Search Results - "Dalton, E."
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Covalent Small Molecules as Enabling Platforms for Drug Discovery
Published in Chembiochem : a European journal of chemical biology (17-04-2020)“…Covalent drugs have experienced significant renewed interest in drug discovery. This resurgence has been accompanied by a better understanding of the…”
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A New Elixhauser-based Comorbidity Summary Measure to Predict In-Hospital Mortality
Published in Medical care (01-04-2015)“…BACKGROUND:Recently, van Walraven developed a weighted summary score (VW) based on the 30 comorbidities from the Elixhauser comorbidity system. One of the 30…”
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Neighborhood-level Social Vulnerability and Prevalence of Cardiovascular Risk Factors and Coronary Heart Disease
Published in Current problems in cardiology (01-08-2023)“…Social determinants of health are implicated in the geographic variation in cardiovascular diseases (CVDs). The social vulnerability index (SVI) is an estimate…”
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4
Creating synthetic populations in transplantation: A Bayesian approach enabling simulation without registry re-sampling
Published in PloS one (21-03-2024)“…Computer simulation has played a pivotal role in analyzing alternative organ allocation strategies in transplantation. The current approach to producing…”
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Solutions and case studies for thermally driven reactive transport and porosity evolution in geothermal systems (reactive Lauwerier problem)
Published in Hydrology and earth system sciences (23-10-2024)“…Subsurface non-isothermal fluid injection is a ubiquitous scenario in energy and water resource applications, which can lead to geochemical disequilibrium and…”
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Influence of Clay Wettability Alteration on Relative Permeability
Published in Geophysical research letters (28-09-2020)“…Understanding the wettability of porous materials is important to model fluid flow in the subsurface. One of the critical factors that influences wetting in…”
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Effect of Perioperative Intravenous Lidocaine Administration on Pain, Opioid Consumption, and Quality of Life after Complex Spine Surgery
Published in Anesthesiology (Philadelphia) (01-10-2013)“…The authors tested the primary hypothesis that perioperative IV lidocaine administration during spine surgery (and in the postanesthesia care unit for no more…”
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Synthesis of Heparan Sulfate- and Dermatan Sulfate-Related Oligosaccharides via Iterative Chemoselective Glycosylation Exploiting Conformationally Disarmed [2.2.2] l‑Iduronic Lactone Thioglycosides
Published in Journal of organic chemistry (06-12-2019)“…Heparan sulfate (HS) and dermatan sulfate (DS) are l-iduronic acid containing glycosaminoglycans (GAGs) which are implicated in a number of biological…”
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Variable light environments induce plastic spectral tuning by regional opsin coexpression in the African cichlid fish, Metriaclima zebra
Published in Molecular ecology (01-08-2015)“…Critical behaviours such as predation and mate choice often depend on vision. Visual systems are sensitive to the spectrum of light in their environment, which…”
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Dual Roles for Potassium Hydride in Haloarene Reduction: CSNAr and Single Electron Transfer Reduction via Organic Electron Donors Formed in Benzene
Published in Journal of the American Chemical Society (12-09-2018)“…Potassium hydride behaves uniquely and differently than sodium hydride toward aryl halides. Its reactions with a range of haloarenes, including designed…”
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Proximate and ultimate causes of variable visual sensitivities: Insights from cichlid fish radiations
Published in Genesis (New York, N.Y. : 2000) (01-06-2016)“…Summary Animals vary in their sensitivities to different wavelengths of light. Sensitivity differences can have fitness implications in terms of animals'…”
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12
Quantitative high-content imaging identifies novel regulators of Neo1 trafficking at endosomes
Published in Molecular biology of the cell (01-06-2017)“…P4-ATPases are a family of putative phospholipid flippases that regulate lipid membrane asymmetry, which is important for vesicle formation. Two yeast…”
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Stretch-shortening cycles protect against the age-related loss of power generation in rat single muscle fibres
Published in Experimental gerontology (01-06-2024)“…Aging is associated with impaired strength and power during isometric and shortening contractions, however, during lengthening (i.e., eccentric) contractions,…”
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Skin parasite landscape determines host infectiousness in visceral leishmaniasis
Published in Nature communications (05-07-2017)“…Increasing evidence suggests that the infectiousness of patients for the sand fly vector of visceral leishmaniasis is linked to parasites found in the skin…”
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Shear Induced Interactions Cause Polymer Compression
Published in Scientific reports (26-03-2020)“…Shear induced particle pressure occurs in concentrated suspensions of particles. Importantly, the significance of the shear induced particle pressure has not…”
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16
Flexible recalibration of binary clinical prediction models
Published in Statistics in medicine (30-01-2013)“…Calibration in binary prediction models, that is, the agreement between model predictions and observed outcomes, is an important aspect of assessing the…”
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Time course changes in in vivo muscle mechanical function and Ca2+ regulation of force following experimentally induced gradual ovarian failure in mice
Published in Experimental physiology (01-05-2024)“…The abrupt cessation of ovarian hormone release is associated with declines in muscle contractile function, yet the impact of gradual ovarian failure on muscle…”
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A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors
Published in PLoS computational biology (01-11-2024)“…Background The kallikrein-kinin system (KKS) is a complex biochemical pathway that plays a crucial role in regulating several physiological processes,…”
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A detailed investigation of the visual system and visual ecology of the Barrier Reef anemonefish, Amphiprion akindynos
Published in Scientific reports (11-11-2019)“…Vision plays a major role in the life of most teleosts, and is assumingly well adapted to each species ecology and behaviour. Using a multidisciplinary…”
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Effect of dexamethasone on the duration of interscalene nerve blocks with ropivacaine or bupivacaine
Published in British journal of anaesthesia : BJA (01-09-2011)“…Pain after shoulder surgery is often treated with interscalene nerve blocks. Single-injection blocks are effective, but time-limited. Adjuncts such as…”
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