Search Results - "Dale, Timothy"
-
1
LIVECell—A large-scale dataset for label-free live cell segmentation
Published in Nature methods (01-09-2021)“…Light microscopy combined with well-established protocols of two-dimensional cell culture facilitates high-throughput quantitative imaging to study biological…”
Get full text
Journal Article -
2
Radical Reimagining for Student Success in Higher Education
Published in Stylus Publishing LLC (27-04-2023)“…Co-published with the Association for State Colleges and Universities (AASCU), which sponsored the project from which the book emerged. This book answers the…”
Get more information
Book -
3
Beyond mean pharyngeal constrictor dose for beam path toxicity in non-target swallowing muscles: Dose–volume correlates of chronic radiation-associated dysphagia (RAD) after oropharyngeal intensity modulated radiotherapy
Published in Radiotherapy and oncology (01-02-2016)“…Abstract Purpose/objective(s) We sought to identify swallowing muscle dose–response thresholds associated with chronic radiation-associated dysphagia (RAD)…”
Get full text
Journal Article -
4
The drivers of squirrelpox virus dynamics in its grey squirrel reservoir host
Published in Epidemics (01-09-2019)“…[Display omitted] •Squirrelpox virus (SQPV) is a chronic infection in >80% of individual grey squirrels.•Longitudinal data shows SQPV infection commonly recurs…”
Get full text
Journal Article -
5
Hemophilic arthropathy of the elbow: prophylaxis, imaging, and the role of invasive management
Published in Journal of shoulder and elbow surgery (01-10-2015)“…Hemophilia is an X-linked recessive deficiency of clotting factor VIII (hemophilia A) or IX (hemophilia B) that can result in hemarthrosis of various joints,…”
Get full text
Journal Article -
6
European red squirrel population dynamics driven by squirrelpox at a gray squirrel invasion interface
Published in Ecology and evolution (01-10-2014)“…Infectious disease introduced by non‐native species is increasingly cited as a facilitator of native population declines, but direct evidence may be lacking…”
Get full text
Journal Article -
7
The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy
Published in EMBO molecular medicine (01-09-2014)“…Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including preterm birth, dysfunctional labour and post‐partum…”
Get full text
Journal Article -
8
Chronic radiation-associated dysphagia in oropharyngeal cancer survivors: Towards age-adjusted dose constraints for deglutitive muscles
Published in Clinical and translational radiation oncology (01-09-2019)“…•Age at treatment for OPSCC is a strong predictor of chronic radiation associated dysphagia (RAD).•For swallowing regions of interest (ROIs), dose to ROI and…”
Get full text
Journal Article -
9
Enhancement of wildlife disease surveillance using multiplex quantitative PCR: development of qPCR assays for major pathogens in UK squirrel populations
Published in European journal of wildlife research (01-10-2016)“…Rapid development in polymerase chain reaction (PCR) technology has revolutionised the speed and accuracy of many diagnostic assays. However, comparatively few…”
Get full text
Journal Article -
10
The Sodium Channel β3-Subunit Induces Multiphasic Gating in NaV1.3 and Affects Fast Inactivation via Distinct Intracellular Regions
Published in The Journal of biological chemistry (22-10-2010)“…Electrical excitability in neurons depends on the activity of membrane-bound voltage gated sodium channels (Nav) that are assembled from an ion conducting…”
Get full text
Journal Article -
11
Cloning, distribution and functional analysis of the type III sodium channel from human brain
Published in The European journal of neuroscience (01-12-2000)“…The type III voltage‐gated sodium channel was cloned from human brain. The full‐length cDNA has 89% identity with rat type III, and the predicted protein (1951…”
Get full text
Journal Article -
12
Cloning, distribution and functional analysis of the type III sodium channel from human brain
Published in The European journal of neuroscience (01-12-2000)“…The type III voltage-gated sodium channel was cloned from human brain. The full-length cDNA has 89% identity with rat type III, and the predicted protein (1951…”
Get full text
Journal Article -
13
Electrophysiological and pharmacological properties of the human brain type IIA Na+ channel expressed in a stable mammalian cell line
Published in Pflügers Archiv (01-01-2001)“…The human brain voltage-gated Na+ channel type IIA alpha subunit was cloned and stably expressed in Chinese hamster ovary cells and its biophysical and…”
Get full text
Journal Article -
14
High-throughput Quantification of Antibody-Dependent Phagocytosis using Live-Cell Analysis
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract The uptake and clearance of tumor cells can be promoted with monoclonal antibodies (mAbs) via antibody-dependent phagocytosis (ADCP) or through the…”
Get full text
Journal Article -
15
Abstract 311: Phenotyping tumor infiltrating lymphocytes (TILs) in vitro using 3D cell models and advanced flow cytometry
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract The importance of the immune system in cancer treatment is now recognized with a range of therapies utilizing its power to more effectively target…”
Get full text
Journal Article -
16
Evaluation of checkpoint inhibitor therapies using a mixed lymphocyte reaction (MLR) assay
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract Checkpoint inhibitors block the ‘off’ signals that are engaged when T cells interact with antigen-presenting cells, such as dendritic cells (DCs)…”
Get full text
Journal Article -
17
Anti-emetic profile of a non-peptide neurokinin NK1 receptor antagonist, CP-99,994, in ferrets
Published in European journal of pharmacology (02-11-1993)“…In the ferret, 5-HT3 receptor antagonists are effective in controlling emesis produced by cytotoxic agents or radiation. To investigate the possibility that…”
Get more information
Journal Article -
18
MRI-Ultrasound Fused Approach for Prostate Biopsy-How It Is Performed
Published in Cancers (01-04-2024)“…The use of MRI-ultrasound image fusion targeted biopsy of the prostate in the face of an elevated serum PSA is now recommended by multiple societies, and…”
Get full text
Journal Article -
19
Abstract 1305: Classification of cell morphology using machine learning and label-free live-cell imaging
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Cell morphology is incredibly diverse and provides valuable insight into cellular dynamics, including cell health and differentiation. For ease of…”
Get full text
Journal Article -
20
Abstract 5418: AI-driven image analysis enables simplified, label-free cytotoxicity screening
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract The increasing use of precious, patient-derived cells has driven the need for non-perturbing and label-free cell measurements, particularly in the…”
Get full text
Journal Article