Search Results - "Dailey, Michael E"

Microglia: Key Elements in Neural Development, Plasticity, and Pathology by Eyo, Ukpong B., Dailey, Michael E.

“…A century after Cajal identified a “third element” of the nervous system, many issues have been clarified about the identity and function of one of its major…”
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Fibronectin Splicing Variants Containing Extra Domain A Promote Atherosclerosis in Mice Through Toll-Like Receptor 4 by Doddapattar, Prakash, Gandhi, Chintan, Prakash, Prem, Dhanesha, Nirav, Grumbach, Isabella M, Dailey, Michael E, Lentz, Steven R, Chauhan, Anil K

“…OBJECTIVE—Cellular fibronectin containing extra domain A (EDA-FN) is abundant in the arteries of patients with atherosclerosis. Several in vitro studies…”
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Effects of oxygen-glucose deprivation on microglial mobility and viability in developing mouse hippocampal tissues by Eyo, Ukpong, Dailey, Michael E.

“…As brain‐resident immune cells, microglia (MG) survey the brain parenchyma to maintain homeostasis during development and following injury. Research in…”
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Developmental changes in microglial mobilization are independent of apoptosis in the neonatal mouse hippocampus by Eyo, Ukpong B, Miner, Samuel A, Weiner, Joshua A, Dailey, Michael E

“…Highlights • Microglia are surveilling cells involved in clearance of apoptotic cells. • In mouse hippocampus, the density of apoptotic bodies peaks around…”
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Neuronal activity regulates glutamate transporter dynamics in developing astrocytes by Benediktsson, Adrienne M., Marrs, Glen S., Tu, Jian Cheng, Worley, Paul F., Rothstein, Jeffrey D., Bergles, Dwight E., Dailey, Michael E.

“…Glutamate transporters (GluTs) maintain a low ambient level of glutamate in the central nervous system (CNS) and shape the activation of glutamate receptors at…”
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Dynamics of microglial activation: A confocal time-lapse analysis in hippocampal slices by Stence, Nick, Waite, Marc, Dailey, Michael E.

“…The dynamics of microglial cell activation was studied in freshly prepared rat brain tissue slices. Microglia became activated in the tissue slices, as…”
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Purines induce directed migration and rapid homing of microglia to injured pyramidal neurons in developing hippocampus by Kurpius, Dana, Nolley, Eric P., Dailey, Michael E.

“…Traumatic CNS injury activates and mobilizes resident parenchymal microglia (MG), which rapidly accumulate near injured neurons where they transform into…”
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Diverse microglial motility behaviors during clearance of dead cells in hippocampal slices by Petersen, Mark A., Dailey, Michael E.

“…We used two‐channel three‐dimensional time‐lapse fluorescence confocal imaging in live rat hippocampal slice cultures (1–7 days in vitro) to determine the…”
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Imaging microglia in brain slices and slice cultures by Dailey, Michael E, Eyo, Ukpong, Fuller, Leah, Hass, John, Kurpius, Dana

“…Here we describe a method for imaging fluorescently labeled parenchymal microglia (MG) in excised neonatal or adult rodent brain tissue slices. Using…”
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A Kinase Anchor Protein 150 (AKAP150)-associated Protein Kinase A Limits Dendritic Spine Density by Lu, Yuan, Zha, Xiang-ming, Kim, Eun Young, Schachtele, Scott, Dailey, Michael E., Hall, Duane D., Strack, Stefan, Green, Steven H., Hoffman, Dax A., Hell, Johannes W.

“…The A kinase anchor protein AKAP150 recruits the cAMP-dependent protein kinase (PKA) to dendritic spines. Here we show that in AKAP150 (AKAP5) knock-out (KO)…”
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The Dynamics of Dendritic Structure in Developing Hippocampal Slices by Dailey, Michael E, Smith, Stephen J

“…Time-lapse fluorescence confocal microscopy was used to directly visualize the formation and dynamics of postsynaptic target structures (i.e., dendritic…”
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Role of Ca2+/calmodulin-dependent protein kinase II in dendritic spine remodeling during epileptiform activity in vitro by Zha, Xiang-ming, Dailey, Michael E., Green, Steven H.

“…Epileptiform activity (EA) in vivo and in vitro induces a loss of dendritic spines and synapses. Because CaMKII has been implicated in synaptogenesis and…”
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The P2Y12 receptor regulates microglial activation by extracellular nucleotides by Haynes, Sharon E, Hollopeter, Gunther, Yang, Guang, Kurpius, Dana, Dailey, Michael E, Gan, Wen-Biao, Julius, David

“…Microglia are primary immune sentinels of the CNS. Following injury, these cells migrate or extend processes toward sites of tissue damage. CNS injury is…”
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Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood by Khan, Kanza M., Bierlein-De La Rosa, Gabrielle, Biggerstaff, Natalie, Pushpavathi Selvakumar, Govindhasamy, Wang, Ruixiang, Mason, Suzanne, Dailey, Michael E., Marcinkiewcz, Catherine A.

“…•Adolescent alcohol increased pain sensitivity and social deficits in adult male mice.•Adolescent alcohol induced microglial activation and reduced…”
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Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration by Ahlers, Katelin E., Karaçay, Bahri, Fuller, Leah, Bonthius, Daniel J., Dailey, Michael E.

“…Fetal alcohol exposure is the most common known cause of preventable mental retardation, yet we know little about how microglia respond to, or are affected by,…”
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Regulation of hippocampal synapse remodeling by epileptiform activity by Zha, Xiang-ming, Green, Steven H., Dailey, Michael E.

“…We examined the regulation of dendritic spines and synapses by epileptiform activity (EA) in rat hippocampal slice cultures. EA, which was induced by a GABA A…”
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Juxtavascular microglia migrate along brain microvessels following activation during early postnatal development by Grossmann, Ruth, Stence, Nick, Carr, Jenny, Fuller, Leah, Waite, Marc, Dailey, Michael E.

“…Some parenchymal microglia in mammalian brain tissues, termed “juxtavascular microglia,” directly contact the basal lamina of blood vessels; however, the…”
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Effects of 28-day nose-only inhalation of PCB52 (2,2′,5,5′-Tetrachlorobiphenyl) on the brain transcriptome by Bullert, Amanda J., Wang, Hui, Linahon, Morgan J., Chimenti, Michael S., Adamcakova-Dodd, Andrea, Li, Xueshu, Dailey, Michael E., Klingelhutz, Aloysius J., Ankrum, James A., Stevens, Hanna E., Thorne, Peter S., Lehmler, Hans-Joachim

“…A semi-volatile polychlorinated biphenyl (PCB) congener, PCB52, is present in the indoor air of schools; however, the effects of inhaled PCB52 on the brain…”
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Bispectral EEG (BSEEG) quantifying neuro-inflammation in mice induced by systemic inflammation: A potential mouse model of delirium by Yamanashi, Takehiko, Malicoat, Johnny R., Steffen, Kalvon T., Zarei, Kasra, Li, Rui, Purnell, Benton S., Najafi, Annice, Saito, Kenji, Singh, Uday, Toth, Brandon A., Lee, Shelley, Dailey, Michael E., Cui, Huxing, Kaneko, Koichi, Cho, Hyunkeun Ryan, Iwata, Masaaki, Buchanan, Gordon F., Shinozaki, Gen

“…Most of the animal studies using inflammation-induced cognitive change have relied on behavioral testing without objective and biologically solid methods to…”
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P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation by Eyo, Ukpong B., Miner, Sam A., Ahlers, Katelin E., Wu, Long-Jun, Dailey, Michael E.

“…Brain-resident microglia may promote tissue repair following stroke but, like other cells, they are vulnerable to ischemia. Here we identify mechanisms…”
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