Search Results - "Dailey, Gabrielle P"

Vaccines targeting ESR1 activating mutations elicit anti-tumor immune responses and suppress estrogen signaling in therapy resistant ER+ breast cancer by Dailey, Gabrielle P, Rabiola, Christopher A, Lei, Gangjun, Wei, Junping, Yang, Xiao-Yi, Wang, Tao, Liu, Cong-Xiao, Gajda, Melissa, Hobeika, Amy C, Summers, Amanda, Marek, Robert D, Morse, Michael A, Lyerly, Herbert K, Crosby, Erika J, Hartman, Zachary C

“…ER+ breast cancers (BC) are characterized by the elevated expression and signaling of estrogen receptor alpha ( , which renders them sensitive to…”
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Inhibition of selenoprotein synthesis by Zika virus may contribute to congenital Zika syndrome and microcephaly by mimicking SELENOP knockout and the genetic disease PCCA by Dailey, Gabrielle P., Premadasa, Lakmini S., Ruzicka, Jan A., Taylor, Ethan Will

“…•Loss of selenoprotein synthesis in the genetic disease PCCA leads to microcephaly.•We show potential antisense interactions between Zika RNA and selenoprotein…”
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Cancer vaccine strategies using self-replicating RNA viral platforms by Dailey, Gabrielle P., Crosby, Erika J., Hartman, Zachary C.

“…The development and success of RNA-based vaccines targeting SARS-CoV-2 has awakened new interest in utilizing RNA vaccines against cancer, particularly in the…”
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Direct Detection of Conserved Viral Sequences and Other Nucleic Acid Motifs with Solid-State Nanopores by Sethi, Komal, Dailey, Gabrielle P, Zahid, Osama K, Taylor, Ethan W, Ruzicka, Jan A, Hall, Adam R

“…The rapid and reliable recognition of nucleic acid sequences is essential to a broad range of fields including genotyping, gene expression analysis, and…”
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876 Self-replicating RNA therapeutics for off-the-shelf precision immunotherapy targeting acquired resistance mutations in low TMB tumors by Goldberg, Zelanna, Maine, Christian, Dailey, Gabrielle P, Domingo, Christine, Picarda, Gaelle, Little, Hunter, Chou, Annie, Sparks, Jessica, Spasova, Darina, Miyake-Stoner, Shigeki, Rabiola, Christopher A, Crosby, Erika J, Hartman, Zachary C, Lyerly, Herbert K, Wang, Nathaniel, Aliahmad, Parinaz

“…BackgroundKeynote-942 (AACR 2023; ASCO 2023) represents the first clinical success of a personalized cancer vaccine. mRNA-4157 is a personalized neoantigen…”
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Abstract 6403: A self-replicating RNA precision medicine approach to overcoming resistance to endocrine therapy in ER+BC by Goldberg, Zelanna, Maine, Christian, Dailey, Gabrielle P., Domingo, Christine, Picarda, Gaelle, Little, Hunter, Chou, Annie, Sparks, Jessica, Spasova, Darina, Miyake-Stoner, Shigeki, Hartman, Zachary C., Rabiola, Christopher A., Crosby, Erika J., Lyerly, Herbert K., Wang, Nathaniel, Aliahmad, Parinaz

“…Abstract Drug resistance remains the major driving factor behind the clinical failure of targeted therapeutics. Current oncology precision medicine approaches…”
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Abstract 2732: A self-replicating RNA precision medicine approach to therapeutic protein delivery of narrow therapeutic index biomolecules by Goldberg, Zelanna, Maine, Christian, Dailey, Gabrielle P., Domingo, Christine, Picarda, Gaelle, Little, Hunter, Chou, Annie, Sparks, Jessica, Spasova, Darina, Miyake-Stoner, Shigeki, Rabiola, Christopher A., Crosby, Erika J., Hartman, Zachary C., Lyerly, Herbert K., Wang, Nathaniel, Aliahmad, Parinaz

“…Abstract Protein drug replacement using nucleic acid technologies has been a sought-after solution for in situ production of proteins with poor half-lives and…”
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