Search Results - "Dakup, Panshak P"

Targeted Quantification of Protein Phosphorylation and Its Contributions towards Mathematical Modeling of Signaling Pathways by Dakup, Panshak P, Feng, Song, Shi, Tujin, Jacobs, Jon M, Wiley, H Steven, Qian, Wei-Jun

“…Post-translational modifications (PTMs) are key regulatory mechanisms that can control protein function. Of these, phosphorylation is the most common and…”
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The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study [version 2; peer review: 1 approved] by Koritala, Bala S. C., Dakup, Panshak P., Porter, Kenneth I., Gaddameedhi, Shobhan

“…Background: The natural day-night cycle synchronizes our circadian rhythms, but modern work practices like night shifts disrupt this pattern, leading to…”
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The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study [version 1; peer review: 1 approved, 1 approved with reservations] by Koritala, Bala S. C., Dakup, Panshak P., Porter, Kenneth I., Gaddameedhi, Shobhan

“…Background: The natural day-night cycle synchronizes our circadian rhythms, but modern work practices like night shifts disrupt this pattern, leading to…”
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The circadian clock protects against acute radiation-induced dermatitis by Dakup, Panshak P., Porter, Kenneth I., Gaddameedhi, Shobhan

“…Radiation-induced dermatitis is a common occurrence in cancer patients undergoing radiation therapy (RT) and is caused when ionizing radiation (IR) induces DNA…”
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Let’s talk about sex: A biological variable in immune response against melanoma by Dakup, Panshak P., Greer, Adam J., Gaddameedhi, Shobhan

“…As science culture gravitates toward a more holistic inclusion of both males and females in research design, the outlining of sex differences and their…”
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Telomere dysfunction in Tert knockout mice delays BrafV600E‐induced melanoma development by Zhang, Jinglong, Zhang, Fan, Porter, Kenneth I., Dakup, Panshak P., Wang, Shuwen, Robertson, Gavin P., Gaddameedhi, Shobhan, Zhu, Jiyue

“…Telomerase activation is a crucial step in melanomagenesis, often occurring because of ultraviolet radiation (UVR)‐induced mutations at the telomerase gene…”
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Telomere dysfunction in Tert knockout mice delays Braf V600E -induced melanoma development by Zhang, Jinglong, Zhang, Fan, Porter, Kenneth I, Dakup, Panshak P, Wang, Shuwen, Robertson, Gavin P, Gaddameedhi, Shobhan, Zhu, Jiyue

“…Telomerase activation is a crucial step in melanomagenesis, often occurring because of ultraviolet radiation (UVR)-induced mutations at the telomerase gene…”
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The circadian clock protects against ionizing radiation‐induced cardiotoxicity by Dakup, Panshak P., Porter, Kenneth I., Gajula, Rajendra P., Goel, Peeyush N., Cheng, Zhaokang, Gaddameedhi, Shobhan

“…ABSTRACT Radiation therapy (RT) is commonly used to treat solid tumors of the breast, lung, and esophagus; however, the heart is an unintentional target of…”
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Sex differences in the association between tumor growth and T cell response in a melanoma mouse model by Dakup, Panshak P., Porter, Kenneth I., Little, Alexander A., Zhang, Hui, Gaddameedhi, Shobhan

“…Epidemiological evidence suggests that females have an advantage over males in cases of melanoma incidence, progression, and survival. However, the biological…”
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Chemoprotective Effects of Dietary Grape Powder on UVB Radiation-Mediated Skin Carcinogenesis in SKH-1 Hairless Mice by Singh, Chandra K., Mintie, Charlotte A., Ndiaye, Mary A., Chhabra, Gagan, Dakup, Panshak P., Ye, Ting, Yu, Menggang, Ahmad, Nihal

“…Skin cancer is the most frequently diagnosed cancer in the United States, and solar UVR is an established causative factor for approximately 90% of these…”
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The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models by Dakup, Panshak P, Porter, Kenneth I, Little, Alexander A, Gajula, Rajendra P, Zhang, Hui, Skornyakov, Elena, Kemp, Michael G, Van Dongen, Hans P A, Gaddameedhi, Shobhan

“…Cisplatin is one of the most commonly used chemotherapeutic drugs; however, toxicity and tumor resistance limit its use. Studies using murine models and human…”
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Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells by Sarkar, Soumyadeep, Porter, Kenneth I., Dakup, Panshak P., Gajula, Rajendra P., Koritala, Bala S. C., Hylton, Ryan, Kemp, Michael G., Wakamatsu, Kazumasa, Gaddameedhi, Shobhan

“…Solar ultraviolet B radiation (UVB) is one of the leading causes of various skin conditions, including photoaging, sunburn erythema, and melanoma. As a…”
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Chronopharmacology of cisplatin: Role of the circadian rhythm in modulating the cisplatin transporters levels by Sorensen, Daniel N., Dakup, Panshak P., Gaddameedhi, Shobhan

“…Abstract only Purpose Cisplatin is one of the most commonly used chemotherapeutic drugs in treating a variety of tumors including cancers of ovaries, testis,…”
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It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes by Ashok Kumar, Prasanna V, Dakup, Panshak P, Sarkar, Soumyadeep, Modasia, Jinita B, Motzner, Madison S, Gaddameedhi, Shobhan

“…The circadian rhythm is established by a coordinated network of peripheral clocks interlocked and regulated by a central pacemaker. This network is maintained…”
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The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study [version 3; peer review: 2 approved] by Koritala, Bala S. C., Dakup, Panshak P., Porter, Kenneth I., Gaddameedhi, Shobhan

“…Background: The natural day-night cycle synchronizes our circadian rhythms, but modern work practices like night shifts disrupt this pattern, leading to…”
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Abstract 4159: Circadian clock protects against radiation-induced dermatitis and cardiomyopathy in mice by Dakup, Panshak P., Porter, Kenneth I., Cheng, Zhaokang, Gaddameedhi, Shobhan

“…Abstract Radiation therapy (RT) is commonly used in cancer treatment. Despite technological advances to improve precision external-beam RT in treating breast,…”
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Chemoprotective effects of dietary grape powder on ultraviolet B radiation-mediated skin carcinogenesis in SKH-1 hairless mice by Singh, Chandra K., Mintie, Charlotte A., Ndiaye, Mary A., Chhabra, Gagan, Dakup, Panshak P., Ye, Ting, Yu, Menggang, Ahmad, Nihal

“…Skin cancer is the most frequently diagnosed cancer in the US, and solar ultraviolet (UV) radiation is an established causative factor for ~90% of these cases…”
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Multi-Site Observational Study to Assess Biomarkers for Susceptibility or Resilience to Chronic Pain: The Acute to Chronic Pain Signatures (A2CPS) Study Protocol by Berardi, Giovanni, Frey-Law, Laura, Sluka, Kathleen A, Bayman, Emine O, Coffey, Christopher S, Ecklund, Dixie, Vance, Carol G T, Dailey, Dana L, Burns, John, Buvanendran, Asokumar, McCarthy, Robert J, Jacobs, Joshua, Zhou, Xiaohong Joe, Wixson, Richard, Balach, Tessa, Brummett, Chad M, Clauw, Daniel, Colquhoun, Douglas, Harte, Steven E, Harris, Richard E, Williams, David A, Chang, Andrew C, Waljee, Jennifer, Fisch, Kathleen M, Jepsen, Kristen, Laurent, Louise C, Olivier, Michael, Langefeld, Carl D, Howard, Timothy D, Fiehn, Oliver, Jacobs, Jon M, Dakup, Panshak, Qian, Wei-Jun, Swensen, Adam C, Lokshin, Anna, Lindquist, Martin, Caffo, Brian S, Crainiceanu, Ciprian, Zeger, Scott, Kahn, Ari, Wager, Tor, Taub, Margaret, Ford, James, Sutherland, Stephani P, Wandner, Laura D

“…Chronic pain has become a global health problem contributing to years lived with disability and reduced quality of life. Advances in the clinical management of…”
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