Search Results - "Dalla Via, L."
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1
Synthesis and biological activity of 1,4-dihydrobenzothiopyrano[4,3- c]pyrazole derivatives, novel pro-apoptotic mitochondrial targeted agents
Published in Bioorganic & medicinal chemistry (2009)“…A series of new 1,4-dihydrobenzothiopyrano[4,3- c]pyrazole derivatives were synthesized. Compound 3c shows the higher antiproliferative effect on tumor cell…”
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2
Synthesis and antiproliferative activity of some new DNA-targeted alkylating pyrroloquinolines
Published in Bioorganic & medicinal chemistry (15-02-2004)“…Two novel DNA-direct alkylating agents, consisting of aniline mustard linked to an angular 3H-pyrrolo[3,2- f]quinoline nucleus, were synthetized and assayed…”
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3
Respiratory Disorders and Hospitalization Rates During the Second RSV Season in Preterm Infants Who Received Palivizumab Prophylaxis During Their First RSV Season
Published in Journal of chemotherapy (Florence) (01-06-2009)“…This prospective study evaluated the frequency and severity of respiratory symptoms during the second respiratory syncytial virus (RSV) season in an Italian…”
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4
Anti-inflammatory and antiproliferative evaluation of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene from Verbesina persicifolia and derivatives
Published in Bioorganic & medicinal chemistry (01-09-2015)“…[Display omitted] The anti-inflammatory and antiproliferative activities of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene (1) and of three derivatives, namely…”
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5
Discovery of a new anilino-3H-pyrrolo[3,2-f]quinoline derivative as potential anti-cancer agent
Published in European journal of medicinal chemistry (01-02-2008)“…The newly synthesized 1-[4-(3H-pyrrolo[3,2-f]quinolin-9-ylamino)-phenyl]-ethanone hydrochloride showed high antiproliferative activity by mixed mechanisms of…”
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6
Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter
Published in The Journal of biological chemistry (15-09-1992)“…We present evidence that polyamine uptake into rat liver mitochondria is mediated by a specific polyamine uniporter. Polyamine transport is not mediated by the…”
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7
Synthesis and antiproliferative evaluation of new aryl substituted pyrido[3′,2′:5,6]thiopyrano[4,3-c]pyrazoles
Published in Journal of heterocyclic chemistry (01-11-2005)“…The preparation and the cytotoxic properties of new derivatives of the planar pyrido[3′,2′:5,6]thiopyrano‐[4,3‐c]pyrazole system, carrying an arylic side group…”
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8
Correlation between cytosolic Ca2+ concentration, protein phosphorylation and platelet secretion
Published in Cell calcium (Edinburgh) (01-11-1996)“…Addition of the calcium-ionophore ionomycin to acetylsalicylate-treated platelets suspended in a low Ca2+ concentration-containing medium (about 0.1 microM),…”
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9
Synthesis and in Vitro and in Vivo Antitumor Activity of 2-Phenylpyrroloquinolin-4-ones
Published in Journal of medicinal chemistry (05-05-2005)“…In our search for potential new anticancer drugs, we designed and synthesized a series of tricyclic compounds containing the antimitotic 2-phenylazaflavone…”
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10
Electrophoretic polyamine transport in rat liver mitochondria
Published in Amino acids (01-02-1992)“…Naturally occurring polyamines (spermidine, putrescine, cadaverine), as the well studied spermine, are transported into rat liver mitochondrial matrix provided…”
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11
Photochemotherapy in the treatment of cancer
Published in Current medicinal chemistry (01-10-2001)“…The development of therapies which are selective for tumor tissues is one of the most important goals in anticancer research. Within this framework…”
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12
Discovery of a new anilino-3 H-pyrrolo[3,2- f]quinoline derivative as potential anti-cancer agent
Published in European journal of medicinal chemistry (2008)“…The newly synthesized 1-[4-(3 H-pyrrolo[3,2- f]quinolin-9-ylamino)-phenyl]-ethanone hydrochloride showed high antiproliferative activity by mixed mechanisms of…”
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13
Review of binding methods and detection of Al(III) binding events in trypsin and DL-DPPC liposomes by a general thermodynamic model
Published in Coordination chemistry reviews (03-06-2002)“…In this paper are reviewed some of the most useful binding formalisms which have been developed in order to investigate the diversity of the commonly…”
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14
New water soluble pyrroloquinoline derivatives as new potential anticancer agents
Published in Bioorganic & medicinal chemistry (01-08-2005)“…A new class of water soluble 3 H-pyrrolo[3,2- f]quinoline derivatives has been synthesized and investigated as potential anticancer drugs. Water solubility…”
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15
Novel Pyrone Side Tetracyclic Psoralen Derivatives: Synthesis and Photobiological Evaluation
Published in Journal of medicinal chemistry (28-08-2003)“…This study reports the synthesis of tetrahydrobenzo- (4 − 6) and benzopsoralen (7 − 9) derivatives obtained by condensing the fourth ring to the pyrone side of…”
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16
New Tetracyclic Analogues of Photochemotherapeutic Drugs 5-MOP and 8-MOP: Synthesis, DNA Interaction, and Antiproliferative Activity
Published in Journal of medicinal chemistry (21-10-1999)“…The synthesis of new tetrahydrobenzo- and benzopsoralen derivatives carrying at position 5 or 8 of the furocoumarin moiety a methoxy, hydroxy, or…”
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17
A new benzoangelicin with strong photobiological activity
Published in Bioorganic & medicinal chemistry letters (17-01-2000)“…Benzoangelicins 4-6 were synthesized in good yields from 7-hydroxy-5-methoxy-4-methylcoumarin (1). In the absence of UVA radiation, compounds 5 and 6 were only…”
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18
Binding studies on aluminum(III)–albumin interaction
Published in Archives of biochemistry and biophysics (01-09-2003)“…The present paper reports a quantitative investigation on the binding of aluminum to human serum albumin. Equilibrium dialysis and a general thermodynamic…”
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19
Dialkylaminoalkylindolonaphthyridines as potential antitumour agents: synthesis, cytotoxicity and DNA binding properties
Published in European journal of medicinal chemistry (01-06-2002)“…The synthesis of new planar derivatives characterised by the presence of an indolonaphthyridine nucleus, carrying a dimethylaminoethyl or a dimethylaminopropyl…”
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20
Transport and action of spermine in rat heart mitochondria
Published in Cardioscience (01-12-1990)“…At concentrations of 0.5-1.0 mM, spermine fully prevents the fall of membrane potential induced in rat heart mitochondria either by aging at room temperature…”
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