Search Results - "Daisuke Sawadaa"

Synthesis and Biological Activity of 1α,2α,25-Trihydroxyvitamin D3：Active Metabolite of 2α-(3-Hydroxypropoxy)-1α,25-dihydroxyvitamin D3 by Human CYP3A4 by Masashi Takanoa, Saori Ohyaa, Kaori Yasudab, Miyu Nishikawab, Akiko Takeuchic, Daisuke Sawadaa, Toshiyuki Sakakib, Atsushi Kittakaa

“…Our previous studies revealed that recombinant human CYP3A4 converted 2α-(3-hydroxypropoxy)-1α,25-dihydroxyvitamin D3 (O2C3), which was a more potent binder to…”
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Synthesis and Biological Activities of 1α,4α,25- and 1α,4β,25-Trihydroxyvitamin D3 and Their Metabolism by Human CYP24A1 and UDP-Glucuronosyltransferase by Daisuke Sawadaa, Yuya Tsukudaa, Kaori Yasudab, Toshiyuki Sakakib, Hiroshi Saitoc, Ken-ichiro Takagic, Kazuya Takenouchic, Tai C.Chend, G.Satyanarayana Reddye, f, Atsushi Kittakaa

“…A previous report has demonstrated the existence of a C4-hydroxylated vitamin D2 metabolite in serum of rats treated with pharmacological doses of vitamin D2…”
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Revisiting the 7,8-cis-vitamin D sub(3) derivatives: synthesis, evaluating the biological activity, and study of the binding configuration by Sawadaa, Daisuke, Kakudab, Shinji, Kamimura-Takimotob, Midori, Takeuchib, Akiko, Matsumotoa, Yotaro, Kittakaa, Atsushi

“…Four 7,8-cis-1 alpha ,25-dihydroxyvitamin D sub(3) derivatives, 7,8-cis- and 7,8-cis-14-epi-1 alpha ,25-dihydroxy-19-norvitamin D sub(3) as well as 7,8-cis-…”
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Synthesis and Biological Evaluation of 4-Substituted Vitamin D and 14-Epi-Previtamin D Analogs by Sawada, Daisuke, Tsukuda, Yuya, Saito, Hiroshi, Takagi, Ken-ichiro, Horie, Kyouhei, Ochiai, Eiji, Takenouchi, Kazuya, Kittaka, Atsushi

“…We synthesized the 4-hydroxy and 4-methoxy analogs of active vitamin D3 (1α,25(OH)2D3, 1) and its C14-epimer with the previtamin D3 form of…”
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