Search Results - "Dalton, Robert"
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Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice
Published in PloS one (10-01-2019)“…Prg4, also known as Lubricin, acts as a joint/boundary lubricant. Prg4 has been used to prevent surgically induced osteoarthritis (OA) in mice. Surgically…”
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Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes
Published in International journal of molecular sciences (15-02-2023)“…Myelodysplastic Syndromes (MDSs) are bone marrow (BM) failure malignancies characterized by constitutive innate immune activation, including NLRP3 inflammasome…”
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Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013
Published in Mayo Clinic proceedings (01-04-2013)“…Abstract Multiple myeloma remains an incurable neoplasm of plasma cells that affects more than 20,000 people annually in the United States. There has been a…”
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On-Premise Signage and Placemaking: Aiding Lively Streetscapes to Maintain Signage Visibility
Published in Interdisciplinary journal of signage and wayfinding (20-12-2023)“…Placemaking is an initiative with roots in the 1960s and 70s to enhance public life in the urban setting. This complex notion requires multiple disciplines,…”
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Tissue-engineered blood vessel mimics in complex geometries for intravascular device testing
Published in PloS one (26-06-2019)“…Intravascular stents are commonly used to treat occluded arteries during coronary heart disease. After coronary stent implantation, endothelial cells grow over…”
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Splicing in a single neuron is coordinately controlled by RNA binding proteins and transcription factors
Published in eLife (19-07-2019)“…Single-cell transcriptomes are established by transcription factors (TFs), which determine a cell's gene-expression complement. Post-transcriptional regulation…”
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Constitutively Activated DAP12 Induces Functional Anti-Tumor Activation and Maturation of Human Monocyte-Derived DC
Published in International journal of molecular sciences (27-01-2021)“…Dendritic cells (DCs) are professional antigen presenting cells with a great capacity for cross-presentation of exogenous antigens from which robust anti-tumor…”
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Phase III, Randomized Study of the Effects of Parenteral Iron, Oral Iron, or No Iron Supplementation on the Erythropoietic Response to Darbepoetin Alfa for Patients With Chemotherapy-Associated Anemia
Published in Journal of clinical oncology (01-01-2011)“…Functional iron deficiency may impair response to erythropoiesis-stimulating agents (ESAs) in iron-replete patients with chemotherapy-associated anemia (CAA)…”
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Treatment of newly diagnosed multiple myeloma based on Mayo Stratification of Myeloma and Risk-adapted Therapy (mSMART): consensus statement
Published in Mayo Clinic proceedings (01-03-2007)“…Multiple myeloma is a neoplastic plasma cell dyscrasia that on a yearly basis affects nearly 17,000 individuals and kills more than 11,000. Although no cure…”
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Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone
Published in Blood (16-07-2009)“…The outcome of patients with multiple myeloma is dictated primarily by cytogenetic abnormalities and proliferative capacity of plasma cells. We studied the…”
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Mayo clinic consensus statement for the use of bisphosphonates in multiple myeloma
Published in Mayo Clinic proceedings (01-08-2006)“…Bisphosphonates are effective in the prevention and treatment of bone disease in multiple myeloma (MM). Osteonecrosis of the jaw is Increasingly recognized as…”
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Treatment of Newly Diagnosed Multiple Myeloma Based on Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART): Consensus Statement
Published in Mayo Clinic proceedings (2007)“…Multiple myeloma is a neoplastic plasma cell dyscrasia that on a yearly basis affects nearly 17,000 individuals and kills more than 11,000. Although no cure…”
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CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
Published in iScience (21-04-2023)“…Advances in the understanding of the tumor microenvironment have led to development of immunotherapeutic strategies, such as chimeric antigen receptor T cells…”
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Microclimate and limits to photosynthesis in a diverse community of hypolithic cyanobacteria in northern Australia
Published in Environmental microbiology (01-03-2010)“…Hypolithic microbes, primarily cyanobacteria, inhabit the highly specialized microhabitats under translucent rocks in extreme environments. Here we report…”
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Randomized Controlled Trial to Evaluate Transdermal Testosterone in Female Cancer Survivors With Decreased Libido; North Central Cancer Treatment Group Protocol N02C3
Published in JNCI : Journal of the National Cancer Institute (02-05-2007)“…Background Decreased libido is one of several changes in sexual function that are often experienced by female cancer patients. Transdermal testosterone therapy…”
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Salvage chemotherapy with rituximab DHAP for relapsed non-Hodgkin lymphoma: A phase II trial in the North Central Cancer Treatment Group
Published in Leukemia & lymphoma (01-06-2008)“…The aim of this study was to learn the toxicity and efficacy of adding 4 doses of rituximab to a standard platinum-based salvage regimen for relapsed CD20+…”
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Zoledronic acid for treatment of osteopenia and osteoporosis in women with primary breast cancer undergoing adjuvant aromatase inhibitor therapy
Published in Breast (Edinburgh) (01-04-2010)“…Abstract Background Postmenopausal women with osteoporosis/osteopenia are at increased risk of fracture. Aromatase inhibitors further increase bone loss in…”
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MD Anderson Manual of Medical Oncology
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Oferta obrigatória de planos de saúde individuais e familiares: livre iniciativa e direito fundamental à boa regulação
Published in Revista de Investigações Constitucionais (01-05-2018)“…O artigo analisa o dever de atuação da Agência Reguladora para corrigir a falha de mercado da coletivização do processo de compra dos planos de assistência…”
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Grass as an oesophageal foreign body in red-legged partridges
Published in Veterinary record (17-07-2010)“…Fig 2 Grass stem in the gizzard of a red-legged partridge The risk is removed only by topping the grass and removing the offending seed heads from the grass…”
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