Search Results - "Daley, John"

Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma by Prabhala, Rao H., Pelluru, Dheeraj, Fulciniti, Mariateresa, Prabhala, Harsha K., Nanjappa, Puru, Song, Weihua, Pai, Christine, Amin, Samir, Tai, Yu-Tzu, Richardson, Paul G., Ghobrial, Irene M., Treon, Steven P., Daley, John F., Anderson, Kenneth C., Kutok, Jeffery L., Munshi, Nikhil C.

“…Elevated cytokines in bone marrow (BM) micro-environment (interleukin-6 [IL-6], transforming growth factor-beta [TGF-β], and IL-1β) may play an important role…”
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Reversible resistance induced by FLT3 inhibition: a novel resistance mechanism in mutant FLT3-expressing cells by Weisberg, Ellen, Ray, Arghya, Nelson, Erik, Adamia, Sophia, Barrett, Rosemary, Sattler, Martin, Zhang, Chengsheng, Daley, John F, Frank, David, Fox, Edward, Griffin, James D

“…Clinical responses achieved with FLT3 kinase inhibitors in acute myeloid leukemia (AML) are typically transient and partial. Thus, there is a need for…”
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Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications by Jakubikova, Jana, Adamia, Sophia, Kost-Alimova, Maria, Klippel, Steffen, Cervi, David, Daley, John F., Cholujova, Dana, Kong, Sun-Young, Leiba, Merav, Blotta, Simona, Ooi, Melissa, Delmore, Jake, Laubach, Jacob, Richardson, Paul G., Sedlak, Jan, Anderson, Kenneth C., Mitsiades, Constantine S.

“…Recurrence of multiple myeloma (MM) after therapy suggests the presence of tumor-initiating subpopulations. In our study, we performed flow cytometry–based…”
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SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma by Chen, Linfeng, Monti, Stefano, Juszczynski, Przemyslaw, Daley, John, Chen, Wen, Witzig, Thomas E., Habermann, Thomas M., Kutok, Jeffery L., Shipp, Margaret A.

“…The role of B-cell receptor (BCR)–mediated survival signals in diffuse large B-cell lymphoma (DLBCL) remains undefined. Ligand-induced BCR signaling induces…”
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Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase by Weisberg, Ellen L, Puissant, Alexandre, Stone, Richard, Sattler, Martin, Buhrlage, Sara J, Yang, Jing, Manley, Paul W, Meng, Chengcheng, Buonopane, Michael, Daley, John F, Lazo, Suzan, Wright, Renee, Weinstock, David M, Christie, Amanda L, Stegmaier, Kimberly, Griffin, James D

“…Oncogenic FLT3 kinase is a clinically validated target in acute myeloid leukemia (AML), and both multi-targeted and selective FLT3 inhibitors have been…”
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Dysfunctional T regulatory cells in multiple myeloma by Prabhala, Rao H., Neri, Paola, Bae, Jooeun E., Tassone, Pierfrancesco, Shammas, Masood A., Allam, Charles K., Daley, John F., Chauhan, Dharminder, Blanchard, Elizabeth, Thatte, Hemant S., Anderson, Kenneth C., Munshi, Nikhil C.

“…Multiple myeloma (MM) is characterized by the production of monoclonal immunoglobulin and is associated with suppressed uninvolved immunoglobulins and…”
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Immune profiling of age and adjuvant-specific activation of human blood mononuclear cells in vitro by Schüller, Simone S., Barman, Soumik, Mendez-Giraldez, Raul, Soni, Dheeraj, Daley, John, Baden, Lindsey R., Levy, Ofer, Dowling, David J.

“…Vaccination reduces morbidity and mortality due to infections, but efficacy may be limited due to distinct immunogenicity at the extremes of age. This raises…”
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Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma by JAKUBIKOVA, Jana, CERVI, David, NEGRI, Joseph, BLOTTA, Simona, MCMILLIN, Douglas W, HIDESHIMA, Teru, RICHARDSON, Paul G, SEDLAK, Jan, ANDERSON, Kenneth C, MITSIADES, Constantine S, OOI, Melissa, KIM, Kihyun, NAHAR, Sabikun, KLIPPEL, Steffen, CHOLUJOVA, Dana, LEIBA, Merav, DALEY, John F, DELMORE, Jake

“…Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a…”
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Fiscal challenges for Australia: The next decade and beyond by Daley, John, Wood, Danielle

“…In Australia, both the Commonwealth and state governments are running substantial budget deficits, and future challenges are likely to make these problems…”
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Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells by Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alex K., Bandopadhayay, Pratiti, Beroukhim, Rameen

“…Pilocytic astrocytoma (PA), the most common childhood brain tumor, is a low-grade glioma with a single driver BRAF rearrangement. Here, we perform scRNAseq in…”
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Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenström macroglobulinemia by Moreau, Anne-Sophie, Jia, Xiaoying, Ngo, Hai T., Leleu, Xavier, O'Sullivan, Garrett, Alsayed, Yazan, Leontovich, Alexey, Podar, Klaus, Kutok, Jeffrey, Daley, John, Lazo-Kallanian, Suzan, Hatjiharissi, Evdoxia, Raab, Marc S., Xu, Lian, Treon, Steven P., Hideshima, Teru, Anderson, Kenneth C., Ghobrial, Irene M.

“…Waldenström macroglobulinemia (WM) is an incurable lymphoplasmacytic lymphoma with limited options of therapy. Protein kinase Cβ (PKCβ) regulates cell survival…”
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Remote access technology offers tremendous possibilities to the cytometry community by Moran, Barry, Blanco‐Fernández, Alfonso, Gardner, Rui, Tigges, John, Toxavidis, Vasilis, Daley, John F.

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Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells by Weisberg, Ellen, Roesel, Johannes, Bold, Guido, Furet, Pascal, Jiang, Jingrui, Cools, Jan, Wright, Renee D., Nelson, Erik, Barrett, Rosemary, Ray, Arghya, Moreno, Daisy, Hall-Meyers, Elizabeth, Stone, Richard, Galinsky, Ilene, Fox, Edward, Gilliland, Gary, Daley, John F., Lazo-Kallanian, Suzan, Kung, Andrew L., Griffin, James D.

“…An attractive target for therapeutic intervention is constitutively activated, mutant FLT3, which is expressed in a subpopulation of patients with acute…”
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Measles Virus Infection Induces Chemokine Synthesis by Neurons by Patterson, Catherine E, Daley, John K, Echols, Lisa A, Lane, Thomas E, Rall, Glenn F

“…The role that neurons play in the induction of the immune response following CNS viral infection is poorly understood, largely owing to the belief that these…”
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Characterization of mold fouling during elastomer injection molding by Hornsby, Peter R., Singh, Inderjeet, Daley, John R., Firth, John

“…Consideration is given to the characterization and origins of mold fouling occurring during the injection molding of elastomers. Results for nitrile rubber and…”
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Poliovirus replication and spread in primary neuron cultures by Daley, John K., Gechman, Lisa A., Skipworth, Jason, Rall, Glenn F.

“…While some neurotropic viruses cause rapid central nervous system (CNS) disease upon entry into the brain parenchyma, other viruses that are cytolytic in the…”
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Fort Dudley: Doing Public History Before Public History was Cool by Daley, John

“…Daley revisits the legacy of writer Dudley Taylor Cornish in developing the field of public history. Dudley played indispensable roles in helping a former…”
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Neuronal Survival Strategies in the Face of RNA Viral Infection by Patterson, Catherine E., Daley, John K., Rall, Glenn F.

“…Neurons of the mammalian central nervous system (CNS) are an essential and largely nonrenewable cell population. Thus, viral infections that result in neuronal…”
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Paraphrasing a Predicament: Operation Iraqi Freedom and the Mesopotamian Insurrection of 1920 by Daley, John

“…Daley discusses the important lessons from Operation Iraqi Freedom and the Mesopotamian insurrection of 1920. He cites that as in 1920, the most important…”
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Access all areas by Daley, John, Shiu, Alicia

“…A life science business plan competition designed to catalyze young bioentrepreneurs shows the way for other regions seeking to galvanize biotech startups…”
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