Search Results - "Dale, G E"

Pharmacokinetics and Pharmacodynamics of Murepavadin in Neutropenic Mouse Models by Melchers, M J, Teague, J, Warn, P, Hansen, J, Bernardini, F, Wach, A, Obrecht, D, Dale, G E, Mouton, J W

“…Murepavadin (POL7080) represents the first member of a novel class of outer membrane protein-targeting antibiotics. It specifically interacts with LptD and…”
Get full text

Pharmacokinetic-Pharmacodynamic Evaluation of Ertapenem for Patients with Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia by Bader, J C, Lakota, E A, Dale, G E, Sader, H S, Rex, J H, Ambrose, P G, Bhavnani, S M

“…Ertapenem provides activity against many pathogens commonly associated with hospital-acquired and ventilator-associated bacterial pneumoniae (HABP and VABP,…”
Get full text

Structure-activity relationships of actively FhuE transported rifabutin derivatives with potent activity against Acinetobacter baumannii by Maingot, M., Bourotte, M., Vetter, A.C., Schellhorn, B., Antraygues, K., Scherer, H., Gitzinger, M., Kemmer, C., Dale, G.E., Defert, O., Lociuro, S., Brönstrup, M., Willand, N., Trebosc, V.

“…Hospital-acquired infections are on the rise and represent both, a clinical and financial burden. With resistance emerging and an ever-dwindling armamentarium…”
Get full text

Roles of Aconitase in Growth, Metabolism, and Morphological Differentiation of Streptomyces coelicolor by Viollier, P H, Nguyen, K T, Minas, W, Folcher, M, Dale, G E, Thompson, C J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP) by Bur, Daniel, Dale, Glenn E., Oefner, Christian

“…Endothelin-converting enzyme 1 (ECE-1, EC 3.4.24.71) is a zinc-dependent type II mammalian membrane protein comprising the active site in the ectodomain. It…”
Get full text

Cloning and characterization of a novel, plasmid-encoded trimethoprim-resistant dihydrofolate reductase from Staphylococcus haemolyticus MUR313 by DALE, G. E, LANGEN, H, PAGE, M. G. P, THEN, R. L, STÜBER, D

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

Characterization of the gene for the chromosomal dihydrofolate reductase (DHFR) of Staphylococcus epidermidis ATCC 14990: the origin of the trimethoprim-resistant S1 DHFR from Staphylococcus aureus? by Dale, G E, Broger, C, Hartman, P G, Langen, H, Page, M G, Then, R L, Stüber, D

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Unconventional neutron sources for oil well logging by Frankle, C.M., Dale, G.E.

“…Americium–Beryllium (AmBe) radiological neutron sources have been widely used in the petroleum industry for well logging purposes. There is strong desire on…”
Get full text

Investigation of the Piezoelectric Effect as a Means to Generate X-Rays by Gall, B., Kovaleski, S. D., VanGordon, J. A., Norgard, P., Benwell, A., Kim, B. H., Kwon, J. W., Dale, G. E.

“…The piezoelectric effect is analyzed as a means to produce X-rays. A mass of crystalline piezoelectric material is used to convert a low-voltage input…”
Get full text

A Test Stand for Investigating Multipulse Insulator Surface Flashover by Kallas, N. D., Andrews, H. L., Dale, G. E., Dalmas, D. A., Flores, P. A.

“…Insulator surface flashover in vacuum due to pulsed and DC voltages has been thoroughly investigated, however the characteristics of surface flashover under…”
Get full text

Relationships between Lewy bodies and pale bodies in Parkinson's disease by Dale, G E, Probst, A, Luthert, P, Martin, J, Anderton, B H, Leigh, P N

“…The prevalence of pale bodies and Lewy bodies was studied in the substantia nigra of 12 patients with typical Parkinson's disease (PD), in 5 patients with…”
Get full text

Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon by Oefner, C, D'Arcy, A, Hennig, M, Winkler, F K, Dale, G E

“…Neutral endopeptidase is a mammalian type II integral membrane zinc-containing endopeptidase, which degrades and inactivates a number of bioactive peptides…”
Get full text

Neurofibrillary tangles in dementia pugilistica are ubiquitinated by Dale, G E, Leigh, P N, Luthert, P, Anderton, B H, Roberts, G W

“…Ubiquitin, a protein thought to be involved in the ATP-dependent non-lysosomal degradation of abnormal proteins, has already been identified as a component of…”
Get full text

Characterization of the gene for chromosomal trimethoprim-sensitive dihydrofolate reductase of Staphylococcus aureus ATCC 25923 by Dale, G E, Then, R L, Stüber, D

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif by Kostrewa, Dirk, Brockhaus, Manfred, D'Arcy, Allan, Dale, Glenn E., Nelboeck, Peter, Schmid, Georg, Mueller, Francis, Bazzoni, Gianfranco, Dejana, Elisabetta, Bartfai, Tamas, Winkler, Fritz K., Hennig, Michael

“…Junctional adhesion molecules (JAMs) are a family of immunoglobulin‐like single‐span transmembrane molecules that are expressed in endothelial cells,…”
Get full text

Improving protein solubility through rationally designed amino acid replacements: solubilization of the trimethoprim-resistant type S1 dihydrofolate reductase by Dale, G E, Broger, C, Langen, H, D'Arcy, A, Stüber, D

“…In recent years resistance to the antibacterial agent trimethoprim (Tmp) has become more widespread and several Tmp-resistant (Tmpr) dihydrofolate reductases…”
Get more information

Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from staphylococcus aureus by Hennig, Michael, D′Arcy, Allan, Hampele, Isabella C, Page, Malcolm G.P, Oefner, Christian, Dale, Glenn E

“…Dihydroneopterin aldolase catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin during the de novo synthesis of folic acid from…”
Get full text

New aspects of the pathology of neurodegenerative disorders as revealed by ubiquitin antibodies by LEIGH, P. N, PROBST, A, DALE, G. E, POWER, D. P, BRION, J.-P, DODSON, A, ANDERTON, B. H

“…Ubiquitin has previously been identified as a component of neuronal inclusions in neurodegenerative disorders. In this investigation, we examined tissue from…”
Get full text

Spinal cord trauma in man: studies of phosphorylated neurofilament and ubiquitin expression by Martin, J E, Mather, K S, Swash, M, Garofalo, O, Dale, G E, Leigh, P N, Anderton, B H

“…Changes in neuronal proteins are a major feature of the neurodegenerative disorders, but the biological significance of these changes is not understood. We…”
Get more information

Prevalence of antibodies to herpes simplex virus types 1 and 2 in pregnant women, and estimated rates of infection by Ades, A E, Peckham, C S, Dale, G E, Best, J M, Jeansson, S

“…There has been a recent increase in notifications of genital herpes but it is not known whether this has been reflected in the pregnant population. We have…”
Get full text