Search Results - "Dalmolin, Rodrigo J S"
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Metagenomic Analyses Reveal the Influence of Depth Layers on Marine Biodiversity on Tropical and Subtropical Regions
Published in Microorganisms (Basel) (27-06-2023)“…The emergence of open ocean global-scale studies provided important information about the genomics of oceanic microbial communities. Metagenomic analyses shed…”
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ViaComplex: software for landscape analysis of gene expression networks in genomic context
Published in Bioinformatics (01-06-2009)“…ViaComplex is an open-source application that builds landscape maps of gene expression networks. The motivation for this software comes from two previous…”
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Sex-specific gene expression differences in the prefrontal cortex of major depressive disorder individuals
Published in Neuroscience (01-11-2024)“…•Identified 1169 transcriptionally altered genes (TAGs) linked to major depressive disorder.•Nearly 50% of TAGs exhibited transcript-level alterations,…”
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Correction: preferential duplication of intermodular hub genes: an evolutionary signature in eukaryotes genome networks
Published in PloS one (13-03-2015)Get full text
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Towards a genome-wide transcriptogram: the Saccharomyces cerevisiae case
Published in Nucleic acids research (01-04-2011)“…Analysis of genome-wide expression data poses a challenge to extract relevant information. The usual approaches compare cellular expression levels relative to…”
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Prediction of long noncoding RNA functions with co-expression network in esophageal squamous cell carcinoma
Published in BMC cancer (24-03-2015)“…Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome. They have important regulatory functions in chromatin remodeling and gene expression…”
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MEDUSA: A Pipeline for Sensitive Taxonomic Classification and Flexible Functional Annotation of Metagenomic Shotgun Sequences
Published in Frontiers in genetics (07-03-2022)“…Metagenomic studies unravel details about the taxonomic composition and the functions performed by microbial communities. As a complete metagenomic analysis…”
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Evolutionary origins of human apoptosis and genome-stability gene networks
Published in Nucleic acids research (01-11-2008)“…Apoptosis is essential for complex multicellular organisms and its failure is associated with genome instability and cancer. Interactions between apoptosis and…”
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Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach
Published in npj aging (24-08-2023)“…Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to immunosenescence and certain age-dependent medical conditions…”
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Systems Biology-Based Analysis Indicates Global Transcriptional Impairment in Lead-Treated Human Neural Progenitor Cells
Published in Frontiers in genetics (10-09-2019)“…Lead poisoning effects are wide and include nervous system impairment, peculiarly during development, leading to neural damage. Lead interaction with calcium…”
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Preferential duplication of intermodular hub genes: an evolutionary signature in eukaryotes genome networks
Published in PloS one (26-02-2013)“…Whole genome protein-protein association networks are not random and their topological properties stem from genome evolution mechanisms. In fact, more…”
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Evolutionary plasticity determination by orthologous groups distribution
Published in Biology direct (17-05-2011)“…Genetic plasticity may be understood as the ability of a functional gene network to tolerate alterations in its components or structure. Usually, the studies…”
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Bridge: A New Algorithm for Rooting Orthologous Genes in Large-Scale Evolutionary Analyses
Published in Molecular biology and evolution (01-02-2024)“…Orthology information has been used for searching patterns in high-dimensional data, allowing transferring functional information between species. The key…”
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TreeAndLeaf: an R/Bioconductor package for graphs and trees with focus on the leaves
Published in Bioinformatics (Oxford, England) (07-02-2022)“…Abstract Motivation Dendrogram is a classical diagram for visualizing binary trees. Although efficient to represent hierarchical relations, it provides limited…”
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Transcriptogramer: an R/Bioconductor package for transcriptional analysis based on protein-protein interaction
Published in Bioinformatics (Oxford, England) (15-08-2019)“…Several freely available tools perform analysis using algorithms developed to identify significant variation of gene expression individually. The…”
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Which came first, the transcriptional regulator or its target genes? An evolutionary perspective into the construction of eukaryotic regulons
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-06-2020)“…Eukaryotic regulons are regulatory units formed by a set of genes under the control of the same transcription factor (TF). Despite the functional plasticity,…”
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NFκB inhibitors induce cell death in glioblastomas
Published in Biochemical pharmacology (01-02-2011)“…Identification of novel target pathways in glioblastoma (GBM) remains critical due to poor prognosis, inefficient therapies and recurrence associated with…”
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Ancestry analysis indicates two different sets of essential genes in eukaryotic model species
Published in Functional & integrative genomics (01-07-2021)“…Essential genes are so-called because they are crucial for organism perpetuation. Those genes are usually related to essential functions to cellular metabolism…”
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A systematic review of human antioxidant genes
Published in Frontiers in bioscience (01-01-2009)“…The balance between production and clearance of reactive species is essential for cell survival. Antioxidant cellular systems evolved to maintain a redox…”
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Retinol and retinoic acid increase MMP-2 activity by different pathways in cultured Sertoli cells
Published in Free radical research (01-12-2007)“…Diseases such as atherosclerosis, arthritis and cancer have been related with imbalance in ROS production and failures in regulation of the MMPs. Authors…”
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