi, Prasad S"
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Long-term metabolic effects of malnutrition: Liver steatosis and insulin resistance following early-life protein restriction
Published in PloS one (02-07-2018)“…Early postnatal-life malnutrition remains prevalent globally, and about 45% of all child deaths are linked to malnutrition. It is not clear whether survivors…”
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Glucagon-Like Peptide-1 Receptor Agonist, Exendin-4, Regulates Feeding-Associated Neuropeptides in Hypothalamic Neurons in Vivo and in Vitro
Published in Endocrinology (Philadelphia) (01-05-2012)“…Exendin-4, a long-acting glucagon-like peptide-1 receptor (GLP-1R) agonist, is a potential regulator of feeding behavior through its ability to inhibit gastric…”
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3
Carbohydrate malabsorption in acutely malnourished children and infants: a systematic review
Published in Nutrition reviews (01-01-2016)“…Context: Severe acute malnutrition (SAM) accounts for approximately 1 million child deaths per year. High mortality is linked with comorbidities, such as…”
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Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK
Published in Journal of vascular research (01-11-2020)“…We have shown that both insulin and resveratrol (RSV) decrease neointimal hyperplasia in chow-fed rodents via mechanisms that are in part overlapping and…”
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Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
Published in The FASEB journal (01-12-2009)“…The distinct lack of cell lines derived from the adult brain is evident. Ciliary neurotrophic factor (CNTF) triggers neurogenesis in primary culture from adult…”
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The cytokine ciliary neurotrophic factor (CNTF) activates hypothalamic urocortin-expressing neurons both in vitro and in vivo
Published in PloS one (23-04-2013)“…Ciliary neurotrophic factor (CNTF) induces neurogenesis, reduces feeding, and induces weight loss. However, the central mechanisms by which CNTF acts are…”
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Insulin signalling in hypothalamic neurones
Published in Journal of neuroendocrinology (01-04-2021)“…Subsequent to the discovery of insulin by Banting and Best in the Department of Physiology at the University of Toronto 100 years ago, the field of insulin…”
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Regulation of brain insulin mRNA by glucose and glucagon-like peptide 1
Published in Biochemical and biophysical research communications (28-11-2008)“…Whether the brain synthesizes insulin is currently debated. Two clonal, immortalized mouse hypothalamic cell lines from e17, mHypoE-39 and mHypoE-46, express…”
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Divergent Regulation of ER and Kiss Genes by 17β-Estradiol in Hypothalamic ARC Versus AVPV Models
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2016)“…Kisspeptin (Kiss) and G-protein-coupled receptor (Gpr)54 have emerged as key regulators of reproduction. 17β-estradiol (E2)-mediated regulation of these…”
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Hypothalamic miR-1983 Targets Insulin Receptor β and the Insulin-mediated miR-1983 Increase Is Blocked by Metformin
Published in Endocrinology (Philadelphia) (01-01-2022)“…MicroRNAs (miRNAs) expressed in the hypothalamus are capable of regulating energy balance and peripheral metabolism by inhibiting translation of target…”
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DJ-1 and Parkinson's disease
Published in Brain disorders (01-09-2021)“…•Parkinson's disease occurs through degeneration of neurons of substantia niagra and the nigrostriatal pathway.•Accumulation of oxidative stress is likely a…”
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Glucagon-Like Peptide-2 Directly Regulates Hypothalamic Neurons Expressing Neuropeptides Linked to Appetite Control in Vivo and in Vitro
Published in Endocrinology (Philadelphia) (01-05-2012)“…Glucagon-like peptide-2 (GLP-2), a proglucagon-derived peptide, has been postulated to affect appetite at the level of the hypothalamus. To gain better insight…”
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13
Immortalized neurons for the study of hypothalamic function
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-05-2011)“…The hypothalamus is a vital part of the central nervous system: it harbors control systems implicated in regulation of a wide range of homeostatic processes,…”
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14
Immunofluorescence of GFAP and TNF-α in the Mouse Hypothalamus
Published in Bio-protocol (05-07-2021)“…Immunofluorescence is a reliable method for identifying specific proteins in neuronal and glial cell populations of the hypothalamus. Several…”
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Metabolomics in plasma of Malawian children 7 years after surviving severe acute malnutrition: “ChroSAM” a cohort study
Published in EBioMedicine (01-07-2019)“…More children are now surviving severe acute malnutrition (SAM), but evidence suggests that early-life malnutrition is associated with increased risk of…”
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The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent
Published in Atherosclerosis (01-07-2015)“…Abstract In vitro , insulin has mitogenic effects on vascular smooth muscle cells (VSMC) but also has protective effects on endothelial cells by stimulating…”
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The impact of diabetes mellitus on the development of psychiatric and neurological disorders
Published in Brain disorders (01-06-2024)“…•Diabetes mellitus affects several organ systems and bodily mechanisms with its hallmark pathology of insulin deficiency/resistance, hyperglycemia, and…”
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A case report: An aortobifemoral bypass implant found during cadaver dissection promotes inquiry-based learning
Published in International journal of surgery case reports (01-01-2020)“…•An unusual case of peripheral arterial disease with an aortobifemoral bypass graft.•Aortobifemoral bypass grafts preserve flow to the lower…”
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Direct Regulation of the Proglucagon Gene by Insulin, Leptin, and cAMP in Embryonic versus Adult Hypothalamic Neurons
Published in Molecular endocrinology (Baltimore, Md.) (01-08-2012)“…The proglucagon gene is expressed not only in the pancreas and intestine but also in the hypothalamus. Proglucagon-derived peptides have emerged as potential…”
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Potentiation of the hepatic toxicity of carbon disulfide by chlordane
Published in Toxicology international (01-05-2013)“…Objectives: In this study, we investigated whether cytochrome P450s (CYPs) induced by a typical chlorinated hydrocarbon insecticide chlordane (CLD) potentiate…”
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