Search Results - "Dale Thurman, J."
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Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys
Published in Toxicology and applied pharmacology (01-12-2017)“…Multiplex biomarker panel assays would enable early de-risking of discovery compound related kidney safety liabilities. The objective of this study was to…”
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DP-2Ø2216-6 maize does not adversely affect rats in a 90-day feeding study
Published in Regulatory toxicology and pharmacology (01-11-2020)“…Maize plants containing event DP-2Ø2216-6 (DP202216), which confers herbicide tolerance through expression of phosphinothricin acetyltransferase and enhanced…”
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Survival, body weight, and spontaneous neoplasms in ad Libitum-fed and food-restricted Fischer-344 rats
Published in Toxicologic pathology (01-01-1994)“…Ad libitum-fed (AL) and food-restricted (FR) Fischer-344 male and female rats were monitored for survival, body weight, and spontaneous neoplasms. Mean and…”
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The mycotoxin fumonisin induces apoptosis in cultured human cells and in livers and kidneys of rats
Published in Advances in experimental medicine and biology (1996)“…Fumonisin B1 is a mycotoxin produced by Fusarium moniliforme, a fungus that infects corn and other grains in the U.S. Fumonisin ingestion causes a variety of…”
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Genome-linked toxic responses to dietary iron overload
Published in Toxicologic pathology (01-11-1997)“…Genome-related differences to Fe overload between and within rodent species were evaluated in the present study. Male B6C3F1 mice, yellow and black C5YSF1…”
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Oral squamous cell carcinoma in ad libitum-fed and food-restricted Brown-Norway rats
Published in Toxicologic pathology (01-03-1997)“…A high incidence of oral squamous cell carcinoma was present in male and female Brown-Norway rats fed ad libitum or food-restricted dietary formulations. One…”
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Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat
Published in Environmental health perspectives (01-05-2001)“…Fumonisin B1(FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies…”
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Compensatory Regeneration as a Mechanism for Renal Tubule Carcinogenesis of Fumonisin B1in the F344/N/Nctr BR Rat
Published in Environmental health perspectives (01-05-2001)“…Fumonisin B1( FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies…”
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Compensatory Regeneration as a Mechanism for Renal Tubule Carcinogenesis of Fumonisin B 1 in the F344/N/Nctr BR Rat
Published in Environmental health perspectives (01-05-2001)Get full text
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