Search Results - "Dai, K. R."

Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone by Dai, K R, Xu, X L, Tang, T T, Zhu, Z A, Yu, C F, Lou, J R, Zhang, X L

“…Bone defects larger than a critical size are major challenges in orthopedic medicine. We combined tissue-engineered bone and gene therapy to provide…”
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OA10 Is a Novel p38alpha Mitogen-Activated Protein Kinase Inhibitor That Suppresses Osteoclast Differentiation and Bone Resorption by Jiang, T., Qin, A., Shao, Z.Y., Tian, B., Zhai, Z.J., Li, H.W., Zhu, Z.A., Dai, K.R., Ming, H. Zheng, Yu, Y.P., Jiang, Q.

“…ABSTRACT In search of anti‐bone resorbing agents for the potential treatment of osteoporosis, we synthesized a novel compound Tert‐butyl…”
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Andrographolide suppresses RANKL‐induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo by Zhai, Z J, Li, H W, Liu, G W, Qu, X H, Tian, B, Yan, W, Lin, Z, Tang, T T, Qin, A, Dai, K R

“…Background and Purpose Osteoclasts play a pivotal role in diseases such as osteoporosis, rheumatoid arthritis and tumour bone metastasis. Thus, searching for…”
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V-ATPases in osteoclasts: Structure, function and potential inhibitors of bone resorption by Qin, A., Cheng, T.S., Pavlos, N.J., Lin, Z., Dai, K.R., Zheng, M.H.

“…► Summarizes recent research developments in V-ATPase biology. ► Highlights the structure, function and regulation of V-ATPases in osteoclasts. ► Discusses the…”
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BMP2 gene therapy on the repair of bone defects of aged rats by Yue, B, Lu, B, Dai, K R, Zhang, X L, Yu, C F, Lou, J R, Tang, T T

“…Age-related decline in the number of mesenchymal stem cells (MSCs) and their reduced capability to differentiate osteogenically, along with diminished…”
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Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats by TANG, T. T, LU, B, YUE, B, XIE, X. H, XIE, Y. Z, DAI, K. R, LU, J. X, LOU, J. R

“…The efficacy of beta-tricalcium phosphate (beta-TCP) loaded with bone morphogenetic protein-2 (BMP-2)-gene-modified bone-marrow mesenchymal stem cells (BMSCs)…”
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BMP2Gene Therapy on the Repair of Bone Defects of Aged Rats by Yue, B., Lu, B., Dai, K. R., Zhang, X. L., Yu, C. F., Lou, J. R., Tang, T. T.

“…Age-related decline in the number of mesenchymal stem cells (MSCs) and their reduced capability to differentiate osteogenically, along with diminished…”
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OA-4 inhibits osteoclast formation and bone resorption via suppressing RANKL induced P38 signaling pathway by Tian, B, Qin, A, Shao, Z Y, Jiang, T, Zhai, Z J, Li, H W, Tang, T T, Jiang, Q, Dai, K R, Zheng, M H, Yu, Y P, Zhu, Z A

“…Osteoclasts are one of the key therapeutic targets for a variety of orthopedic diseases such as osteoporosis and osteoarthritis. In this study, we synthesized…”
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Biologic effect and immunoisolating behavior of BMP-2 gene-transfected bone marrow-derived mesenchymal stem cells in APA microcapsules by Ding, H.F., Liu, R., Li, B.G., Lou, J.R., Dai, K.R., Tang, T.T.

“…We investigated the encapsulation of BMP-2 gene-modified mesenchymal stem cells (MSCs) in alginate-poly- l-lysine (APA) microcapsules for the persistent…”
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Treatment of intra-articular fractures with shape memory compression staples by Dai, K R, Hou, X K, Sun, Y H, Tang, R G, Qiu, S J, Ni, C

“…The management of intra-articular fractures remains difficult. Shape memory compression staples fulfil nearly all the special treatment requirements of…”
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Short Baseline TerraSAR-X PSI for Monitoring Subsidence of Highways and Railways, Case Study with Corner Reflectors by Yu, B., Liu, G. X., Jia, H. G., Dai, K. R., Zhang, R., Li, T., Wang, X. W., Ma, D. Y.

“…Ground subsidence is one of the key factors causing damages to transportation facilities, e.g., transportation network (TN) consists of highways and railways…”
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Reverse engineering in CAD model reconstruction of customized artificial joint by Lin, Yan-Ping, Wang, Cheng-Tao, Dai, Ke-Rong

“…In order to meet the requirements of customized artificial joint design, and to reduce the production cycle and cost, we present a method to generate the…”
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Cleft sternum and ecopia cordis - case report and brief review by Chang, T.-S., Qian, Y.-L., Tang, S.-C., Dai, K.-R., Sun, B.-S., Jin, R.

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Bone remodelling after internal fixation with different stiffness plates: ultrastructural investigation by Chen, Y Q, Dai, K R, Qiu, S J, Zhu, Z A

“…Forty adult New Zealand rabbits were used in this experiment. Four rabbits served as control and the rest 36 being divided into 3 groups, each of which was…”
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The arch structure of trabeculae in normal femoral head and its biomechanical significance by Qiu, S J, Dai, K R

“…The microstructure of the normal human femoral head was observed under light and electron microscope. Most of the trabeculae were seen in the form of arch…”
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Repair of regional osteoporosis after removal of rigid fixing plate. An experimental investigation by Zhu, Z A, Dai, K R, Qiu, S J

“…Twenty-four New Zealand white rabbits were plated on their intact left tibiae with stainless steel plates and 4 animals served as controls. The plates were…”
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Proliferation and osteoblastic differentiation of human bone marrow stromal cells on hydroxyapatite/bacterial cellulose nanocomposite scaffolds by Fang, Bo, Wan, Yi-Zao, Tang, Ting-Tang, Gao, Chuan, Dai, Ke-Rong

“…In this study, we prepared hydroxyapatite/bacterial cellulose (HAp/BC) nanocomposite scaffolds utilizing the biomimetic technique, and investigated the…”
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Mesoporous bioactive glass as a drug delivery system: fabrication, bactericidal properties and biocompatibility by Li, Yang, Liu, Yi-Zhuo, Long, Teng, Yu, Xi-Bin, Tang, Ting–Ting, Dai, Ke-Rong, Tian, Bo, Guo, Ya-Ping, Zhu, Zhen-An

“…Implant-associated infection remains a difficult medical problem in orthopaedic surgery. Here, we report on the fabrication of gentamicin-loaded mesoporous…”
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Effect of internal fixation plates on microcirculation in under-plate cortical bones. Microangiography and scanning electronmicroscopy by Wang, Y, Dai, K R

“…To elucidate the effect of the internal fixation plates on the local bone blood supply, we used microangiography and scanning electron microscopy to observe…”
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Promotion of osteogenesis through β-catenin signaling by desferrioxamine by Qu, Zhi-Hu, Zhang, Xiao-Ling, Tang, Ting-Ting, Dai, Ke-Rong

“…Desferrioxamine, an iron chelator with “hypoxia-mimetic” activity, promotes bone mineralization when used in aluminum-overloaded dialysis patients. However,…”
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