Search Results - "Dallman, Julia E."

Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease by Buglo, Elena, Sarmiento, Evan, Martuscelli, Nicole Belliard, Sant, David W, Danzi, Matt C, Abrams, Alexander J, Dallman, Julia E, Züchner, Stephan

“…A phenomenon of genetic compensation is commonly observed when an organism with a disease-bearing mutation shows incomplete penetrance of the disease…”
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Cryptic Amyloidogenic Elements in the 3′ UTRs of Neurofilament Genes Trigger Axonal Neuropathy by Rebelo, Adriana P., Abrams, Alexander J., Cottenie, Ellen, Horga, Alejandro, Gonzalez, Michael, Bis, Dana M., Sanchez-Mejias, Avencia, Pinto, Milena, Buglo, Elena, Markel, Kasey, Prince, Jeffrey, Laura, Matilde, Houlden, Henry, Blake, Julian, Woodward, Cathy, Sweeney, Mary G., Holton, Janice L., Hanna, Michael, Dallman, Julia E., Auer-Grumbach, Michaela, Reilly, Mary M., Zuchner, Stephan

“…Abnormal protein aggregation is observed in an expanding number of neurodegenerative diseases. Here, we describe a mechanism for intracellular toxic protein…”
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Drugs prescribed for Phelan-McDermid syndrome differentially impact sensory behaviors in shank3 zebrafish models. [version 1; peer review: 2 approved with reservations] by Kozol, Robert A., Dallman, Julia E.

“…Background: Altered sensory processing is a pervasive symptom in individuals with Autism Spectrum Disorders (ASD); people with Phelan McDermid syndrome (PMS),…”
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Intestinal dysmotility in a zebrafish ( Danio rerio ) shank3a;shank3b mutant model of autism by James, David M, Kozol, Robert A, Kajiwara, Yuji, Wahl, Adam L, Storrs, Emily C, Buxbaum, Joseph D, Klein, Mason, Moshiree, Baharak, Dallman, Julia E

“…Autism spectrum disorder (ASD) is currently estimated to affect more than 1% of the world population. For people with ASD, gastrointestinal (GI) distress is a…”
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Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish by Kozol, Robert A, Abrams, Alexander J, James, David M, Buglo, Elena, Yan, Qing, Dallman, Julia E

“…Zebrafish are a unique cell to behavior model for studying the basic biology of human inherited neurological conditions. Conserved vertebrate genetics and…”
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Context-dependent hyperactivity in syngap1a and syngap1b zebrafish models of SYNGAP1-related disorder by Sumathipala, Sureni H, Khan, Suha, Kozol, Robert A, Araki, Yoichi, Syed, Sheyum, Huganir, Richard L, Dallman, Julia E

“…SYNGAP1-related disorder (SYNGAP1-RD) is a prevalent genetic form of Autism Spectrum Disorder and Intellectual Disability (ASD/ID) and is caused by or…”
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A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure by Hung, Christina Y, Volkmar, Barbara, Baker, James D, Bauer, Johann W, Gussoni, Emanuela, Hainzl, Stefan, Klausegger, Alfred, Lorenzo, Jose, Mihalek, Ivana, Rittinger, Olaf, Tekin, Mustafa, Dallman, Julia E, Bodamer, Olaf A

“…Primordial growth failure has been linked to defects in the biology of cell division and replication. The complex processes involved in microtubule spindle…”
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Elevated preoptic brain activity in zebrafish glial glycine transporter mutants is linked to lethargy-like behaviors and delayed emergence from anesthesia by Venincasa, Michael J., Randlett, Owen, Sumathipala, Sureni H., Bindernagel, Richard, Stark, Matthew J., Yan, Qing, Sloan, Steven A., Buglo, Elena, Meng, Qing Cheng, Engert, Florian, Züchner, Stephan, Kelz, Max B., Syed, Sheyum, Dallman, Julia E.

“…Delayed emergence from anesthesia was previously reported in a case study of a child with Glycine Encephalopathy. To investigate the neural basis of this…”
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The Gut-Brain-Microbiome Axis and Its Link to Autism: Emerging Insights and the Potential of Zebrafish Models by James, David M, Davidson, Elizabeth A, Yanes, Julio, Moshiree, Baharak, Dallman, Julia E

“…Research involving autism spectrum disorder (ASD) most frequently focuses on its key diagnostic criteria: restricted interests and repetitive behaviors,…”
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Restoring Shank3 in the rostral brainstem of shank3ab−/− zebrafish autism models rescues sensory deficits by Kozol, Robert A., James, David M., Varela, Ivan, Sumathipala, Sureni H., Züchner, Stephan, Dallman, Julia E.

“…People with Phelan-McDermid Syndrome, caused by mutations in the SHANK3 gene, commonly exhibit reduced responses to sensory stimuli; yet the changes in…”
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Distinct phenotypes in zebrafish models of human startle disease by Ganser, Lisa R, Yan, Qing, James, Victoria M, Kozol, Robert, Topf, Maya, Harvey, Robert J, Dallman, Julia E

“…Abstract Startle disease is an inherited neurological disorder that causes affected individuals to suffer noise- or touch-induced non-epileptic seizures,…”
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Synaptic Homeostasis in a Zebrafish Glial Glycine Transporter Mutant by Mongeon, Rebecca, Gleason, Michelle R, Masino, Mark A, Fetcho, Joseph R, Mandel, Gail, Brehm, Paul, Dallman, Julia E

“…1 Howard Hughes Medical Institute and 2 Department of Neurobiology and Behavior, State University of New York, Stony Brook; and 3 Department of Neurobiology…”
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Gastrointestinal Dysfunction in Genetically Defined Neurodevelopmental Disorders by Davidson, Elizabeth A, Holingue, Calliope, Jimenez-Gomez, Andres, Dallman, Julia E, Moshiree, Baharak

“…Gastrointestinal symptoms are common in most forms of neurodevelopment disorders (NDDs) such as in autism spectrum disorders (ASD). The current…”
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A Conserved Role But Different Partners for the Transcriptional Corepressor CoREST in Fly and Mammalian Nervous System Formation by Dallman, Julia E, Allopenna, Janet, Bassett, Andrew, Travers, Andrew, Mandel, Gail

“…Identification of conserved proteins that act to establish the neuronal phenotype has relied predominantly on structural homologies of the underlying genes. In…”
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Drugs prescribed for Phelan-McDermid syndrome differentially impact sensory behaviors in shank3 zebrafish models. [version 2; peer review: 2 approved] by Kozol, Robert A., Dallman, Julia E.

“…Background: Altered sensory processing is a pervasive symptom in individuals with Autism Spectrum Disorders (ASD); people with Phelan McDermid syndrome (PMS),…”
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Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development by Yan, Qing, Zhai, Lu, Zhang, Bo, Dallman, Julia E.

“…To generate rhythmic motor behaviors, both single neurons and neural circuits require a balance between excitatory inputs that trigger action potentials and…”
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Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis by Kozol, Robert A, Cukier, Holly N, Zou, Bing, Mayo, Vera, De Rubeis, Silvia, Cai, Guiqing, Griswold, Anthony J, Whitehead, Patrice L, Haines, Jonathan L, Gilbert, John R, Cuccaro, Michael L, Martin, Eden R, Baker, James D, Buxbaum, Joseph D, Pericak-Vance, Margaret A, Dallman, Julia E

“…Despite significant progress in the genetics of autism spectrum disorder (ASD), how genetic mutations translate to the behavioral changes characteristic of ASD…”
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Zebrafish: A Pharmacogenetic Model for Anesthesia by Bedell, Victoria, Buglo, Elena, Marcato, Daniel, Pylatiuk, Christian, Mikut, Ralf, Stegmaier, Johannes, Scudder, Will, Wray, Maxwell, Züchner, Stephan, Strähle, Uwe, Peravali, Ravindra, Dallman, Julia E

“…General anesthetics are small molecules that interact with and effect the function of many different proteins to promote loss of consciousness, amnesia, and…”
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Spontaneous activity regulates calcium-dependent K+ current expression in developing ascidian muscle by Dallman, Julia E., Davis, Anna K., Moody, William J.

“…In embryonic ascidian muscle, outward K + currents develop in two stages: the initial expression of a slowly activating, voltage-gated K + current ( I Kv )…”
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Knock-down DHDDS expression induces photoreceptor degeneration in zebrafish by Wen, Rong, Dallman, Julia E, Li, Yiwen, Züchner, Stephan L, Vance, Jeffery M, Peričak-Vance, Margaret A, Lam, Byron L

“…A mutation in the dehydrodolichol diphosphate synthase (DHDDS) was recently identified as the cause of a subtype of recessive retinitis pigmentosa (RP)…”
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