Search Results - "Dale, A."

A fully automated flow-based approach for accelerated peptide synthesis by Mijalis, Alexander J, Thomas, Dale A, Simon, Mark D, Adamo, Andrea, Beaumont, Ryan, Jensen, Klavs F, Pentelute, Bradley L

“…An automated method for solid-phase polypeptide synthesis capitalizes on rapid amide bond formation to enable the production of multiple traditionally…”
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The molecular basis and disease relevance of non-homologous DNA end joining by Zhao, Bailin, Rothenberg, Eli, Ramsden, Dale A., Lieber, Michael R.

“…Non-homologous DNA end joining (NHEJ) is the predominant repair mechanism of any type of DNA double-strand break (DSB) during most of the cell cycle and is…”
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A robotic platform for flow synthesis of organic compounds informed by AI planning by Coley, Connor W, Thomas, 3rd, Dale A, Lummiss, Justin A M, Jaworski, Jonathan N, Breen, Christopher P, Schultz, Victor, Hart, Travis, Fishman, Joshua S, Rogers, Luke, Gao, Hanyu, Hicklin, Robert W, Plehiers, Pieter P, Byington, Joshua, Piotti, John S, Green, William H, Hart, A John, Jamison, Timothy F, Jensen, Klavs F

“…The synthesis of complex organic molecules requires several stages, from ideation to execution, that require time and effort investment from expert chemists…”
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Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining by Ramsden, Dale A., Carvajal-Garcia, Juan, Gupta, Gaorav P.

“…Cellular pathways that repair chromosomal double-strand breaks (DSBs) have pivotal roles in cell growth, development and cancer. These DSB repair pathways have…”
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A RADIO-SELECTED SAMPLE OF GAMMA-RAY BURST AFTERGLOWS by CHANDRA, Poonam, FRAIL, Dale A

“…We present a catalog of radio afterglow observations of gamma-ray bursts (GRBs) over a 14 year period from 1997 to 2011. Our sample of 304 afterglows consists…”
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Effect of Sleep Extension on Objectively Assessed Energy Intake Among Adults With Overweight in Real-life Settings: A Randomized Clinical Trial by Tasali, Esra, Wroblewski, Kristen, Kahn, Eva, Kilkus, Jennifer, Schoeller, Dale A

“…Short sleep duration has been recognized as a risk factor for obesity. Whether extending sleep duration may mitigate this risk remains unknown. To determine…”
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An analytical chemist with on-the-job training in human nutrition by Schoeller, Dale A.

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Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines by Leivonen, S-K, Mäkelä, R, Östling, P, Kohonen, P, Haapa-Paananen, S, Kleivi, K, Enerly, E, Aakula, A, Hellström, K, Sahlberg, N, Kristensen, V N, Børresen-Dale, A-L, Saviranta, P, Perälä, M, Kallioniemi, O

“…Predicting the impact of microRNAs (miRNAs) on target proteins is challenging because of their different regulatory effects at the transcriptional and…”
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Traditional Self-Reported Dietary Instruments Are Prone to Inaccuracies and New Approaches Are Needed by Ravelli, Michele N, Schoeller, Dale A

“…Diet is a modifiable behavior that influences an individual's health. Because of this, diet assessment is an important component of public health surveillance,…”
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The effect of holiday weight gain on body weight by Schoeller, Dale A

“…Abstract The topic of holiday weight gain has been a frequent subject of the lay media, however, scientific interest has only been recent. Multiple studies in…”
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Mechanisms driving chromosomal translocations: lost in time and space by Ramsden, Dale A., Nussenzweig, Andre

“…Translocations arise when an end of one chromosome break is mistakenly joined to an end from a different chromosome break. Since translocations can lead to…”
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Graphene electrochemistry: an overview of potential applications by Brownson, Dale A C, Banks, Craig E

“…Graphene, a 2D nanomaterial that possesses spectacular physical, chemical and thermal properties, has caused immense excitement amongst scientists since its…”
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Constrained Total Energy Expenditure and Metabolic Adaptation to Physical Activity in Adult Humans by Pontzer, Herman, Durazo-Arvizu, Ramon, Dugas, Lara R., Plange-Rhule, Jacob, Bovet, Pascal, Forrester, Terrence E., Lambert, Estelle V., Cooper, Richard S., Schoeller, Dale A., Luke, Amy

“…Current obesity prevention strategies recommend increasing daily physical activity, assuming that increased activity will lead to corresponding increases in…”
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Quantitative Proteomics of the Cancer Cell Line Encyclopedia by Nusinow, David P., Szpyt, John, Ghandi, Mahmoud, Rose, Christopher M., McDonald, E. Robert, Kalocsay, Marian, Jané-Valbuena, Judit, Gelfand, Ellen, Schweppe, Devin K., Jedrychowski, Mark, Golji, Javad, Porter, Dale A., Rejtar, Tomas, Wang, Y. Karen, Kryukov, Gregory V., Stegmeier, Frank, Erickson, Brian K., Garraway, Levi A., Sellers, William R., Gygi, Steven P.

“…Proteins are essential agents of biological processes. To date, large-scale profiling of cell line collections including the Cancer Cell Line Encyclopedia…”
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Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19) by McCreary, Marvin R., Schnell, Patrick M., Rhoda, Dale A.

“…Resveratrol is a polyphenol that has been well studied and has demonstrated anti-viral and anti-inflammatory properties that might mitigate the effects of…”
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Comparison of self-reported dietary intakes from the Automated Self-Administered 24-h recall, 4-d food records, and food-frequency questionnaires against recovery biomarkers by Park, Yikyung, Dodd, Kevin W, Kipnis, Victor, Thompson, Frances E, Potischman, Nancy, Schoeller, Dale A, Baer, David J, Midthune, Douglas, Troiano, Richard P, Bowles, Heather, Subar, Amy F

“…ABSTRACT Background A limited number of studies have evaluated self-reported dietary intakes against objective recovery biomarkers. Objective The aim was to…”
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A widespread methylotroph acyl-homoserine lactone synthase produces a new quorum sensing signal that regulates swarming in Methylobacterium fujisawaense by Wallace, Mike, Cummings, Jr, Dale A, Roberts, Andrew G, Puri, Aaron W

“…Bacteria known as pink-pigmented facultative methylotrophs colonize many diverse environments on earth, play an important role in the carbon cycle, and in some…”
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Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks by Wyatt, David W., Feng, Wanjuan, Conlin, Michael P., Yousefzadeh, Matthew J., Roberts, Steven A., Mieczkowski, Piotr, Wood, Richard D., Gupta, Gaorav P., Ramsden, Dale A.

“…DNA polymerase theta (Pol θ)-mediated end joining (TMEJ) has been implicated in the repair of chromosome breaks, but its cellular mechanism and role relative…”
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Mechanistic basis for microhomology identification and genome scarring by polymerase theta by Carvajal-Garcia, Juan, Cho, Jang-Eun, Carvajal-Garcia, Pablo, Feng, Wanjuan, Wood, Richard D., Sekelsky, Jeff, Gupta, Gaorav P., Roberts, Steven A., Ramsden, Dale A.

“…DNA polymerase theta mediates an end joining pathway (TMEJ) that repairs chromosome breaks. It requires resection of broken ends to generate long, 3′…”
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The Evolution of Public Health Emergency Management as a Field of Practice by Rose, Dale A, Murthy, Shivani, Brooks, Jennifer, Bryant, Jeffrey

“…The health impacts of recent global infectious disease outbreaks and other disasters have demonstrated the importance of strengthening public health systems to…”
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