Search Results - "Dahunsi, Debolanle O."

Low-Salt Diet Reduces Anti-CTLA4 Mediated Systemic Immune-Related Adverse Events while Retaining Therapeutic Efficacy against Breast Cancer by Khandekar, Durga, Dahunsi, Debolanle O, Manzanera Esteve, Isaac V, Reid, Sonya, Rathmell, Jeffrey C, Titze, Jens, Tiriveedhi, Venkataswarup

“…Immune checkpoint inhibitor (ICI) therapy has revolutionized the breast cancer treatment landscape. However, ICI-induced systemic inflammatory immune-related…”
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Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response by Levine, Lauren S., Hiam-Galvez, Kamir J., Marquez, Diana M., Tenvooren, Iliana, Madden, Matthew Z., Contreras, Diana C., Dahunsi, Debolanle O., Irish, Jonathan M., Oluwole, Olalekan O., Rathmell, Jeffrey C., Spitzer, Matthew H.

“…Memory T cells are thought to rely on oxidative phosphorylation and short-lived effector T cells on glycolysis. Here, we investigated how T cells arrive at…”
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Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation by Healey, Diana C Contreras, Cephus, Jacqueline Y, Barone, Sierra M, Chowdhury, Nowrin U, Dahunsi, Debolanle O, Madden, Matthew Z, Ye, Xiang, Yu, Xuemei, Olszewski, Kellen, Young, Kirsten, Gerriets, Valerie A, Siska, Peter J, Dworski, Ryszard, Hemler, Jonathan, Locasale, Jason W, Poyurovsky, Masha V, Peebles, Jr, R Stokes, Irish, Jonathan M, Newcomb, Dawn C, Rathmell, Jeffrey C

“…T effector cells promote inflammation in asthmatic patients, and both Th2 and Th17 CD4 T cells have been implicated in severe forms of the disease. The…”
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Systems Immunology Analyses of STAT1 Gain-of-Function Immune Phenotypes Reveal Heterogeneous Response to IL-6 and Broad Immunometabolic Roles for STAT1 by Kaviany, Saara, Bartkowiak, Todd, Dulek, Daniel E, Khan, Yasmin W, Hayes, Madeline J, Schaefer, Samuel G, Ye, Xiang, Dahunsi, Debolanle O, Connelly, James A, Irish, Jonathan M, Rathmell, Jeffrey C

“…Patients with gain-of-function (GOF) pathogenic variants have enhanced or prolonged STAT1 phosphorylation following cytokine stimulation and exhibit increased…”
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Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk by Greenwood, Dalton L, Ramsey, Haley E, Nguyen, Phuong T T, Patterson, Andrew R, Voss, Kelsey, Bader, Jackie E, Sugiura, Ayaka, Bacigalupa, Zachary A, Schaefer, Samuel, Ye, Xiang, Dahunsi, Debolanle O, Madden, Matthew Z, Wellen, Kathryn E, Savona, Michael R, Ferrell, P Brent, Rathmell, Jeffrey C

“…Hematopoiesis integrates cytokine signaling, metabolism, and epigenetic modifications to regulate blood cell generation. These processes are linked, as…”
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Metabolic characteristics of Th2 and Th17 cells drive airway inflammation by Contreras, Diana C, Cephus, Jacqueline Y, Dahunsi, Debolanle O, Newcomb, Dawn C, Rathmell, Jeffrey C

“…Asthma is an airway inflammatory disease that is mediated by T effector (Teff) cells, specifically Th2 and Th17 cells. Increases in disease severity leading to…”
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