Search Results - "Dalal, Vijit"

Chemical chaperones assist intracellular folding to buffer mutational variations by Bandyopadhyay, Anannya, Saxena, Kanika, Kasturia, Neha, Dalal, Vijit, Bhatt, Niraj, Rajkumar, Asher, Maity, Shuvadeep, Sengupta, Shantanu, Chakraborty, Kausik

“…Osmolytes act as chemical chaperones capable of directly assisting the folding of destabilizing mutations in proteins in vivo , with different osmolytes having…”
Get full text

Confined Water in Amyloid-Competent Oligomers of the Prion Protein by Dalal, Vijit, Arya, Shruti, Mukhopadhyay, Samrat

“…Conformational switching of the prion protein into the abnormal form involves the formation of (obligatory) molten‐oligomers that mature into ordered amyloid…”
Get full text

Appearance of annular ring-like intermediates during amyloid fibril formation from human serum albumin by Arya, Shruti, Kumari, Arpana, Dalal, Vijit, Bhattacharya, Mily, Mukhopadhyay, Samrat

“…The self-assembly of proteins triggered by a conformational switch into highly ordered β-sheet rich amyloid fibrils has captivated burgeoning interest in…”
Get more information

Conformational Switching and Nanoscale Assembly of Human Prion Protein into Polymorphic Amyloids via Structurally Labile Oligomers by Dalal, Vijit, Arya, Shruti, Bhattacharya, Mily, Mukhopadhyay, Samrat

“…Conformational switching of the prion protein (PrP) from an α-helical normal cellular form (PrPC) to an aggregation-prone and self-propagating β-rich scrapie…”
Get full text

Direct Observation of the Intrinsic Backbone Torsional Mobility of Disordered Proteins by Jain, Neha, Narang, Dominic, Bhasne, Karishma, Dalal, Vijit, Arya, Shruti, Bhattacharya, Mily, Mukhopadhyay, Samrat

“…The fundamental backbone dynamics of unfolded proteins arising due to intrinsic ϕ-ψ dihedral angle fluctuations dictate the course of protein folding, binding,…”
Get full text

Classification of Chemical Chaperones Based on Their Effect on Protein Folding Landscapes by Dandage, Rohan, Bandyopadhyay, Anannya, Jayaraj, Gopal Gunanathan, Saxena, Kanika, Dalal, Vijit, Das, Aritri, Chakraborty, Kausik

“…Various small molecules present in biological systems can assist protein folding in vitro and are known as chemical chaperones. De novo design of chemical…”
Get full text

Nanoscale Fluorescence Imaging of Single Amyloid Fibrils by Dalal, Vijit, Bhattacharya, Mily, Narang, Dominic, Sharma, Pushpender K, Mukhopadhyay, Samrat

“…Amyloid formation is implicated in a variety of human diseases. It is important to perform high-resolution optical imaging of individual amyloid fibrils to…”
Get full text

Nanoscale Assembly of Proteins into Amyloid Oligomers, Pores and Fibrils by Bhattacharya, Mily, Jain, Neha, Dogra, Priyanka, Dalal, Vijit, Narang, Dominic, Sharma, Pushpender K., Samai, Soumyadyuti, Mukhopadhyay, Samrat

Get full text