Search Results - "Dalel, J."
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Development of a sensitive, quantitative assay with broad subtype specificity for detection of total HIV-1 nucleic acids in plasma and PBMC
Published in Scientific reports (28-01-2022)“…An LTR-based quantitative PCR (qPCR) assay was modified and optimized for the quantification of total HIV-1 nucleic acids in plasma and PBMC. TaqMan qPCR…”
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HIV-1 infection and the control of viral replication are associated with greater expression of interleukin-21 receptor on CD8+ T cells
Published in Journal of the International AIDS Society (01-01-2021)“…Background: Interleukin-21 plays an important role in the development of the immune response where it has been linked with the generation of virus-specific…”
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Spontaneous in vivo control of HIV replication is underpinned by the cross-clade antiviral potency of HIV-specific CD8 T cells
Published in Journal of the International AIDS Society (01-01-2021)“…Background: CD8 T cells are critical in the resolution of acute HIV viraemia and long term spontaneous persistent virus control. Obtaining a better…”
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Analysis of the early responses to HIV-1 in matched treatment naive individuals reveals early soluble proteins that are associated with in vivo virus control
Published in Journal of the International AIDS Society (01-01-2021)“…Background: In attempting to define the correlates associated with natural protection against HIV, extreme heterogeneity in the datasets generated from systems…”
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Journal Article