Search Results - "Dalton, Heather"

Hematogenous Metastasis of Ovarian Cancer: Rethinking Mode of Spread by Pradeep, Sunila, Kim, Seung W., Wu, Sherry Y., Nishimura, Masato, Chaluvally-Raghavan, Pradeep, Miyake, Takahito, Pecot, Chad V., Kim, Sun-Jin, Choi, Hyun Jin, Bischoff, Farideh Z., Mayer, Julie Ann, Huang, Li, Nick, Alpa M., Hall, Carolyn S., Rodriguez-Aguayo, Cristian, Zand, Behrouz, Dalton, Heather J., Arumugam, Thiruvengadam, Lee, Ho Jeong, Han, Hee Dong, Cho, Min Soon, Rupaimoole, Rajesha, Mangala, Lingegowda S., Sehgal, Vasudha, Oh, Sang Cheul, Liu, Jinsong, Lee, Ju-Seog, Coleman, Robert L., Ram, Prahlad, Lopez-Berestein, Gabriel, Fidler, Isaiah J., Sood, Anil K.

“…Ovarian cancer has a clear predilection for metastasis to the omentum, but the underlying mechanisms involved in ovarian cancer spread are not well understood…”
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Constraints on the depths and temperatures of basaltic magma generation on Earth and other terrestrial planets using new thermobarometers for mafic magmas by Lee, Cin-Ty A., Luffi, Peter, Plank, Terry, Dalton, Heather, Leeman, William P.

“…Basaltic magmatism is a common feature of dynamically active terrestrial planets. The compositions of basalts reflect the temperatures and pressures of magma…”
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Role of Focal Adhesion Kinase in Regulating YB―1―Mediated Paclitaxel Resistance in Ovarian Cancer by YU KANG, WEI HU, RUPAIMOOLE, Rajesha, TAYLOR, Morgan, PRADEEP, Sunila, WU, Sherry Y, CHUNHUA LU, YUNFEI WEN, JIANFEI HUANG, JINSONG LIU, SOOD, Anil K, IVAN, Cristina, DALTON, Heather J, MIYAKE, Takahito, PECOT, Chad V, ZAND, Behrouz, TAO LIU, JIE HUANG, JENNINGS, Nicholas B

“…We previously found focal adhesion kinase (FAK) inhibition sensitizes ovarian cancer to taxanes; however, the mechanisms are not well understood. We…”
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Racial disparities in cervical cancer: Worse than we thought by Dalton, Heather J., Farley, John H.

“…Racial disparities in cervical cancer mortality continue to be a problem in the United States. Access to adequate cervical cancer screening and preventative…”
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Tumour angiogenesis regulation by the miR-200 family by Pecot, Chad V., Rupaimoole, Rajesha, Yang, Da, Akbani, Rehan, Ivan, Cristina, Lu, Chunhua, Wu, Sherry, Han, Hee-Dong, Shah, Maitri Y., Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Liu, Yuexin, Kim, Sang Bae, Unruh, Anna, Gonzalez-Villasana, Vianey, Huang, Li, Zand, Behrouz, Moreno-Smith, Myrthala, Mangala, Lingegowda S., Taylor, Morgan, Dalton, Heather J., Sehgal, Vasudha, Wen, Yunfei, Kang, Yu, Baggerly, Keith A., Lee, Ju-Seog, Ram, Prahlad T., Ravoori, Murali K., Kundra, Vikas, Zhang, Xinna, Ali-Fehmi, Rouba, Gonzalez-Angulo, Ana-Maria, Massion, Pierre P., Calin, George A., Lopez-Berestein, Gabriel, Zhang, Wei, Sood, Anil K.

“…The miR-200 family is well known to inhibit the epithelial–mesenchymal transition, suggesting it may therapeutically inhibit metastatic biology. However,…”
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Autocrine effects of tumor-derived complement by Cho, Min Soon, Vasquez, Hernan G, Rupaimoole, Rajesha, Pradeep, Sunila, Wu, Sherry, Zand, Behrouz, Han, Hee-Dong, Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Huang, Jie, Miyake, Takahito, Choi, Hyun-Jin, Dalton, Heather J, Ivan, Cristina, Baggerly, Keith, Lopez-Berestein, Gabriel, Sood, Anil K, Afshar-Kharghan, Vahid

“…We describe a role for the complement system in enhancing cancer growth. Cancer cells secrete complement proteins that stimulate tumor growth upon activation…”
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Activity of bevacizumab-containing regimens in recurrent low-grade serous ovarian or peritoneal cancer: A single institution experience by Dalton, Heather J, Fleming, Nicole D, Sun, Charlotte C, Bhosale, Priya, Schmeler, Kathleen M, Gershenson, David M

“…Abstract Objective The aim of this study was to evaluate the activity of bevacizumab in a cohort of women with recurrent low-grade serous carcinoma of the…”
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Erythropoietin Stimulates Tumor Growth via EphB4 by Pradeep, Sunila, Huang, Jie, Mora, Edna M., Nick, Alpa M., Cho, Min Soon, Wu, Sherry Y., Noh, Kyunghee, Pecot, Chad V., Rupaimoole, Rajesha, Stein, Martin A., Brock, Stephan, Wen, Yunfei, Xiong, Chiyi, Gharpure, Kshipra, Hansen, Jean M., Nagaraja, Archana S., Previs, Rebecca A., Vivas-Mejia, Pablo, Han, Hee Dong, Hu, Wei, Mangala, Lingegowda S., Zand, Behrouz, Stagg, Loren J., Ladbury, John E., Ozpolat, Bulent, Alpay, S. Neslihan, Nishimura, Masato, Stone, Rebecca L., Matsuo, Koji, Armaiz-Peña, Guillermo N., Dalton, Heather J., Danes, Christopher, Goodman, Blake, Rodriguez-Aguayo, Cristian, Kruger, Carola, Schneider, Armin, Haghpeykar, Shyon, Jaladurgam, Padmavathi, Hung, Mien-Chie, Coleman, Robert L., Liu, Jinsong, Li, Chun, Urbauer, Diana, Lopez-Berestein, Gabriel, Jackson, David B., Sood, Anil K.

“…While recombinant human erythropoietin (rhEpo) has been widely used to treat anemia in cancer patients, concerns about its adverse effects on patient survival…”
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Differential platelet levels affect response to taxane-based therapy in ovarian cancer by Bottsford-Miller, Justin, Choi, Hyun-Jin, Dalton, Heather J, Stone, Rebecca L, Cho, Min Soon, Haemmerle, Monika, Nick, Alpa M, Pradeep, Sunila, Zand, Behrouz, Previs, Rebecca A, Pecot, Chad V, Crane, Erin King, Hu, Wei, Lutgendorf, Susan K, Afshar-Kharghan, Vahid, Sood, Anil K

“…We hypothesized that platelet levels during therapy could serve as a biomarker for response to therapy and that manipulation of platelet levels could impact…”
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A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis by Masiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L., Buffa, Francesca M.

“…Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an…”
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FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal by Haemmerle, Monika, Bottsford-Miller, Justin, Pradeep, Sunila, Taylor, Morgan L, Choi, Hyun-Jin, Hansen, Jean M, Dalton, Heather J, Stone, Rebecca L, Cho, Min Soon, Nick, Alpa M, Nagaraja, Archana S, Gutschner, Tony, Gharpure, Kshipra M, Mangala, Lingegowda S, Rupaimoole, Rajesha, Han, Hee Dong, Zand, Behrouz, Armaiz-Pena, Guillermo N, Wu, Sherry Y, Pecot, Chad V, Burns, Alan R, Lopez-Berestein, Gabriel, Afshar-Kharghan, Vahid, Sood, Anil K

“…Recent studies in patients with ovarian cancer suggest that tumor growth may be accelerated following cessation of antiangiogenesis therapy; however, the…”
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Structured Curricular Change Fails to Combat Resident Burnout by Halista, Courtney E, Dalton, Heather A, Thornton, Jennifer A

“…During the 2020-2021 academic year, the Family Medicine (FM) faculty at David Grant USAF Medical Center (DGMC) incorporated Clinic First principles into the…”
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Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression by Rupaimoole, Rajesha, Wu, Sherry Y., Pradeep, Sunila, Ivan, Cristina, Pecot, Chad V., Gharpure, Kshipra M., Nagaraja, Archana S., Armaiz-Pena, Guillermo N., McGuire, Michael, Zand, Behrouz, Dalton, Heather J., Filant, Justyna, Miller, Justin Bottsford, Lu, Chunhua, Sadaoui, Nouara C., Mangala, Lingegowda S., Taylor, Morgan, van den Beucken, Twan, Koch, Elizabeth, Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Wouters, Bradly G., Radovich, Milan, Ivan, Mircea, Calin, George A., Zhang, Wei, Lopez-Berestein, Gabriel, Sood, Anil K.

“…Cancer-related deregulation of miRNA biogenesis has been suggested, but the underlying mechanisms remain elusive. Here we report a previously unrecognized…”
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Monocyte Subpopulations in Angiogenesis by DALTON, Heather J, ARMAIZ-PENA, Guillermo N, GONZALEZ-VILLASANA, Vianey, LOPEZ-BERESTEIN, Gabriel, BAR-ELI, Menashe, SOOD, Anil K

“…Growing understanding of the role of the tumor microenvironment in angiogenesis has brought monocyte-derived cells into focus. Monocyte subpopulations are an…”
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Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression by Dalton, Heather J, Pradeep, Sunila, McGuire, Michael, Hailemichael, Yared, Ma, Shaolin, Lyons, Yasmin, Armaiz-Pena, Guillermo N, Previs, Rebecca A, Hansen, Jean Marie, Rupaimoole, Rajesha, Gonzalez-Villasana, Vianey, Cho, Min Soon, Wu, Sherry Y, Mangala, Lingegowda S, Jennings, Nicholas B, Hu, Wei, Langley, Robert, Mu, Hong, Andreeff, Michael, Bar-Eli, Menashe, Overwijk, Willem, Ram, Prahlad, Lopez-Berestein, Gabriel, Coleman, Robert L, Sood, Anil K

“…VEGF-targeted therapies have modest efficacy in cancer patients, but acquired resistance is common. The mechanisms underlying such resistance are poorly…”
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Molecular Biomarkers of Residual Disease after Surgical Debulking of High-Grade Serous Ovarian Cancer by TUCKER, Susan L, GHARPURE, Kshipra, RUPAIMOOLE, Rajesha, LOPEZ-BERESTEIN, Gabriel, OZPOLAT, Bulent, IVAN, Cristina, WEI HU, BAGGERLY, Keith A, SOOD, Anil K, HERBRICH, Shelley M, UNRUH, Anna K, NICK, Alpa M, CRANE, Erin K, COLEMAN, Robert L, GUENTHOER, Jamie, DALTON, Heather J, WU, Sherry Y

“…Residual disease following primary cytoreduction is associated with adverse overall survival in patients with epithelial ovarian cancer. Accurate…”
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Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer by Gonzalez-Villasana, Vianey, Fuentes-Mattei, Enrique, Ivan, Cristina, Dalton, Heather J, Rodriguez-Aguayo, Cristian, Fernandez-de Thomas, Ricardo J, Aslan, Burcu, Del C Monroig, Paloma, Velazquez-Torres, Guermarie, Previs, Rebecca A, Pradeep, Sunila, Kahraman, Nermin, Wang, Huamin, Kanlikilicer, Pinar, Ozpolat, Bulent, Calin, George, Sood, Anil K, Lopez-Berestein, Gabriel

“…Zoledronic acid is being increasingly recognized for its antitumor properties, but the underlying functions are not well understood. In this study, we…”
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Therapeutic silencing of KRAS using systemically delivered siRNAs by Pecot, Chad V, Wu, Sherry Y, Bellister, Seth, Filant, Justyna, Rupaimoole, Rajesha, Hisamatsu, Takeshi, Bhattacharya, Rajat, Maharaj, Anshumaan, Azam, Salma, Rodriguez-Aguayo, Cristian, Nagaraja, Archana S, Morelli, Maria Pia, Gharpure, Kshipra M, Waugh, Trent A, Gonzalez-Villasana, Vianey, Zand, Behrouz, Dalton, Heather J, Kopetz, Scott, Lopez-Berestein, Gabriel, Ellis, Lee M, Sood, Anil K

“…Despite being among the most common oncogenes in human cancer, to date, there are no effective clinical options for inhibiting KRAS activity. We investigated…”
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2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity by Wu, Sherry Y., Yang, Xianbin, Gharpure, Kshipra M., Hatakeyama, Hiroto, Egli, Martin, McGuire, Michael H., Nagaraja, Archana S., Miyake, Takahito M., Rupaimoole, Rajesha, Pecot, Chad V., Taylor, Morgan, Pradeep, Sunila, Sierant, Malgorzata, Rodriguez-Aguayo, Cristian, Choi, Hyun J., Previs, Rebecca A., Armaiz-Pena, Guillermo N., Huang, Li, Martinez, Carlos, Hassell, Tom, Ivan, Cristina, Sehgal, Vasudha, Singhania, Richa, Han, Hee-Dong, Su, Chang, Kim, Ji Hoon, Dalton, Heather J., Kovvali, Chandra, Keyomarsi, Khandan, McMillan, Nigel A. J., Overwijk, Willem W., Liu, Jinsong, Lee, Ju-Seog, Baggerly, Keith A., Lopez-Berestein, Gabriel, Ram, Prahlad T., Nawrot, Barbara, Sood, Anil K.

“…Improving small interfering RNA (siRNA) efficacy in target cell populations remains a challenge to its clinical implementation. Here, we report a chemical…”
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Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer by Wen, Yunfei, Graybill, Whitney S, Previs, Rebecca A, Hu, Wei, Ivan, Cristina, Mangala, Lingegowda S, Zand, Behrouz, Nick, Alpa M, Jennings, Nicholas B, Dalton, Heather J, Sehgal, Vasudha, Ram, Prahlad, Lee, Ju-Seog, Vivas-Mejia, Pablo E, Coleman, Robert L, Sood, Anil K

“…Cancer cells are highly dependent on folate metabolism, making them susceptible to drugs that inhibit folate receptor activities. Targeting overexpressed…”
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