Search Results - "Dalfen, Richard"

Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer by KAUFMAN, Howard L, LENZ, Heinz-Josef, CONRY, Robert M, URBA, Walter J, BENSON, Al B, YU, Maria, CATERINI, Judy, KIM-SCHULZE, Seunghee, DEBENEDETTE, Mark, SALHA, Danielle, VOGEL, Thorsten, ELIAS, Ileana, MARSHALL, John, BERINSTEIN, Neil L, SINGH, Deepti, GARETT, Chris, CRIPPS, Christine, MOORE, Malcolm, VON MEHREN, Margaret, DALFEN, Richard, HEIM, William J

“…Purpose: The combination of vaccines and chemotherapy holds promise for cancer therapy, but the effect of cytotoxic chemotherapy on vaccine-induced antitumor…”
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Next-generation biobanking of metastases to enable multidimensional molecular profiling in personalized medicine by Diaz, Zuanel, Aguilar-Mahecha, Adriana, Paquet, Eric R, Basik, Mark, Orain, Michèle, Camlioglu, Errol, Constantin, André, Benlimame, Naciba, Bachvarov, Dimcho, Jannot, Guillaume, Simard, Martin J, Chabot, Benoit, Gologan, Adrian, Klinck, Roscoe, Gagnon-Kugler, Thérèse, Lespérance, Bernard, Samson, Benoit, Kavan, Petr, Alcindor, Thierry, Dalfen, Richard, Lan, Cathy, Chabot, Catherine, Buchanan, Marguerite, Przybytkowski, Ewa, Qureshi, Samia, Rousseau, Caroline, Spatz, Alan, Têtu, Bernard, Batist, Gerald

“…Great advances in analytical technology coupled with accelerated new drug development and growing understanding of biological challenges, such as tumor…”
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Reasons for delay in timely administration of adjuvant chemotherapy for patients with stage III colon cancer: a multicentre cohort study from the McGill University Department of Oncology by Elkrief, Arielle, Redstone, Genevieve, Petruccelli, Luca, Ali, Alla'a, Thomas, Doneal, Fernandez, Myriam, Rousseau, Caroline, Aleynikova, Olga, Anderson, Dawn, Ghitulescu, Gabriela, Vasilevsky, Carol-Ann, Dalfen, Richard, Langleben, Adrian, Liberman, Sender, Kavan, Petr, Alcindor, Thierry

“…PurposeAdjuvant chemotherapy within 56 or 84 days following curative resection is globally accepted as the standard of care for stage III colon cancer as it…”
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Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer by Gambaro, Karen, Marques, Maud, McNamara, Suzan, Couetoux du Tertre, Mathilde, Diaz, Zuanel, Hoffert, Cyrla, Srivastava, Archana, Hébert, Steven, Samson, Benoit, Lespérance, Bernard, Ko, Yoo‐Joung, Dalfen, Richard, St‐Hilaire, Eve, Sideris, Lucas, Couture, Felix, Burkes, Ronald, Harb, Mohammed, Camlioglu, Errol, Gologan, Adrian, Pelsser, Vincent, Constantin, André, Greenwood, Celia M.T., Tejpar, Sabine, Kavan, Petr, Kleinman, Claudia L., Batist, Gerald

“…Background Therapeutic resistance is the main cause of death in metastatic colorectal cancer. To investigate genomic plasticity, most specifically of…”
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Docetaxel-Based Neoadjuvant Chemotherapy Followed by En Bloc Resection for Esophageal Adenocarcinoma: A 15-Year Retrospective Analysis from a Regional Upper Gastrointestinal Cancer Network by Tankel, James, Ahmed, Nabeel, Mueller, Carmen, Najmeh, Sarah, Spicer, Jonathan, Mulder, David, Cool-Lartigue, Jonathan, Rousseau, Mathieu, Frechette, Dominique, Sud, Shelly, Kavan, Petr, Moghrabi, Albert, Champagne, Martin, Lemay, Frederic, Dalfen, Richard, Sirhan, Shireen, Asselah, Jamil, Alcindor, Thierry, Ferri, Lorenzo

“…Backround Real-world, long-term survival outcomes of neoadjuvant, docetaxel-based therapy for esophageal and junctional adenocarcinoma are lacking. This study…”
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Treatment sequencing in MPC, insights from a 3˚ care center by Barrera, Ivan, Ranger, Jill, Roofigari, Nooshin, Dalfen, Richard, Batist, Gerald, Kavan, Petr

“…Abstract only 400 Background: Since 2011, options for treatment of metastatic pancreatic cancer (mPC) have improved with the use of nab-paclitaxel plus…”
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A study of preoperative FOLFIRINOX in potentially curable pancreatic cancer by Javan, Hamed, Niazi, Tamim, Vanounou, Tsafrir, Pelletier, Jean-Sebastien, Dalfen, Richard, Lecavalier-Barsoum, Magali, Batist, Gerald, Kavan, Petr

“…Abstract only 719 Background: Although Folfirinox (FFX) prolonged survival in metastatic and adjuvant setting, the role of preoperative FFX is still…”
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A Pilot Randomized Controlled Trial on the Effects of a Progressive Exercise Program on the Range of Motion and Upper Extremity Grip Strength in Young Adults With Breast Cancer by Ibrahim, Marize, Muanza, Thierry, Smirnow, Nadia, Sateren, Warren, Fournier, Beatrice, Kavan, Petr, Palumbo, Michael, Dalfen, Richard, Dalzell, Mary-Ann

“…Young women with breast cancer commonly experience residual long-term arm morbidity after treatment. In the present clinical trial (n = 59), a 12-week exercise…”
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Time course of upper limb function and return-to-work post-radiotherapy in young adults with breast cancer: a pilot randomized control trial on effects of targeted exercise program by Ibrahim, Marize, Muanza, Thierry, Smirnow, Nadia, Sateren, Warren, Fournier, Beatrice, Kavan, Petr, Palumbo, Michael, Dalfen, Richard, Dalzell, Mary-Ann

“…Purpose Breast cancer (BC) diagnosis in young adults (YA) is rising, and both disease and treatments are aggressive in this population. Evidence supports the…”
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Abstract LB-231: Genomic profiling in serial metastatic colorectal tumors identifies copy number alterations and spatio temporal intra-patient heterogeneity profiles associated with clinical response. Q-CROC-01: NCT00984048 by Tertre, Mathilde Couetoux du, Marques, Maud, Gambaro, Karen, Witcher, Michael, Samson, Benoit, Lespérance, Bernard, Ko, Yoo-Joung, Dalfen, Richard, St-Hilaire, Eve, Sidéris, Lucas, Couture, Félix, Tejpar, Sabine, Burkes, Ronald, Harb, Mohammed, Camlioglu, Errol, Gologan, Adrian, Pelsser, Vincent, Constantin, André, McNamara, Suzan, Kavan, Petr, Kleinman, Claudia, Batist, Gerald

“…Abstract Introduction: Colorectal cancer (CRC) is the third leading cause of cancer related deaths primarily due to its resistance to current treatments…”
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Abstract 2795: Integrating multiomics discovery approaches to identify biomarkers of therapeutic resistance in metastatic colorectal cancer through analyses of multiple sequential tumor and liquid biopsies; Qcroc01: NCT00984048 by Gambaro, Karen, Marques, Maud, Morin, Ryan, Kleinman, Claudia, Witcher, Michael, Turcotte, Simon, Samson, Benoit, Lespérance, Bernard, Ko, Yoo-Joung, Dalfen, Richard, St-Hilaire, Eve, Sideris, Lucas, Couture, Felix, Tejpar, Sabine, Burkes, Ronald, Harb, Mohammed, Aubin, Francine, Alcindor, Thierry, Camlioglu, Errol, Aguilar, Adriana, Tertre1, Mathilde Couetoux du, McNamara, Suzan, Gologan, Adrian, Kavan, Petr, Batist, Gerald

“…Abstract Colorectal cancer (CRC) is the 2nd leading cause of cancer related-death in Canada. Clinical responses of metastatic (m)CRC to first-line treatment…”
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Abstract 3888: Molecular profiling of sequential biopsies in patients with metastatic colorectal cancer identifies genomic alterations that evolve during first-line therapy and could have therapeutic implications: A prospective study to identify molecular mechanisms of clinical resistance (QCROC-01: NCT00984048) by McNamara, Suzan, Morin, Ryan, Couëtoux du Tertre, Mathilde, McCloskey, Rosemary, Johnston, Rebecca, Fornika, Daniel, Samson, Benoit, Lespérance, Bernard, Alcindor, Thierry, Ko, Yoo-Joung, Dalfen, Richard, St-Hilaire, Eve, Sideris, Lucas, Couture, Felix, Prenen, Hans, Tejpar, Sabine, Burkes, Ronald, Constantin, André, Camlioglu, Errol, Aguilar, Adriana, Gologan, Adrian, Têtu, Benoit, Greenwood, Celia M., Hoffert, Cyrla, Qureshi, Samia, Diaz, Zuanel, Marques, Maud, Witcher, Micheal, Gagnon-Kugler, Thérèse, Kavan, Petr, Batist, Gerald

“…Abstract Therapeutic resistance remains a major obstacle in metastatic colorectal cancer (mCRC) and biomarkers to guide treatment are essential to improving…”
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Abstract 2706: Phase 2 study with pharmacokinetics (PK) analysis of sorafenib and vinorelbine in metastatic breast cancer by Ferrario, Cristiano, Miller, Wilson H., Charamis, Helen, Langleben, Adrian, Oyewole-Eletu, Shola, Dalfen, Richard, Patenaude, François, Batist, Gerald, Panasci, Lawrence C.

“…Abstract Background Sorafenib (S) is an oral inhibitor of the Raf, VEGFR and PDGFR pathways that contribute to chemoresistance in cancer cells. The combination…”
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797-2 Increased Tissue Factor at Sites of Thrombosis in an Atherosclerotic Animal Model by Johnstone, Michael T., Murillo, Jaime E., Dalfen, Richard, Daly, Tom, Pawashe, Aruna, Konigsberg, William, Ezekowitz, Michael, Quist, William, Aretz, Tom, Muller, James E., Tofler, Geoffrey H., Gurewich, Victor

“…Atherosclerotic plaque disruption and thrombosis are now recognized as major causes of acute coronary syndromes. Tissue factor may play a central role in…”
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Further experience with regional radiofrequency hyperthermia and cytotoxic chemotherapy for unresectable hepatic neoplasia by Moffat, F L, Gilas, T, Calhoun, K, Falk, M, Dalfen, R, Rotstein, L E, Makowka, L, Howard, V, Laing, D, Venturi, D

“…The authors report on 178 patients with unresectable hepatic tumors who have been treated with 1 to 25 (median, 6) courses of radiofrequency hyperthermia…”
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Radiofrequency hyperthermia as adjuvant therapy following surgical resection of an experimental malignant neoplasm by Dalfen, R, Calhoun, K, Gilas, T, Mathews, T, Falk, M, Moffat, F L, Makowka, L, Rotstein, L E, Langer, J C, Venturi, D

“…Local recurrence after radical surgery is a major problem with many primary solid cancers. The use of radiofrequency hyperthermia (RFHT) as adjuvant therapy to…”
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Reversal of cyclosporine-induced mortality with a synthetic polymeric immunostimulant in a murine model of fecal peritonitis by Moffat, F L, Falk, R E, Teodorczyk-Injeyan, J, Clark, A G, Gilas, T, Falk, M, Dalfen, R, Rotstein, L E, McDonell, M, Makowka, L

“…We have been investigating the effects of a synthetic immunostimulative polymer known as copovithane (Cpv). This agent appears to enhance humoral immunity in…”
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