Search Results - "Dalgaard, Marlene"

Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring by David, Arthur, Chaker, Jade, Léger, Thibaut, Al-Salhi, Raghad, Dalgaard, Marlene D., Styrishave, Bjarne, Bury, Daniel, Koch, Holger M., Jégou, Bernard, Kristensen, David M.

“…•Non-targeted HRMS method identified overlooked acetaminophen metabolites in human.•Thiomethyl metabolites showed delayed appearance with peak time at 24 h in…”
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Ocular surface microbiota in patients with aqueous tear-deficient dry eye by Andersson, Jasmine, Vogt, Josef K., Dalgaard, Marlene D., Pedersen, Oluf, Holmgaard, Kim, Heegaard, Steffen

“…An altered ocular surface microbiota may contribute to the pathophysiology of dry eye disease. The aim of the study was to explore potential differences in…”
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Genomic GC-Content Affects the Accuracy of 16S rRNA Gene Sequencing Based Microbial Profiling due to PCR Bias by Laursen, Martin F, Dalgaard, Marlene D, Bahl, Martin I

“…Profiling of microbial community composition is frequently performed by partial 16S rRNA gene sequencing on benchtop platforms following PCR amplification of…”
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Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity by Belling, Kirstine, Russo, Francesco, Jensen, Anders B, Dalgaard, Marlene D, Westergaard, David, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Juul, Anders, Brunak, Søren

“…Klinefelter syndrome (KS) (47,XXY) is the most common male sex chromosome aneuploidy. Diagnosis and clinical supervision remain a challenge due to varying…”
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Corrigendum: Genomic GC-Content Affects the Accuracy of 16S rRNA Gene Sequencing Based Microbial Profiling due to PCR Bias by Laursen, Martin F, Dalgaard, Marlene D, Bahl, Martin I

“…[This corrects the article DOI: 10.3389/fmicb.2017.01934.]…”
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Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut by Roager, Henrik M., Hansen, Lea B. S., Bahl, Martin I., Frandsen, Henrik L., Carvalho, Vera, Gøbel, Rikke J., Dalgaard, Marlene D., Plichta, Damian R., Sparholt, Morten H., Vestergaard, Henrik, Hansen, Torben, Sicheritz-Pontén, Thomas, Nielsen, H. Bjørn, Pedersen, Oluf, Lauritzen, Lotte, Kristensen, Mette, Gupta, Ramneek, Licht, Tine R.

“…Little is known about how colonic transit time relates to human colonic metabolism and its importance for host health, although a firm stool consistency, a…”
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High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology by Nag, Sidsel, Dalgaard, Marlene D., Kofoed, Poul-Erik, Ursing, Johan, Crespo, Marina, Andersen, Lee O’Brien, Aarestrup, Frank Møller, Lund, Ole, Alifrangis, Michael

“…Genetic polymorphisms in P. falciparum can be used to indicate the parasite’s susceptibility to antimalarial drugs as well as its geographical origin. Both of…”
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Using electronic patient records to discover disease correlations and stratify patient cohorts by Roque, Francisco S, Jensen, Peter B, Schmock, Henriette, Dalgaard, Marlene, Andreatta, Massimo, Hansen, Thomas, Søeby, Karen, Bredkjær, Søren, Juul, Anders, Werge, Thomas, Jensen, Lars J, Brunak, Søren

“…Electronic patient records remain a rather unexplored, but potentially rich data source for discovering correlations between diseases. We describe a general…”
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Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation by Winge, Sofia B, Dalgaard, Marlene D, Jensen, Jacob M, Graem, Niels, Schierup, Mikkel H, Juul, Anders, Rajpert-De Meyts, Ewa, Almstrup, Kristian

“…Abstract In humans, the most common sex chromosomal disorder is Klinefelter syndrome (KS), caused by the presence of one or more extra X-chromosomes. KS…”
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Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor by Wang, Zhaoming, McGlynn, Katherine A, Rajpert-De Meyts, Ewa, Bishop, D Timothy, Chung, Charles C, Dalgaard, Marlene D, Greene, Mark H, Gupta, Ramneek, Grotmol, Tom, Haugen, Trine B, Karlsson, Robert, Litchfield, Kevin, Mitra, Nandita, Nielsen, Kasper, Pyle, Louise C, Schwartz, Stephen M, Thorsson, Vésteinn, Vardhanabhuti, Saran, Wiklund, Fredrik, Turnbull, Clare, Chanock, Stephen J, Kanetsky, Peter A, Nathanson, Katherine L

“…Katherine Nathanson, Peter Kanetsky and colleagues present a meta-analysis of five genome-wide association studies of testicular germ cell tumor (TGCT). They…”
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Predicting Hearing Loss in Testicular Cancer Patients after Cisplatin-Based Chemotherapy by Garcia, Sara L, Lauritsen, Jakob, Christiansen, Bernadette K, Hansen, Ida F, Bandak, Mikkel, Dalgaard, Marlene D, Daugaard, Gedske, Gupta, Ramneek

“…Testicular cancer is predominantly curable, but the long-term side effects of chemotherapy have a severe impact on life quality. In this research study, we…”
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Contamination of the Arctic reflected in microbial metagenomes from the Greenland ice sheet by Hauptmann, Aviaja L, Sicheritz-Pontén, Thomas, Cameron, Karen A, Bælum, Jacob, Plichta, Damian R, Dalgaard, Marlene, Stibal, Marek

“…Globally emitted contaminants accumulate in the Arctic and are stored in the frozen environments of the cryosphere. Climate change influences the release of…”
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Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease by Izarzugaza, Jose M G, Ellesøe, Sabrina G, Doganli, Canan, Ehlers, Natasja Spring, Dalgaard, Marlene D, Audain, Enrique, Dombrowsky, Gregor, Banasik, Karina, Sifrim, Alejandro, Wilsdon, Anna, Thienpont, Bernard, Breckpot, Jeroen, Gewillig, Marc, Brook, J David, Hitz, Marc-Phillip, Larsen, Lars A, Brunak, Søren

“…Congenital heart disease (CHD) occurs in almost 1% of newborn children and is considered a multifactorial disorder. CHD may segregate in families due to…”
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Genetically Inferred Telomere Length and Testicular Germ Cell Tumor Risk by Brown, Derek W, Lan, Qing, Rothman, Nathaniel, Pluta, John, Almstrup, Kristian, Dalgaard, Marlene D, Greene, Mark H, Grotmol, Tom, Loveday, Chey, Schwartz, Stephen M, Turnbull, Clare, Wiklund, Fredrik, Kanetsky, Peter A, Nathanson, Katherine L, McGlynn, Katherine A, Machiela, Mitchell J

“…Studies evaluating the association between peripheral blood leukocyte telomere length (LTL) and testicular germ cell tumor (TGCT) risk have produced…”
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Ocular Surface Microbiota in Contact Lens Users and Contact-Lens-Associated Bacterial Keratitis by Andersson, Jasmine, Vogt, Josef K., Dalgaard, Marlene D., Pedersen, Oluf, Holmgaard, Kim, Heegaard, Steffen

“…Our objectives were to investigate whether the conjunctival microbiota is altered by contact lens wear and/or bacterial keratitis and to explore the hypothesis…”
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Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents by Lottrup, Grete, Belling, Kirstine, Leffers, Henrik, Nielsen, John E, Dalgaard, Marlene D, Juul, Anders, Skakkebæk, Niels E, Brunak, Søren, Rajpert-De Meyts, Ewa

“…Do human adult Leydig cells (ALCs) within hyperplastic micronodules display characteristics of foetal LCs (FLCs)? The gene expression profiles of FLCs and all…”
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Prediction of Nephrotoxicity Associated With Cisplatin-Based Chemotherapy in Testicular Cancer Patients by Garcia, Sara L, Lauritsen, Jakob, Zhang, Zeyu, Bandak, Mikkel, Dalgaard, Marlene D, Nielsen, Rikke L, Daugaard, Gedske, Gupta, Ramneek

“…Cisplatin-based chemotherapy may induce nephrotoxicity. This study presents a random forest predictive model that identifies testicular cancer patients at risk…”
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A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation by Dalgaard, Marlene D, Weinhold, Nils, Edsgärd, Daniel, Silver, Jeremy D, Pers, Tune H, Nielsen, John E, Jørgensen, Niels, Juul, Anders, Gerds, Thomas A, Giwercman, Aleksander, Giwercman, Yvonne L, Cohn-Cedermark, Gabriella, Virtanen, Helena E, Toppari, Jorma, Daugaard, Gedske, Jensen, Thomas S, Brunak, Søren, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Leffers, Henrik, Gupta, Ramneek

“…Testicular dysgenesis syndrome (TDS) is a common disease that links testicular germ cell cancer, cryptorchidism and some cases of hypospadias and male…”
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NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia by Tulstrup, Morten, Grosjean, Marie, Nielsen, Stine Nygaard, Grell, Kathrine, Wolthers, Benjamin Ole, Wegener, Peder Skov, Jonsson, Olafur Gisli, Lund, Bendik, Harila-Saari, Arja, Abrahamsson, Jonas, Vaitkeviciene, Goda, Pruunsild, Kaie, Toft, Nina, Holm, Mette, Hulegårdh, Erik, Liestøl, Sigurd, Griskevicius, Laimonas, Punab, Mari, Wang, Jinhua, Carroll, William L., Zhang, Zeyu, Dalgaard, Marlene D., Gupta, Ramneek, Nersting, Jacob, Schmiegelow, Kjeld

“…The antileukaemic drug 6-mercaptopurine is converted into thioguanine nucleotides (TGN) and incorporated into DNA (DNA-TG), the active end metabolite. In a…”
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Optimizing staining protocols for laser microdissection of specific cell types from the testis including carcinoma in situ by Sonne, Si Brask, Dalgaard, Marlene D, Nielsen, John Erik, Hoei-Hansen, Christina E, Rajpert-De Meyts, Ewa, Gjerdrum, Lise Mette, Leffers, Henrik

“…Microarray and RT-PCR based methods are important tools for analysis of gene expression; however, in tissues containing many different cells types, such as the…”
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