A new experimental burn model with an infrared heater

This study was undertaken to develop new experimental burn injury model using conventional infrared heaters. 21 Sprague-Dawley rats were divided into 3 groups. Portion of dorsal area was exposed to infrared radiation from distance of 50 cm to create burn injury. Length of exposure to heat for Group...

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Bibliographic Details
Published in:	Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES Vol. 22; no. 5; pp. 412 - 416
Main Authors:	Güzey, Serbülent, Dal, Ahmet Demirhan, Şahin, İsmail, Nişancı, Mustafa, Yavan, İbrahim
Format:	Journal Article
Language:	English
Published:	Turkey 01-09-2016
Subjects:	Animals Burns - pathology Disease Models, Animal Infrared Rays Male Rats Rats, Sprague-Dawley Skin - injuries Skin - pathology
Online Access:	Get full text
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Summary:	This study was undertaken to develop new experimental burn injury model using conventional infrared heaters. 21 Sprague-Dawley rats were divided into 3 groups. Portion of dorsal area was exposed to infrared radiation from distance of 50 cm to create burn injury. Length of exposure to heat for Group 1 was 5 minutes; Group 2 was exposed for 7½ minutes, and Group 3 was exposed for 10 minutes. Macroscopic and histopathological evaluations were utilized to demonstrate depth and characteristics of injury. There was no burn injury in first group. Group 2 developed partial thickness burn, and result was full thickness burn injury in Group 3. In Groups 2 and 3 there was statistically significant difference in dermal collagen denaturation. Dermal injury depth was statistically significantly higher in Group 3 compared to Group 2. New experimental burn injury model is described using conventional infrared heaters. Standard variables pertaining to model were defined to produce burn injuries at predictable depth: 10 minutes of exposure from 50 cm distance for full thickness burn, and 7½ minutes of exposure from the same distance for partial thickness injury.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1306-696X
DOI:	10.5505/tjtes.2015.93464