Search Results - "Dallman, Timothy J"
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1
Performance comparison of benchtop high-throughput sequencing platforms
Published in Nature biotechnology (01-05-2012)“…Small sequencing machines no bigger than a laser printer have many potential applications in diagnostics and public health. Loman et al . compare the quality,…”
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2
Comparative analysis of core genome MLST and SNP typing within a European Salmonella serovar Enteritidis outbreak
Published in International journal of food microbiology (02-06-2018)“…Multi-country outbreaks of foodborne bacterial disease present challenges in their detection, tracking, and notification. As food is increasingly distributed…”
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3
Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species
Published in Nature communications (13-04-2018)“…Horizontal gene transfer has played a role in developing the global public health crisis of antimicrobial resistance (AMR). However, the dynamics of AMR…”
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4
Rapid draft sequencing and real-time nanopore sequencing in a hospital outbreak of Salmonella
Published in Genome Biology (30-05-2015)“…Foodborne outbreaks of Salmonella remain a pressing public health concern. We recently detected a large outbreak of Salmonella enterica serovar Enteritidis…”
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Prediction of Phenotypic Antimicrobial Resistance Profiles From Whole Genome Sequences of Non-typhoidal Salmonella enterica
Published in Frontiers in microbiology (27-03-2018)“…Surveillance of antimicrobial resistance (AMR) in non-typhoidal (NTS), is essential for monitoring transmission of resistance from the food chain to humans,…”
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Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation
Published in PLoS genetics (08-06-2020)“…Salmonella enterica serotype Typhimurium (S. Typhimurium) is a leading cause of gastroenteritis and bacteraemia worldwide, and a model organism for the study…”
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Utility of Whole-Genome Sequencing of Escherichia coli O157 for Outbreak Detection and Epidemiological Surveillance
Published in Journal of clinical microbiology (01-11-2015)“…Detailed laboratory characterization of Escherichia coli O157 is essential to inform epidemiological investigations. This study assessed the utility of…”
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8
Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei
Published in Nature communications (11-05-2021)“…Shigella sonnei is the most common agent of shigellosis in high-income countries, and causes a significant disease burden in low- and middle-income countries…”
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Development and validation of a random forest algorithm for source attribution of animal and human Salmonella Typhimurium and monophasic variants of S. Typhimurium isolates in England and Wales utilising whole genome sequencing data
Published in Frontiers in microbiology (12-03-2024)“…Source attribution has traditionally involved combining epidemiological data with different pathogen characterisation methods, including 7-gene multi locus…”
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10
Inspection of chicken wings and legs for animal welfare monitoring using X-ray computed tomography, visual examination, and histopathology
Published in Poultry science (01-03-2024)“…In broiler chickens, fractures of wings and legs are recorded at poultry slaughterhouses based on the time of occurrence. Prekilling (PRE) fractures occur…”
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Genomic epidemiology of Shigella in the United Kingdom shows transmission of pathogen sublineages and determinants of antimicrobial resistance
Published in Scientific reports (09-05-2018)“…Shigella are globally important diarrhoeal pathogens that are endemic in low-to-middle income nations and also occur in high income nations, typically in…”
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Informal genomic surveillance of regional distribution of Salmonella Typhi genotypes and antimicrobial resistance via returning travellers
Published in PLoS neglected tropical diseases (01-09-2019)“…Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typhoid fever, a systemic human infection with a burden exceeding 20 million cases each…”
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Highly Pathogenic Clone of Shiga Toxin-Producing Escherichia coli O157:H7, England and Wales
Published in Emerging infectious diseases (01-12-2018)“…We used whole-genome sequencing to investigate the evolutionary context of an emerging highly pathogenic strain of Shiga toxin-producing Escherichia coli…”
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14
SGI-4 in Monophasic Salmonella Typhimurium ST34 Is a Novel ICE That Enhances Resistance to Copper
Published in Frontiers in microbiology (2019)“…A multi drug resistant 4,[5],12:i- of sequence type 34 (monophasic . Typhimurium ST34) is a current pandemic clone associated with livestock, particularly…”
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Comparison of single-nucleotide variants identified by Illumina and Oxford Nanopore technologies in the context of a potential outbreak of Shiga toxin-producing Escherichia coli
Published in Gigascience (01-08-2019)“…We aimed to compare Illumina and Oxford Nanopore Technology sequencing data from the 2 isolates of Shiga toxin-producing Escherichia coli (STEC) O157:H7 to…”
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A One Health Perspective on Salmonella enterica Serovar Infantis, an Emerging Human Multidrug-Resistant Pathogen
Published in Emerging infectious diseases (01-04-2024)“…Salmonella enterica serovar Infantis presents an ever-increasing threat to public health because of its spread throughout many countries and association with…”
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Re-analysis of an outbreak of Shiga toxin-producing Escherichia coli O157:H7 associated with raw drinking milk using Nanopore sequencing
Published in Scientific reports (09-03-2024)“…The aim of this study was to compare Illumina and Oxford Nanopore Technology (ONT) sequencing data to quantify genetic variation to assess within-outbreak…”
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Identification of Salmonella for public health surveillance using whole genome sequencing
Published in PeerJ (San Francisco, CA) (05-04-2016)“…In April 2015, Public Health England implemented whole genome sequencing (WGS) as a routine typing tool for public health surveillance of Salmonella, adopting…”
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Genomic surveillance detects Salmonella enterica serovar Paratyphi A harbouring blaCTX-M-15 from a traveller returning from Bangladesh
Published in PloS one (01-01-2020)“…Whole genome sequencing (WGS) has been used routinely by Public Health England (PHE) for identification, surveillance and monitoring of resistance determinants…”
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Rapid geographical source attribution of Salmonella enterica serovar Enteritidis genomes using hierarchical machine learning
Published in eLife (12-04-2023)“…serovar Enteritidis is one of the most frequent causes of Salmonellosis globally and is commonly transmitted from animals to humans by the consumption of…”
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