Single Probiotic versus Multiple Probiotics - A Debate On Current Scenario for Alleviating Health Benefits

Strain, dose, duration, validated clinical trial studies and scientific substantiation of health claims are needed in order to define a successful probiotic. In particular, the potency of probiotic differs from strain to strain. In this view, we aimed to know whether the single strain or multi-strai...

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Bibliographic Details
Published in:	Current pharmaceutical design Vol. 24; no. 35; p. 4150
Main Authors:	Korada, Siva K, Yarla, Nagendra S, Mishra, Vijayendra, Daim, Mohamed A, Sharma, Bechan, Gm, Ashraf, R, Reggi, M, Palmery, Peluso, Ilaria, Kamal, Mohammad A
Format:	Journal Article
Language:	English
Published:	United Arab Emirates 01-01-2018
Subjects:	Colitis - drug therapy Humans Inflammatory Bowel Diseases - drug therapy Probiotics - therapeutic use Probiotics single strain multiple probiotics health benefits safety recommendation gut microbiota
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Summary:	Strain, dose, duration, validated clinical trial studies and scientific substantiation of health claims are needed in order to define a successful probiotic. In particular, the potency of probiotic differs from strain to strain. In this view, we aimed to know whether the single strain or multi-strain construct is more beneficial. We found that the studies were still under debate and mechanisms remain sometimes unclear. No conclusion can be made based on the strain experimentation. Safety data and significant statistical results for efficacy via well-controlled clinical trials are needed.
ISSN:	1873-4286
DOI:	10.2174/1381612824666181012124136