Search Results - "Dahlmans, Vivian E.H"

Contribution of Fatty Acids Released From Lipolysis of Plasma Triglycerides to Total Plasma Fatty Acid Flux and Tissue-Specific Fatty Acid Uptake by TEUSINK, Bas, VOSHOL, Peter J, DAHLMANS, Vivian E. H, RENSEN, Patrick C. N, PIJL, Hanno, RAMIJN, Johannes A, HAVEKES, Louis M

“…Contribution of Fatty Acids Released From Lipolysis of Plasma Triglycerides to Total Plasma Fatty Acid Flux and Tissue-Specific Fatty Acid Uptake Bas Teusink 1…”
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In Muscle-Specific Lipoprotein Lipase−Overexpressing Mice, Muscle Triglyceride Content Is Increased Without Inhibition of Insulin-Stimulated Whole-Body and Muscle-Specific Glucose Uptake by VOSHOL, Peter J, JONG, Miek C, DAHLMANS, Vivian E. H, KRATKY, Dagmar, LEVAK-FRANK, Sanja, ZECHNER, Rudolf, ROMIJN, Johannes A, HAVEKES, Louis M

“…In Muscle-Specific Lipoprotein Lipase−Overexpressing Mice, Muscle Triglyceride Content Is Increased Without Inhibition of Insulin-Stimulated Whole-Body and…”
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Protection From Obesity in Mice Lacking the VLDL Receptor by Goudriaan, Jeltje R, Tacken, Paul J, Dahlmans, Vivian E.H, Gijbels, Marion J.J, van Dijk, Ko Willems, Havekes, Louis M, Jong, Miek C

“…It has previously been reported that mice lacking the VLDL receptor (VLDLR−/−) exhibit normal plasma lipid levels and a modest decrease in adipose tissue mass…”
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Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification by Westerterp, Marit, Berbée, Jimmy F.P., Delsing, Dianne J.M., Jong, Miek C., Gijbels, Marion J.J., Dahlmans, Vivian E.H., Offerman, Erik H., Romijn, Johannes A., Havekes, Louis M., Rensen, Patrick C.N.

“…Mice that overexpress human apolipoprotein C-I (apoC-I) homozygously (APOC1+/+ mice) are protected against obesity and show cutaneous abnormalities. Although…”
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Defective Intercellular Adhesion Complex in Myocardium Predisposes to Infarct Rupture in Humans by van den Borne, Susanne W.M., MD, Narula, Jagat, MD, PhD, FACC, Voncken, J. Willem, PhD, Lijnen, Peter M., BSc, Vervoort-Peters, Helena T.M., BSc, Dahlmans, Vivian E.H., BSc, Smits, Jos F.M., PhD, Daemen, Mat J.A.P., MD, PhD, Blankesteijn, W. Matthijs, PhD

“…Defective Intercellular Adhesion Complex in Myocardium Predisposes to Infarct Rupture in Humans Susanne W. M. van den Borne, Jagat Narula, J. Willem Voncken,…”
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Protection From Obesity and Insulin Resistance in Mice Overexpressing Human Apolipoprotein C1 by JONG, Miek C, VOSHOL, Peter J, MUURLING, Martin, DAHLMANS, Vivian E. H, ROMIJN, Johannes A, PIJL, Hanno, HAVEKES, Louis M

“…Protection From Obesity and Insulin Resistance in Mice Overexpressing Human Apolipoprotein C1 Miek C. Jong 1 , Peter J. Voshol 1 2 , Martin Muurling 1 , Vivian…”
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CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice by Goudriaan, Jeltje R., Dahlmans, Vivian E.H., Teusink, Bas, Ouwens, D. Margriet, Febbraio, Maria, Maassen, J. Anton, Romijn, Johannes A., Havekes, Louis M., Voshol, Peter J.

“…CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and…”
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Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice by Jong, M C, Rensen, P C, Dahlmans, V E, van der Boom, H, van Berkel, T J, Havekes, L M

“…Previous studies with hypertriglyceridemic APOC3 transgenic mice have suggested that apolipoprotein C-III (apoC-III) may inhibit either the apoE-mediated…”
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Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice by van Ree, J H, van den Broek, W J, Dahlmans, V E, Groot, P H, Vidgeon-Hart, M, Frants, R R, Wieringa, B, Havekes, L M, Hofker, M H

“…Apolipoprotein (apo) E is a ligand for the receptor-mediated uptake of lipoprotein remnant particles. Complete absence of apo E in humans leads to a severe…”
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Both Lipolysis and Hepatic Uptake of VLDL Are Impaired in Transgenic Mice Coexpressing Human Apolipoprotein E3Leiden and Human Apolipoprotein C1 by Jong, Miek C, Dahlmans, Vivian E.H, van Gorp, Patrick J.J, Breuer, Marco L, Mol, Marc J.T.M, van der Zee, Andre, Frants, Rune R, Hofker, Marten H, Havekes, Louis M

“…Transgenic mice overexpressing human APOE*3Leiden are highly susceptible to diet-induced hyperlipoproteinemia and atherosclerosis due to a defect in hepatic…”
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The immediate early gene product EGR1 and polycomb group proteins interact in epigenetic programming during chondrogenesis by Spaapen, Frank, van den Akker, Guus G H, Caron, Marjolein M J, Prickaerts, Peggy, Rofel, Celine, Dahlmans, Vivian E H, Surtel, Don A M, Paulis, Yvette, Schweizer, Finja, Welting, Tim J M, Eijssen, Lars M, Voncken, Jan Willem

“…Initiation of and progression through chondrogenesis is driven by changes in the cellular microenvironment. At the onset of chondrogenesis, resting mesenchymal…”
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Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia by Adriaens, Michiel E, Prickaerts, Peggy, Chan-Seng-Yue, Michelle, van den Beucken, Twan, Dahlmans, Vivian E H, Eijssen, Lars M, Beck, Timothy, Wouters, Bradly G, Voncken, Jan Willem, Evelo, Chris T A

“…A comprehensive assessment of the epigenetic dynamics in cancer cells is the key to understanding the molecular mechanisms underlying cancer and to improving…”
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Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3 by Prickaerts, Peggy, Adriaens, Michiel E, Beucken, Twan van den, Koch, Elizabeth, Dubois, Ludwig, Dahlmans, Vivian E H, Gits, Caroline, Evelo, Chris T A, Chan-Seng-Yue, Michelle, Wouters, Bradly G, Voncken, Jan Willem

“…Trimethylation at histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) controls gene activity during development and differentiation. Whether H3K4me3 and…”
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MK3 modulation affects BMI1-dependent and independent cell cycle check-points by Prickaerts, Peggy, Niessen, Hanneke E C, Dahlmans, Vivian E H, Spaapen, Frank, Salvaing, Juliette, Vanhove, Jolien, Geijselaers, Claudia, Bartels, Stefanie J J, Partouns, Iris, Neumann, Dietbert, Speel, Ernst-Jan, Takihara, Yoshihiro, Wouters, Bradly G, Voncken, Jan Willem

“…Although the MK3 gene was originally found deleted in some cancers, it is highly expressed in others. The relevance of MK3 for oncogenesis is currently not…”
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PRC1 Prevents Replication Stress during Chondrogenic Transit Amplification by Spaapen, Frank, Eijssen, Lars, Adriaens, Michiel, Welting, Tim, Prickaerts, Peggy, Salvaing, Juliette, Dahlmans, Vivian, Surtel, Donald, Kruitz, Frans, Kuijer, Roel, Takihara, Yoshihiro, Marks, Hendrik, Stunnenberg, Hendrik, Wouters, Bradly, Vidal, Miguel, Voncken, Jan

“…Transit amplification (TA), a state of combined, rapid proliferative expansion and differentiation of stem cell-descendants, remains poorly defined at the…”
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Intestinal lipid absorption is not affected in CD36 deficient mice by Goudriaan, Jeltje R, Dahlmans, Vivian E H, Febbraio, Maria, Teusink, Bas, Romijn, Johannes A, Havekes, Louis M, Voshol, Peter J

“…Increasing evidence has implicated the membrane protein CD36 (or fatty acid translocase, FAT) to be involved in high affinity fatty acid uptake. CD36 is…”
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Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1 by Jong, M C, Gijbels, M J, Dahlmans, V E, Gorp, P J, Koopman, S J, Ponec, M, Hofker, M H, Havekes, L M

“…Transgenic mice were generated with different levels of human apolipoprotein C1 (APOC1) expression in liver and skin. At 2 mo of age, serum levels of…”
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MK3 controls Polycomb target gene expression via negative feedback on ERK by Prickaerts, Peggy, Niessen, Hanneke Ec, Mouchel-Vielh, Emmanuèle, Dahlmans, Vivian Eh, van den Akker, Guus Gh, Geijselaers, Claudia, Adriaens, Michiel E, Spaapen, Frank, Takihara, Yoshihiro, Rapp, Ulf R, Peronnet, Frédérique, Voncken, Jan Willem

“…Gene-environment interactions are mediated by epigenetic mechanisms. Polycomb Group proteins constitute part of an epigenetic cellular transcriptional memory…”
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A low-fat diet has a higher potential than energy restriction to improve high-fat diet-induced insulin resistance in mice by Muurling, Martin, Jong, Miek C., Mensink, Ronald P., Hornstra, Gerard, Dahlmans, Vivian E.H., Pijl, Hanno, Voshol, Peter J., Havekes, Louis M.

“…Previous studies have shown that energy restriction (ER) or low-fat (LF) diets have beneficial effects on high-fat (HF) diet-induced obesity and non[ndash…”
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In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway by Jong, M C, Dahlmans, V E, van Gorp, P J, van Dijk, K W, Breuer, M L, Hofker, M H, Havekes, L M

“…To study the role of apoC1 in lipoprotein metabolism, we have generated transgenic mice expressing the human APOC1 gene. On a sucrose-rich diet, male…”
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