Search Results - "Dal Bo, Michele"

New Insight into Therapies Targeting Angiogenesis in Hepatocellular Carcinoma by Mossenta, Monica, Busato, Davide, Baboci, Lorena, Cintio, Federica Di, Toffoli, Giuseppe, Bo, Michele Dal

“…Hepatocellular carcinoma (HCC) is a malignancy characterized by neoangiogenesis that is determined by an augmented production of proangiogenesis factors by…”
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Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia by Tissino, Erika, Benedetti, Dania, Herman, Sarah E M, Ten Hacken, Elisa, Ahn, Inhye E, Chaffee, Kari G, Rossi, Francesca Maria, Dal Bo, Michele, Bulian, Pietro, Bomben, Riccardo, Bayer, Elisabeth, Härzschel, Andrea, Gutjahr, Julia Christine, Postorino, Massimiliano, Santinelli, Enrico, Ayed, Ayed, Zaja, Francesco, Chiarenza, Annalisa, Pozzato, Gabriele, Chigaev, Alexandre, Sklar, Larry A, Burger, Jan A, Ferrajoli, Alessandra, Shanafelt, Tait D, Wiestner, Adrian, Del Poeta, Giovanni, Hartmann, Tanja Nicole, Gattei, Valter, Zucchetto, Antonella

“…The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib, which antagonizes B cell receptor (BCR) signals, demonstrates remarkable clinical activity in chronic…”
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The Dual Role of the Liver in Nanomedicine as an Actor in the Elimination of Nanostructures or a Therapeutic Target by Macor, Paolo, Toffoli, Giuseppe, Argenziano, Monica, Dal Bo, Michele, Mauro, Prisca, Colombo, Federico, Di Cintio, Federica, Capolla, Sara, Baboci, Lorena, Cavalli, Roberta

“…The development of nanostructures for therapeutic purpose is rapidly growing, following the results obtained in vivo in animal models and in the clinical…”
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HIF-1α is over-expressed in leukemic cells from TP53 -disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia by Griggio, Valentina, Vitale, Candida, Todaro, Maria, Riganti, Chiara, Kopecka, Joanna, Salvetti, Chiara, Bomben, Riccardo, Bo, Michele Dal, Magliulo, Daniela, Rossi, Davide, Pozzato, Gabriele, Bonello, Lisa, Marchetti, Monia, Omedè, Paola, Kodipad, Ahad Ahmed, Laurenti, Luca, Del Poeta, Giovanni, Mauro, Francesca Romana, Bernardi, Rosa, Zenz, Thorsten, Gattei, Valter, Gaidano, Gianluca, Foà, Robin, Massaia, Massimo, Boccadoro, Mario, Coscia, Marta

“…In chronic lymphocytic leukemia (CLL), the hypoxia-inducible factor 1 (HIF-1) regulates the response of tumor cells to hypoxia and their protective…”
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SF3B1 -mutated chronic lymphocytic leukemia shows evidence of NOTCH1 pathway activation including CD20 downregulation by Pozzo, Federico, Bittolo, Tamara, Tissino, Erika, Vit, Filippo, Vendramini, Elena, Laurenti, Luca, D'Arena, Giovanni, Olivieri, Jacopo, Pozzato, Gabriele, Zaja, Francesco, Chiarenza, Annalisa, Di Raimondo, Francesco, Zucchetto, Antonella, Bomben, Riccardo, Rossi, Francesca Maria, Del Poeta, Giovanni, Dal Bo, Michele, Gattei, Valter

“…Chronic lymphocytic leukemia (CLL) is characterized by a low CD20 expression, in part explained by an epigenetic-driven downregulation triggered by mutations…”
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Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia by Del Principe, Maria Ilaria, Dal Bo, Michele, Bittolo, Tamara, Buccisano, Francesco, Rossi, Francesca Maria, Zucchetto, Antonella, Rossi, Davide, Bomben, Riccardo, Maurillo, Luca, Cefalo, Mariagiovanna, De Santis, Giovanna, Venditti, Adriano, Gaidano, Gianluca, Amadori, Sergio, de Fabritiis, Paolo, Gattei, Valter, Del Poeta, Giovanni

“…In chronic lymphocytic leukemia the balance between the pro-apoptotic and anti-apoptotic members of the bcl-2 family is involved in the pathogenesis,…”
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A B-cell receptor-related gene signature predicts response to ibrutinib treatment in mantle cell lymphoma cell lines by D'Agaro, Tiziana, Zucchetto, Antonella, Vit, Filippo, Bittolo, Tamara, Tissino, Erika, Rossi, Francesca Maria, Degan, Massimo, Zaja, Francesco, Bulian, Pietro, Bo, Michele Dal, Ferrero, Simone, Ladetto, Marco, Zamò, Alberto, Gattei, Valter, Bomben, Riccardo

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Expression of the transcribed ultraconserved region 70 and the related long non‐coding RNA AC092652.2‐202 has prognostic value in Chronic Lymphocytic Leukaemia by Bomben, Riccardo, Roisman, Alejandro, D'Agaro, Tiziana, Castellano, Giancarlo, Baumann, Tycho, Delgado, Julio, López‐Guillermo, Armando, Zucchetto, Antonella, Dal‐Bo, Michele, Bravin, Vanessa, Slavutsky, Irma, Vlasova, Anna, Guigó, Roderic, Martin‐Subero, Jose I., Chapaprieta, Vicente, Beekman, Renee, Martin‐García, David, Beà, Sílvia, Salaverria, Itziar, Aymerich, Marta, Campo, Elias, Gattei, Valter, Hernández, Luis

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Microenvironmental Interactions in Chronic Lymphocytic Leukemia: The Master Role of CD49d by Dal Bo, Michele, Tissino, Erika, Benedetti, Dania, Caldana, Chiara, Bomben, Riccardo, Del Poeta, Giovanni, Gaidano, Gianluca, Rossi, Francesca Maria, Zucchetto, Antonella, Gattei, Valter

“…Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease characterized by the accumulation/expansion of a clonal population of neoplastic cells…”
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Mutational status of IGHV is the most reliable prognostic marker in trisomy 12 chronic lymphocytic leukemia by Bulian, Pietro, Bomben, Riccardo, Bo, Michele Dal, Zucchetto, Antonella, Rossi, Francesca Maria, Degan, Massimo, Pozzo, Federico, Bittolo, Tamara, Bravin, Vanessa, D'Agaro, Tiziana, Cerri, Michaela, Chiarenza, Annalisa, Chaffee, Kari G, Condoluci, Adalgisa, D'Arena, Giovanni, Spina, Michele, Zaja, Francesco, Pozzato, Gabriele, Di Raimondo, Francesco, Rossi, Davide, Poeta, Giovanni Del, Gaidano, Gianluca, Shanafelt, Tait D, Gattei, Valter

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A new approach for the treatment of CLL using chlorambucil/hydroxychloroquine-loaded anti-CD20 nanoparticles by Capolla, Sara, Mezzaroba, Nelly, Zorzet, Sonia, Tripodo, Claudio, Mendoza-Maldonado, Ramiro, Granzotto, Marilena, Vita, Francesca, Spretz, Ruben, Larsen, Gustavo, Noriega, Sandra, Mansilla, Eduardo, Dal Bo, Michele, Gattei, Valter, Pozzato, Gabriele, Núñez, Luis, Macor, Paolo

“…Current approaches for the treatment of chronic lymphocytic leukemia （CLL） have greatly improved the prognosis for survival, but some patients remain…”
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Glucose Metabolism and Oxidative Stress in Hepatocellular Carcinoma: Role and Possible Implications in Novel Therapeutic Strategies by Mossenta, Monica, Busato, Davide, Dal Bo, Michele, Toffoli, Giuseppe

“…Hepatocellular carcinoma (HCC) metabolism is redirected to glycolysis to enhance the production of metabolic compounds employed by cancer cells to produce…”
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Role of Virus-Related Chronic Inflammation and Mechanisms of Cancer Immune-Suppression in Pathogenesis and Progression of Hepatocellular Carcinoma by Borgia, Melissa, Dal Bo, Michele, Toffoli, Giuseppe

“…Hepatocellular carcinoma (HCC) can be classified as a prototypical inflammation-driven cancer that generally arises from a background of liver cirrhosis, but…”
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CD69 is independently prognostic in chronic lymphocytic leukemia: a comprehensive clinical and biological profiling study by DEL POETA, Giovanni, DEL PRINCIPE, Maria Ilaria, NERI, Benedetta, BOMBEN, Riccardo, SIMOTTI, Cristina, COLETTA, Angela Maria, DAL BO, Michele, DE FABRITIIS, Paolo, VENDITTI, Adriano, GATTEI, Valter, AMADORI, Sergio, ZUCCHETTO, Antonella, LUCIANO, Fabrizio, BUCCISANO, Francesco, ROSSI, Francesca Maria, BRUNO, Antonio, BIAGI, Annalisa, BULIAN, Pietro, MAURILLO, Luca

“…CD69 is expressed in several hemopoietic cells and is an early activation marker in chronic lymphocytic leukemia. Chronic lymphocytic leukemia is a clinically…”
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A comprehensive overview on antibody-drug conjugates: from the conceptualization to cancer therapy by Riccardi, Federico, Dal Bo, Michele, Macor, Paolo, Toffoli, Giuseppe

“…Antibody-Drug Conjugates (ADCs) represent an innovative class of potent anti-cancer compounds that are widely used in the treatment of hematologic malignancies…”
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Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia by Rossi, Davide, Rasi, Silvia, Spina, Valeria, Bruscaggin, Alessio, Monti, Sara, Ciardullo, Carmela, Deambrogi, Clara, Khiabanian, Hossein, Serra, Roberto, Bertoni, Francesco, Forconi, Francesco, Laurenti, Luca, Marasca, Roberto, Dal-Bo, Michele, Rossi, Francesca Maria, Bulian, Pietro, Nomdedeu, Josep, Del Poeta, Giovanni, Gattei, Valter, Pasqualucci, Laura, Rabadan, Raul, Foà, Robin, Dalla-Favera, Riccardo, Gaidano, Gianluca

“…The identification of new genetic lesions in chronic lymphocytic leukemia (CLL) prompts a comprehensive and dynamic prognostic algorithm including gene…”
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Pharmacological strategies to prevent SARS-CoV-2 infection and treat the early phases of COVID-19 by Scarabel, Lucia, Guardascione, Michela, Dal Bo, Michele, Toffoli, Giuseppe

“…[Display omitted] A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the cause of coronavirus disease 2019 (COVID-19). It…”
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Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges by Mondello, Alessia, Dal Bo, Michele, Toffoli, Giuseppe, Polano, Maurizio

“…Over the past two decades, Next-Generation Sequencing (NGS) has revolutionized the approach to cancer research. Applications of NGS include the identification…”
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Novel Nanotechnology Approaches to Overcome Drug Resistance in the Treatment of Hepatocellular Carcinoma: Glypican 3 as a Useful Target for Innovative Therapies by Mossenta, Monica, Busato, Davide, Dal Bo, Michele, Macor, Paolo, Toffoli, Giuseppe

“…Hepatocellular carcinoma (HCC) is the second most lethal tumor, with a 5-year survival rate of 18%. Early stage HCC is potentially treatable by therapies with…”
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Biological Features of Nanoparticles: Protein Corona Formation and Interaction with the Immune System by Panico, Sonia, Capolla, Sara, Bozzer, Sara, Toffoli, Giuseppe, Dal Bo, Michele, Macor, Paolo

“…Nanoparticles (NPs) are versatile candidates for nanomedical applications due to their unique physicochemical properties. However, their clinical applicability…”
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