Search Results - "Dale, Rodney M."
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Identification of an evolutionarily conserved regulatory element of the zebrafish col2a1a gene
Published in Developmental biology (15-09-2011)“…Zebrafish ( Danio rerio) is an excellent model organism for the study of vertebrate development including skeletogenesis. Studies of mammalian cartilage…”
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Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development
Published in Development (Cambridge) (01-05-2018)“…Zebrafish mutants with increased retinoic acid (RA) signaling due to the loss of the RA-inactivating enzyme Cyp26b1 develop a hyper-mineralized spine with…”
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Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations
Published in Developmental biology (01-02-2014)“…Congenital vertebral malformations (CVM) occur in 1 in 1000 live births and in many cases can cause spinal deformities, such as scoliosis, and result in…”
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Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair
Published in eLife (06-02-2018)“…Regenerative therapy for degenerative spine disorders requires the identification of cells that can slow down and possibly reverse degenerative processes…”
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Planar cell polarity signaling in craniofacial development
Published in Organogenesis (01-10-2011)“…Out of the several signaling pathways controlling craniofacial development, the role of planar cell polarity (PCP) signaling is relatively poorly understood…”
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A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis
Published in Mechanisms of development (01-11-2015)“…The Wnt/Planar Cell Polarity (PCP) pathway controls cell morphology and behavior during animal development. Several zebrafish mutants were identified as having…”
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Zebrafish: modeling for herpes simplex virus infections
Published in Zebrafish (01-02-2014)“…For many years, zebrafish have been the prototypical model for studies in developmental biology. In recent years, zebrafish has emerged as a powerful model…”
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Expression and characterization of the zebrafish orthologue of the human FOLR1 gene during embryogenesis
Published in Gene Expression Patterns (01-11-2017)“…It has been well established that many types of rapidly dividing normal and diseased cells require an increased amount of folate for DNA replication and repair…”
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The emerging role of Wnt/PCP signaling in organ formation
Published in Zebrafish (01-03-2009)“…Over the last two decades zebrafish has been an excellent model organism to study vertebrate development. Mutant analysis combined with gene knockdown and…”
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An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif
Published in Biochemical and biophysical research communications (08-06-2007)“…The FOG family of transcriptional co-factors is composed of two members in mammals: FOG-1 and FOG-2. Both have been shown to bind to GATA factors and function…”
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