Search Results - "Dale, Nicole"

P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke by Eltom, Suffwan, Stevenson, Christopher S, Rastrick, Joseph, Dale, Nicole, Raemdonck, Kristof, Wong, Sissie, Catley, Matthew C, Belvisi, Maria G, Birrell, Mark A

“…Chronic Obstructive Pulmonary Disease (COPD) is a cigarette smoke (CS)-driven inflammatory airway disease with an increasing global prevalence. Currently there…”
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Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD by Eltom, Suffwan, Dale, Nicole, Raemdonck, Kristof R G, Stevenson, Christopher S, Snelgrove, Robert J, Sacitharan, Pradeep K, Recchi, Chiara, Wavre-Shapton, Silene, McAuley, Daniel F, O'Kane, Cecilia, Belvisi, Maria G, Birrell, Mark A

“…Infection-related exacerbations of respiratory diseases are a major health concern; thus understanding the mechanisms driving them is of paramount importance…”
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Bronchodilator activity of bitter tastants in human tissue by Belvisi, Maria G, Dale, Nicole, Birrell, Mark A, Canning, Brendan J

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CD4⁺ and CD8⁺ T cells play a central role in a HDM driven model of allergic asthma by Raemdonck, Kristof, Baker, Katie, Dale, Nicole, Dubuis, Eric, Shala, Fisnik, Belvisi, Maria G, Birrell, Mark A

“…The incidence of asthma is increasing at an alarming rate and while the current available therapies are effective in the majority of patients they fail to…”
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Selectivity profiling of the novel EP2 receptor antagonist, PF‐04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor by Birrell, Mark A, Maher, Sarah A, Buckley, James, Dale, Nicole, Bonvini, Sara, Raemdonck, Kristof, Pullen, Nick, Giembycz, Mark A, Belvisi, Maria G

“…BACKGROUND AND PURPOSE Understanding the role of the EP2 receptor has been hampered by the lack of a selective antagonist. Recently, a selective EP2 receptor…”
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Bronchodilator activity of bitter tastants in human tissue by Deshpande, Deepak A, Robinett, Kathryn S, Wang, Wayne C H, Sham, James S K, An, Steven S, Liggett, Stephen B

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The role of adenylyl cyclase isoform 6 in [beta]-adrenoceptor signalling in murine airways by Birrell, Mark A, Bonvini, Sara J, Wortley, Michael A, Buckley, James, Yew-Booth, Liang, Maher, Sarah A, Dale, Nicole, Dubuis, Eric D, Belvisi, Maria G

“…Background and Purpose Adenylyl cyclase (AC) is a key signalling enzyme for many GPCRs and catalyses the conversion of ATP to cAMP which, in turn, is a crucial…”
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The role of adenylyl cyclase isoform 6 in β‐adrenoceptor signalling in murine airways by Birrell, Mark A, Bonvini, Sara J, Wortley, Michael A, Buckley, James, Yew‐Booth, Liang, Maher, Sarah A, Dale, Nicole, Dubuis, Eric D, Belvisi, Maria G

“…Background and Purpose Adenylyl cyclase (AC) is a key signalling enzyme for many GPCRs and catalyses the conversion of ATP to cAMP which, in turn, is a crucial…”
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Bronchodilator activity of bitter tastants in human tissue by Belvisi, Maria G, Dale, Nicole, Birrell, Mark A, Canning, Brendan J

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Selectivity profiling of the novel EP 2 receptor antagonist, PF‐04418948, in functional bioassay systems: atypical affinity at the guinea pig EP 2 receptor by Birrell, Mark A, Maher, Sarah A, Buckley, James, Dale, Nicole, Bonvini, Sara, Raemdonck, Kristof, Pullen, Nick, Giembycz, Mark A, Belvisi, Maria G

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Studying the effect of cigarette smoke exposure on murine models of allergic asthma by Dale, Nicole

“…Exposure to pollution and active or passive smoking have been associated with a worsened asthma severity and a reduced response to treatment. These poorly…”
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An evaluation of the short-term influence of Lock Haven University's Upward Bound program by Chartas, Nicole Dale

“…The present investigation addressed the influence of Lock Haven University of Pennsylvania's Upward Bound program on participants' standardized test scores as…”
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