Search Results - "Daiwile, Atul P"
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Neurotoxicity of methamphetamine: Main effects and mechanisms
Published in Experimental neurology (01-10-2021)“…Methamphetamine (METH) is an illicit psychostimulant that is abused throughout the world. METH addiction is also a major public health concern and the abuse of…”
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Sex-Specific Alterations in Dopamine Metabolism in the Brain after Methamphetamine Self-Administration
Published in International journal of molecular sciences (14-04-2022)“…Methamphetamine (METH) use disorder affects both sexes, with sex differences occurring in behavioral, structural, and biochemical consequences. The molecular…”
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Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts
Published in Neuroscience and biobehavioral reviews (01-06-2022)“…Methamphetamine (METH) use, and misuse are associated with severe socioeconomic consequences. METH users develop tolerance, lose control over drug taking…”
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Noncoding RNAs: Possible Players in the Development of Fluorosis
Published in BioMed research international (01-01-2015)“…Fluorosis is caused by excess of fluoride intake over a long period of time. Aberrant change in the Runt-related transcription factor 2 (RUNX2) mediated…”
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Modeling methamphetamine use disorder in mammals: Sex differences in behavioral, biochemical, and transcriptional consequences
Published in Advances in pharmacology (1990) (2024)“…Methamphetamine (METH) is the most commonly misused amphetamine-type stimulant throughout the globe. METH is very rewarding, and its misuse can lead to a…”
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Modeling methamphetamine use disorder and relapse in animals: Short- and long-term epigenetic, transcriptional., and biochemical consequences in the rat brain
Published in Neuroscience and biobehavioral reviews (01-12-2023)“…Methamphetamine use disorder (MUD) is a neuropsychiatric disorder characterized by binge drug taking episodes, intervals of abstinence, and relapses to drug…”
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Sex- and Brain Region-specific Changes in Gene Expression in Male and Female Rats as Consequences of Methamphetamine Self-administration and Abstinence
Published in Neuroscience (01-01-2021)“…•Both male and female rats escalated their METH intake.•Female had higher basal level expression of Hcrtr1 and Pdyn mRNAs in the PFC and HIP.•Male rats had…”
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Incubation of methamphetamine craving in punishment-resistant individuals is associated with activation of specific gene networks in the rat dorsal striatum
Published in Molecular psychiatry (01-07-2024)“…Methamphetamine use disorder (MUD) is characterized by loss of control over compulsive drug use. Here, we used a self-administration (SA) model to investigate…”
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Role of fluoride induced epigenetic alterations in the development of skeletal fluorosis
Published in Ecotoxicology and environmental safety (01-03-2019)“…Fluoride is an essential trace element required for proper bone and tooth development. Systemic high exposure to fluoride through environmental exposure…”
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Sex Differences in Escalated Methamphetamine Self-Administration and Altered Gene Expression Associated With Incubation of Methamphetamine Seeking
Published in The international journal of neuropsychopharmacology (01-11-2019)“…Methamphetamine (METH) use disorder is prevalent worldwide. There are reports of sex differences in quantities of drug used and relapses to drug use among…”
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Sex-Dependent Alterations in the mRNA Expression of Enzymes Involved in Dopamine Synthesis and Breakdown After Methamphetamine Self-Administration
Published in Neurotoxicity research (01-10-2022)“…Sex differences have been reported in methamphetamine (METH) use disorder in humans and in animal models of METH exposure. Specifically, animals that…”
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Manganese exposure: Linking down-regulation of miRNA-7 and miRNA-433 with α-synuclein overexpression and risk of idiopathic Parkinson's disease
Published in Toxicology in vitro (01-02-2018)“…Manganese is an essential trace element however elevated environmental and occupational exposure to this element has been correlated with neurotoxicity…”
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Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson’s disease-associated genes
Published in Archives of toxicology (01-07-2017)“…Manganese (Mn) is an essential trace element required for optimal functioning of cellular biochemical pathways in the central nervous system. Elevated exposure…”
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Chemogenetic Inhibition of Dopamine D1-expressing Neurons in the Dorsal Striatum does not alter Methamphetamine Intake in either Male or Female Long Evans Rats
Published in Neuroscience letters (11-06-2020)“…•METH intake is associated with increased expression of dopamine D1 receptors (D1R) in the dorsal striatum.•However, it is not clear that D1R in the dorsal…”
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Role of fluoride induced histone trimethylation in development of skeletal fluorosis
Published in Environmental toxicology and pharmacology (01-01-2018)“…[Display omitted] •Fluoride exposure resulted in increased level of H3K9 and H3K27 trimethylation & histone methyltransferases (EHMT1 and EHZ2).•Promoter…”
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Correlation of melanophore index with a battery of functional genomic stress indicators for measurement of environmental stress in aquatic ecosystem
Published in Environmental toxicology and pharmacology (01-03-2015)“…Graphical abstract…”
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Manganese exposure: Linking down-regulation of miRNA-7 and miRNA-433 with a-synuclein overexpression and risk of idiopathic Parkinson's disease
Published in Toxicology in vitro (01-02-2018)“…Manganese is an essential trace element however elevated environmental and occupational exposure to this element has been correlated with neurotoxicity…”
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