Search Results - "Dalemans, Wilfried"

Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single‐Blind, Parallel Group, Placebo Controlled Trial by Perlee, Desiree, van Vught, Lonneke A., Scicluna, Brendon P., Maag, Anja, Lutter, René, Kemper, Elles M., van ‘t Veer, Cornelis, Punchard, Marie A., González, Jesús, Richard, Marie Paule, Dalemans, Wilfried, Lombardo, Eleuterio, de Vos, Alex F., van der Poll, Tom

“…In experimental models, mesenchymal stem cells (MSCs) can modulate various immune responses implicated in the pathogenesis of sepsis. Intravenous injection of…”
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Survival and biodistribution of xenogenic adipose mesenchymal stem cells is not affected by the degree of inflammation in arthritis by Toupet, Karine, Maumus, Marie, Luz-Crawford, Patricia, Lombardo, Eleuterio, Lopez-Belmonte, Juan, van Lent, Peter, Garin, Marina I, van den Berg, Wim, Dalemans, Wilfried, Jorgensen, Christian, Noël, Danièle

“…Application of mesenchymal stem/stromal cells (MSCs) in treating different disorders, in particular osteo-articular diseases, is currently under investigation…”
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Mesenchymal stem cells as a therapeutic tool to treat sepsis by Lombardo, Eleuterio, van der Poll, Tom, DelaRosa, Olga, Dalemans, Wilfried

“…Sepsis is a clinical syndrome caused by a deregulatedhost response to an infection. Sepsis is the mostfrequent cause of death in hospitalized patients.Although…”
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Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2 by Ortiz-Virumbrales, Maitane, Menta, Ramón, Pérez, Laura M, Lucchesi, Ornella, Mancheño-Corvo, Pablo, Avivar-Valderas, Álvaro, Palacios, Itziar, Herrero-Mendez, Angel, Dalemans, Wilfried, de la Rosa, Olga, Lombardo, Eleuterio

“…Mesenchymal stem cells (MSCs) activate the endogenous immune regulatory system, inducing a therapeutic effect in recipients. MSCs have demonstrated the ability…”
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Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae by Perlee, Desiree, Vos, Alex F., Scicluna, Brendon P., Mancheño, Pablo, Rosa, Olga, Dalemans, Wilfried, Nürnberg, Peter, Lombardo, Eleuterio, Poll, Tom

“…Adult mesenchymal stem cells exert immunomodulatory effects that might improve the host response during sepsis. Knowledge on the effect of adipose‐derived…”
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Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients by Avivar-Valderas, Alvaro, Martín-Martín, Cristina, Ramírez, Cristina, Del Río, Borja, Menta, Ramón, Mancheño-Corvo, Pablo, Ortiz-Virumbrales, Maitane, Herrero-Méndez, Ángel, Panés, Julián, García-Olmo, Damián, Castañer, José Luís, Palacios, Itziar, Lombardo, Eleuterio, Dalemans, Wilfried, DelaRosa, Olga

“…Adipose mesenchymal stem cells (ASC) are considered minimally immunogenic. This is due to the low expression of human leukocyte antigens I (HLA-I), lack of…”
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Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys by Reed, Steven G, Coler, Rhea N, Dalemans, Wilifred, Tan, Esterlina V, DeLa Cruz, Eduardo C, Basaraba, Randall J, Orme, Ian M, Skeiky, Yasir A.W, Alderson, Mark R, Cowgill, Karen D, Prieels, Jean-Paul, Abalos, Rodolfo M, Dubois, Marie-Claude, Cohen, Joe, Mettens, Pascal, Lobet, Yves

“…The development of a vaccine for tuberculosis requires a combination of antigens and adjuvants capable of inducing appropriate and long-lasting T cell…”
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Comparative Analysis between the In Vivo Biodistribution and Therapeutic Efficacy of Adipose-Derived Mesenchymal Stromal Cells Administered Intraperitoneally in Experimental Colitis by Lopez-Santalla, Mercedes, Mancheño-Corvo, Pablo, Escolano, Amelia, Menta, Ramon, Delarosa, Olga, Redondo, Juan M, Bueren, Juan A, Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I

“…Mesenchymal stem cells (MSCs) have emerged as a promising treatment for inflammatory diseases. The immunomodulatory effect of MSCs takes place both by direct…”
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Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice by Perlee, Desirée, de Vos, Alex F, Scicluna, Brendon P, Maag, Anja, Mancheño, Pablo, de la Rosa, Olga, Dalemans, Wilfried, Florquin, Sandrine, Van't Veer, Cornelis, Lombardo, Eleuterio, van der Poll, Tom

“…Adult mesenchymal stem cells (MSCs) improve the host response during experimental sepsis in animals. MSCs from various sources express a procoagulant activity…”
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Differential Immune Responses and Protective Efficacy Induced by Components of a Tuberculosis Polyprotein Vaccine, Mtb72F, Delivered as Naked DNA or Recombinant Protein by Skeiky, Yasir A. W, Alderson, Mark R, Ovendale, Pamela J, Guderian, Jeffrey A, Brandt, Lise, Dillon, Davin C, Campos-Neto, Antonio, Lobet, Yves, Dalemans, Wilfried, Orme, Ian M, Reed, Steven G

“…Key Ags of Mycobacterium tuberculosis initially identified in the context of host responses in healthy purified protein derivative-positive donors and infected…”
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Human cardiac stem cells inhibit lymphocyte proliferation through paracrine mechanisms that correlate with indoleamine 2,3-dioxygenase induction and activity by Sebastião, Maria J, Menta, Ramón, Serra, Margarida, Palacios, Itziar, Alves, Paula M, Sanchez, Belén, DelaRosa, Olga, Dalemans, Wilfried, Lombardo, Eleuterio, Gomes-Alves, Patrícia

“…Transplantation of allogeneic human cardiac/stem progenitor cells (hCSCs) is currently being tested in several phase I/II clinical trials as a novel and…”
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Intralymphatic Administration of Adipose Mesenchymal Stem Cells Reduces the Severity of Collagen-Induced Experimental Arthritis by Mancheño-Corvo, Pablo, Lopez-Santalla, Mercedes, Menta, Ramon, DelaRosa, Olga, Mulero, Francisca, Del Rio, Borja, Ramirez, Cristina, Büscher, Dirk, Bueren, Juan A, Lopez-Belmonte, Juan, Dalemans, Wilfried, Garin, Marina I, Lombardo, Eleuterio

“…Mesenchymal stem cells (MSCs) are multipotent stromal cells with immunomodulatory properties. They have emerged as a very promising treatment for autoimmunity…”
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Human Cardiac-Derived Stem/Progenitor Cells Fine-Tune Monocyte-Derived Descendants Activities toward Cardiac Repair by Dam, Noémie, Hocine, Hocine Rachid, Palacios, Itziar, DelaRosa, Olga, Menta, Ramón, Charron, Dominique, Bensussan, Armand, El Costa, Hicham, Jabrane-Ferrat, Nabila, Dalemans, Wilfried, Lombardo, Eleuterio, Al-Daccak, Reem

“…Cardiac repair following MI relies on a finely regulated immune response involving sequential recruitment of monocytes to the injured tissue. Monocyte-derived…”
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Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis by Lopez-Santalla, Mercedes, Mancheño-Corvo, Pablo, Escolano, Amelia, Menta, Ramon, DelaRosa, Olga, Abad, Jose Luis, Büscher, Dirk, Redondo, Juan M, Bueren, Juan A, Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I

“…Mesenchymal stem cells (MSCs) have a large potential in cell therapy for treatment of inflammatory and autoimmune diseases, thanks to their immunomodulatory…”
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Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6 by Langermans, Jan A.M., Doherty, T. Mark, Vervenne, Richard A.W., Laan, Tridia van der, Lyashchenko, Konstantin, Greenwald, Rena, Agger, Else Marie, Aagaard, Claus, Weiler, Horst, Soolingen, Dick van, Dalemans, Wilfried, Thomas, Alan W., Andersen, Peter

“…Various new tuberculosis (TB) vaccine candidates in combination with new delivery systems, including subunit vaccines, are currently being evaluated by a…”
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The Protective Effect of the Mycobacterium bovis BCG Vaccine Is Increased by Coadministration with the Mycobacterium tuberculosis 72-Kilodalton Fusion Polyprotein Mtb72F in M. tuberculosis-Infected Guinea Pigs by BRANDT, Lise, SKEIKY, Yasir A. W, REED, Steven G, ORME, Ian M, ALDERSON, Mark R, LOBET, Yves, DALEMANS, Wilfried, TURNER, Oliver C, BASARABA, Randall J, IZZO, Angelo A, LASCO, Todd M, CHAPMAN, Philip L

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Adipose‐derived mesenchymal stromal cells modulate experimental autoimmune arthritis by inducing an early regulatory innate cell signature by Lopez‐Santalla, Mercedes, Menta, Ramon, Mancheño‐Corvo, Pablo, Lopez‐Belmonte, Juan, DelaRosa, Olga, Bueren, Juan A., Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I.

“…Modulation of innate immune responses in rheumatoid arthritis and other immune‐mediated disorders is of critical importance in the clinic since a growing body…”
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Improved Immunogenicity and Protective Efficacy of a Tuberculosis DNA Vaccine Encoding Ag85 by Protein Boosting by TANGHE, Audrey, D'SOUZA, Sushila, ROSSEELS, Valérie, DENIS, Olivier, OTTENHOFF, Thomas H. M, DALEMANS, Wilfried, WHEELER, Carl, HUYGEN, Kris

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Evaluation of the Mtb72F Polyprotein Vaccine in a Rabbit Model of Tuberculous Meningitis by TSENOVA, Liana, HARBACHEUSKI, Ryhor, MOREIRA, Andre L, ELLISON, Evette, DALEMANS, Wilfried, ALDERSON, Mark R, MATHEMA, Barun, REED, Steven G, SKEIKY, Yasir A. W, KAPLAN, Gilla

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In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium by Rosenfeld, M A, Yoshimura, K, Trapnell, B C, Yoneyama, K, Rosenthal, E R, Dalemans, W, Fukayama, M, Bargon, J, Stier, L E, Stratford-Perricaudet, L

“…Direct transfer of the normal cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene to airway epithelium was evaluated using a…”
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