Search Results - "Dakik, Hassan"
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Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells
Published in Oncogene (06-02-2020)“…The bone marrow (BM) niche impacts the progression of acute myeloid leukemia (AML) by favoring the chemoresistance of AML cells. Intimate interactions between…”
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A comparative study of the capacity of mesenchymal stromal cell lines to form spheroids
Published in PloS one (02-06-2020)“…Mesenchymal stem cells (MSC)-spheroid models favor maintenance of stemness, ex vivo expansion and transplantation efficacy. Spheroids may also be considered as…”
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VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines
Published in International journal of molecular sciences (01-08-2020)“…Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) involvement has been established in the oncogenic cell signaling of acute myeloid leukemia…”
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Correction: Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells
Published in Oncogene (01-03-2020)“…The original version of this Article omitted the following from the Acknowledgements: This research was also supported by grants to KZ (UL and L-CNRS). This…”
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Analysis of the Neuroproteome Associated With Cell Therapy After Intranigral Grafting in a Mouse Model of Parkinson Disease
Published in Frontiers in neuroscience (11-03-2021)“…Advances in large-scale proteomics analysis have been very useful in understanding pathogenesis of diseases and elaborating therapeutic strategies. Proteomics…”
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The Diagnostic Yield of Repeated Endoscopic Evaluation in Patients with Gastrointestinal Bleeding and Left Ventricular Assist Devices
Published in Digestive diseases and sciences (01-06-2016)“…Introduction Left ventricular assist devices (LVADs) are increasingly common in patients with advanced heart failure. GI bleeding (GIB) occurs in 20–30 % of…”
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Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status
Published in Antioxidants (23-03-2021)“…In acute myeloid leukemia (AML), a low level of reactive oxygen species (ROS) is associated with leukemic stem cell (LSC) quiescence, whereas a high level…”
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Clinical Performance of Prediction Rules and Nasogastric Lavage for the Evaluation of Upper Gastrointestinal Bleeding: A Retrospective Observational Study
Published in Gastroenterology research and practice (01-01-2017)“…Introduction. The majority of patients with acute upper gastrointestinal bleeding (UGIB) are admitted for urgent endoscopy as it can be difficult to determine…”
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The use of GTX as second-line and later chemotherapy for metastatic pancreatic cancer: a retrospective analysis
Published in Cancer chemotherapy and pharmacology (01-02-2012)“…Purpose There are limited data regarding the role of second-line treatment for metastatic pancreatic cancer (mPC) after the failure of initial chemotherapy. No…”
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SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer
Published in Cell calcium (Edinburgh) (01-06-2021)“…[Display omitted] •SK4 protein expression is enhanced in colorectal cancer (CRC) tissues compared to normal colon tissues.•Level of KCNN4 Expression is higher…”
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The Role of Histone H3-K27M Mutation in Preleukemic HSC Expansion
Published in Blood (15-11-2022)Get full text
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Targeting Reactive Oxygen Species Metabolism to Induce Myeloma Cell Death
Published in Cancers (17-05-2021)“…Multiple myeloma (MM) is a common hematological disease characterized by the accumulation of clonal malignant plasma cells in the bone marrow. Over the past…”
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Management of Occluded Metal Stents in Malignant Biliary Obstruction: Similar Outcomes with Second Metal Stents Compared to Plastic Stents
Published in Digestive diseases and sciences (01-11-2012)“…Background Covered or uncovered self expandable metallic stents (SEMS) placed in patients with malignant biliary obstruction can occlude in 19–40 %, but…”
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Pannexin1 Is Associated with Enhanced Epithelial-To-Mesenchymal Transition in Human Patient Breast Cancer Tissues and in Breast Cancer Cell Lines
Published in Cancers (07-12-2019)“…Loss of connexin-mediated cell-cell communication is a hallmark of breast cancer progression. Pannexin1 (PANX1), a glycoprotein that shares structural and…”
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Expression Profiling of Calcium Channels and Calcium-Activated Potassium Channels in Colorectal Cancer
Published in Cancers (19-04-2019)“…: Colorectal cancer (CRC) is a highly devastating cancer. Ca -dependent channels are now considered key regulators of tumor progression. In this study, we…”
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Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells
Published in Journal of cellular and molecular medicine (01-09-2020)“…Acriflavine (ACF) is an antiseptic with anticancer properties, blocking the growth of solid and haematopoietic tumour cells. Moreover, this compound has been…”
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Diphenyleneiodonium Triggers Cell Death of Acute Myeloid Leukemia Cells by Blocking the Mitochondrial Respiratory Chain, and Synergizes with Cytarabine
Published in Cancers (18-05-2022)“…Acute myeloid leukemia (AML) is characterized by the accumulation of undifferentiated blast cells in the bone marrow and blood. In most cases of AML, relapse…”
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