Search Results - "Dale, Erica A."

Cervical afferents are necessary for closed‐loop epidural stimulation‐induced respiratory neuroplasticity by Mickle, Alyssa, Nosacka, Rachel L., Tobon, Julian, Dale, Erica A.

“…Epidural electrical stimulation restores vital functions in neurological disorders such as stroke and spinal cord injury. After spinal injury, epidural…”
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Intermittent hypoxia and neurorehabilitation by Gonzalez-Rothi, Elisa J, Lee, Kun-Ze, Dale, Erica A, Reier, Paul J, Mitchell, Gordon S, Fuller, David D

“…In recent years, it has become clear that brief, repeated presentations of hypoxia [i.e., acute intermittent hypoxia (AIH)] can boost the efficacy of more…”
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Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease by Vose, Alicia K., Welch, Joseph F., Nair, Jayakrishnan, Dale, Erica A., Fox, Emily J., Muir, Gillian D., Trumbower, Randy D., Mitchell, Gordon S.

“…We review progress towards greater mechanistic understanding and clinical translation of a strategy to improve respiratory and non-respiratory motor function…”
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Severe acute intermittent hypoxia elicits phrenic long-term facilitation by a novel adenosine-dependent mechanism by Nichols, Nicole L, Dale, Erica A, Mitchell, Gordon S

“…Acute intermittent hypoxia [AIH; 3, 5-min episodes; 35-45 mmHg arterial PO(2) (Pa(O(2)))] elicits serotonin-dependent phrenic long-term facilitation (pLTF), a…”
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Phrenic motor neuron TrkB expression is necessary for acute intermittent hypoxia-induced phrenic long-term facilitation by Dale, Erica A., Fields, Daryl P., Devinney, Michael J., Mitchell, Gordon S.

“…Phrenic long-term facilitation (pLTF) is a form of hypoxia-induced spinal respiratory motor plasticity that requires new synthesis of brain derived…”
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BDNF-induced phrenic motor facilitation shifts from PKCθ to ERK dependence with mild systemic inflammation by Agosto-Marlin, Ibis M, Nikodemova, Maria, Dale, Erica A, Mitchell, Gordon S

“…Moderate acute intermittent hypoxia (mAIH) elicits a form of phrenic motor plasticity known as phrenic long-term facilitation (pLTF), which requires spinal…”
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Spinal cord stimulation reduces ventricular arrhythmias during acute ischemia by attenuation of regional myocardial excitability by Howard-Quijano, Kimberly, Takamiya, Tatsuo, Dale, Erica A, Kipke, Jasmine, Kubo, Yukiko, Grogan, Tristan, Afyouni, Andyshea, Shivkumar, Kalyanam, Mahajan, Aman

“…Myocardial ischemia creates autonomic nervous system imbalance and can trigger cardiac arrhythmias. We hypothesized that neuromodulation by spinal cord…”
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Electrical epidural stimulation of the cervical spinal cord: implications for spinal respiratory neuroplasticity after spinal cord injury by Malone, Ian G, Nosacka, Rachel L, Nash, Marissa A, Otto, Kevin J, Dale, Erica A

“…Traumatic cervical spinal cord injury (cSCI) can lead to damage of bulbospinal pathways to the respiratory motor nuclei and consequent life-threatening…”
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Cervical spinal erythropoietin induces phrenic motor facilitation via extracellular signal-regulated protein kinase and Akt signaling by Dale, Erica A, Satriotomo, Irawan, Mitchell, Gordon S

“…Erythropoietin (EPO) is typically known for its role in erythropoiesis but is also a potent neurotrophic/neuroprotective factor for spinal motor neurons…”
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Spinal Anesthesia Reduces Myocardial Ischemia–triggered Ventricular Arrhythmias by Suppressing Spinal Cord Neuronal Network Interactions in Pigs by Omura, Yukiko, Kipke, Jasmine P., Salavatian, Siamak, Afyouni, Andrew Shea, Wooten, Christian, Herkenham, Robert F., Maoz, Uri, Lashgari, Elnaz, Dale, Erica A., Howard-Quijano, Kimberly, Mahajan, Aman

“…Cardiac sympathoexcitation leads to ventricular arrhythmias. Spinal anesthesia modulates sympathetic output and can be cardioprotective. However, its effect on…”
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Repetitive acute intermittent hypoxia increases expression of proteins associated with plasticity in the phrenic motor nucleus by Satriotomo, Irawan, Dale, Erica A., Dahlberg, Jenny M., Mitchell, Gordon S.

“…Acute intermittent hypoxia (AIH) initiates plasticity in respiratory motor control, including phrenic long term facilitation (pLTF). Since pLTF is enhanced by…”
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Effect of Thoracic Epidural Anesthesia on Ventricular Excitability in a Porcine Model by Howard-Quijano, Kimberly, Takamiya, Tatsuo, Dale, Erica A, Yamakawa, Kentaro, Zhou, Wei, Buckley, Una, Mahajan, Aman

“…BACKGROUND:Imbalances in the autonomic nervous system, namely, excessive sympathoexcitation, contribute to ventricular tachyarrhythmias. While thoracic…”
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Phrenic long-term facilitation requires PKCθ activity within phrenic motor neurons by Devinney, Michael J, Fields, Daryl P, Huxtable, Adrianne G, Peterson, Timothy J, Dale, Erica A, Mitchell, Gordon S

“…Acute intermittent hypoxia (AIH) induces a form of spinal motor plasticity known as phrenic long-term facilitation (pLTF); pLTF is a prolonged increase in…”
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Spinal cord neural network interactions: implications for sympathetic control of the porcine heart by Dale, Erica A, Kipke, Jasmine, Kubo, Yukiko, Sunshine, Michael D, Castro, Peter A, Ardell, Jeffrey L, Mahajan, Aman

“…Inherent and acquired factors determine the integrated autonomic response to cardiovascular stressors. Excessive sympathoexcitation to ischemic stress is a…”
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Closed-loop cervical epidural stimulation partially restores ipsilesional diaphragm EMG after acute C2 hemisection by Mickle, Alyssa R., Peñaloza-Aponte, Jesús D., Coffey, Richard, Hall, Natale A., Baekey, David, Dale, Erica A.

“…Cervical spinal cord injury creates lasting respiratory deficits which can require mechanical ventilation long-term. We have shown that closed-loop epidural…”
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Spinal plasticity following intermittent hypoxia: implications for spinal injury by Dale-Nagle, Erica A., Hoffman, Michael S., MacFarlane, Peter M., Satriotomo, Irawan, Lovett-Barr, Mary Rachael, Vinit, Stéphane, Mitchell, Gordon S.

“…Plasticity is a fundamental property of the neural system controlling breathing. One frequently studied model of respiratory plasticity is long‐term…”
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Progression of myocardial ischemia leads to unique changes in immediate-early gene expression in the spinal cord dorsal horn by Saddic, Louis A, Howard-Quijano, Kimberly, Kipke, Jasmine, Kubo, Yukiko, Dale, Erica A, Hoover, Donald, Shivkumar, Kalyanam, Eghbali, Mansoureh, Mahajan, Aman

“…The pathological consequences of ischemic heart disease involve signaling through the autonomic nervous system. Although early activation may serve to maintain…”
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Intermittent Hypoxia and Stem Cell Implants Preserve Breathing Capacity in a Rodent Model of Amyotrophic Lateral Sclerosis by NICHOLS, Nicole L, GOWING, Genevieve, MITCHELL, Gordon S, SATRIOTOMO, Irawan, NASHOLD, Lisa J, DALE, Erica A, SUZUKI, Masatoshi, AVALOS, Pablo, MULCRONE, Patrick L, MCHUGH, Jacalyn, SVENDSEN, Clive N

“…Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease causing paralysis and death from respiratory failure. Strategies to preserve and/or…”
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Formation of a novel supraspinal-spinal connectome that relearns the same motor task after complete paralysis by Urban, Luke Stuart, Thornton, Michael A, Ingraham Dixie, Katie L, Dale, Erica A, Zhong, Hui, Phelps, Patricia E, Burdick, Joel W, Edgerton, V Reggie

“…Having observed that electrical spinal cord stimulation and training enabled four patients with paraplegia with motor complete paralysis to regain voluntary…”
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The phrenic neuromuscular system by Fuller, David D, Rana, Sabhya, Smuder, Ashley J, Dale, Erica A

“…The phrenic neuromuscular system consists of the phrenic motor nucleus in the mid-cervical spinal cord, the phrenic nerve, and the diaphragm muscle. This motor…”
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