Search Results - "Dahlin, Anna M"

The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer by Edin, Sofia, Wikberg, Maria L, Dahlin, Anna M, Rutegård, Jörgen, Öberg, Åke, Oldenborg, Per-Arne, Palmqvist, Richard

“…High macrophage infiltration has been correlated to improved survival in colorectal cancer (CRC). Tumor associated macrophages (TAMs) play complex roles in…”
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Low-grade glioma risk SNP rs11706832 is associated with type I interferon response pathway genes in cell lines by Rosenbaum, Adam, Dahlin, Anna M., Andersson, Ulrika, Björkblom, Benny, Wu, Wendy Yi-Ying, Hedman, Håkan, Wibom, Carl, Melin, Beatrice

“…Genome-wide association studies (GWAS) have contributed to our understanding of glioma susceptibility. To date, 25 risk loci for development of any of the…”
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The Role of the CpG Island Methylator Phenotype in Colorectal Cancer Prognosis Depends on Microsatellite Instability Screening Status by DAHLIN, Anna M, PALMQVIST, Richard, HENRIKSSON, Maria L, JACOBSSON, Maria, EKLÖF, Vincy, RUTEGARD, Jörgen, ÖBERG, Ake, VAN GUELPEN, Bethany R

“…The aim of this study was to relate the CpG island methylator phenotype (CIMP; characterized by extensive promoter hypermethylation) to cancer-specific…”
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Travel time to care does not affect survival for patients with colorectal cancer in northern Sweden: A data linkage study from the Risk North database by Sjöström, Olle, Dahlin, Anna M, Silander, Gustav, Syk, Ingvar, Melin, Beatrice, Hellquist, Barbro Numan, Lee, Jung Eun

“…Introduction Numerous prior studies, even from countries with free access to care, have associated long travel time to care with poor survival in patients with…”
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Colorectal Cancer Cells Activate Adjacent Fibroblasts Resulting in FGF1/FGFR3 Signaling and Increased Invasion by Henriksson, Maria L, Edin, Sofia, Dahlin, Anna M, Oldenborg, Per-Arne, Öberg, Åke, Van Guelpen, Bethany, Rutegård, Jörgen, Stenling, Roger, Palmqvist, Richard

“…Cancer-associated fibroblasts expressing fibroblast activation protein (FAP) have been implicated in the invasive behavior of colorectal cancer. In this study,…”
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A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences by Svensson, Daniel, Rentoft, Matilda, Dahlin, Anna M, Lundholm, Emma, Olason, Pall I, Sjödin, Andreas, Nylander, Carin, Melin, Beatrice S, Trygg, Johan, Johansson, Erik

“…The number of national reference populations that are whole-genome sequenced are rapidly increasing. Partly driving this development is the fact that genetic…”
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Relation between Established Glioma Risk Variants and DNA Methylation in the Tumor by Dahlin, Anna M, Wibom, Carl, Ghasimi, Soma, Brännström, Thomas, Andersson, Ulrika, Melin, Beatrice

“…Genome-wide association studies and candidate gene studies have identified several genetic variants that increase glioma risk. The majority of these variants…”
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Pre‐diagnostic levels of sVEGFR2, sTNFR2, sIL‐2Rα and sIL‐6R are associated with glioma risk: A nested case–control study of repeated samples by Wu, Wendy Yi‐Ying, Späth, Florentin, Wibom, Carl, Björkblom, Benny, Dahlin, Anna M., Melin, Beatrice

“…No strong aetiological factors have been established for glioma aside from genetic mutations and variants, ionising radiation and an inverse relationship with…”
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High tumour cannabinoid CB1 receptor immunoreactivity negatively impacts disease-specific survival in stage II microsatellite stable colorectal cancer by Gustafsson, Sofia B, Palmqvist, Richard, Henriksson, Maria L, Dahlin, Anna M, Edin, Sofia, Jacobsson, Stig O P, Öberg, Åke, Fowler, Christopher J

“…There is good evidence in the literature that the cannabinoid system is disturbed in colorectal cancer. In the present study, we have investigated whether…”
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One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study by Van Guelpen, Bethany, Dahlin, Anna M, Hultdin, Johan, Eklöf, Vincy, Johansson, Ingegerd, Henriksson, Maria L, Cullman, Inger, Hallmans, Göran, Palmqvist, Richard

“…Objective We related prediagnostic plasma folate, vitamin B12, and total homocysteine concentrations, and the MTHFR 677C>T and 1298A>C polymorphisms, to the…”
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Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor by Dahlin, Anna M, Henriksson, Maria L, Van Guelpen, Bethany, Stenling, Roger, Öberg, Åke, Rutegård, Jörgen, Palmqvist, Richard

“…The aim of this study was to relate the density of tumor infiltrating T cells to cancer-specific survival in colorectal cancer, taking into consideration the…”
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High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis by Wikberg, Maria L., Edin, Sofia, Lundberg, Ida V., Van Guelpen, Bethany, Dahlin, Anna M., Rutegård, Jörgen, Stenling, Roger, Öberg, Åke, Palmqvist, Richard

“…-An active stroma is important for cancer cell invasion and metastasis. We investigated the expression of fibroblast activation protein (FAP) in relation to…”
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Multi-ancestry genome-wide association study of 4069 children with glioma identifies 9p21.3 risk locus by Foss-Skiftesvik, Jon, Li, Shaobo, Rosenbaum, Adam, Hagen, Christian Munch, Stoltze, Ulrik Kristoffer, Ljungqvist, Sally, Hjalmars, Ulf, Schmiegelow, Kjeld, Morimoto, Libby, de Smith, Adam J, Mathiasen, René, Metayer, Catherine, Hougaard, David, Melin, Beatrice, Walsh, Kyle M, Bybjerg-Grauholm, Jonas, Dahlin, Anna M, Wiemels, Joseph L

“…Abstract Background Although recent sequencing studies have revealed that 10% of childhood gliomas are caused by rare germline mutations, the role of common…”
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The association between longer relative leukocyte telomere length and risk of glioma is independent of the potentially confounding factors allergy, BMI, and smoking by Andersson, Ulrika, Degerman, Sofie, Dahlin, Anna M., Wibom, Carl, Johansson, Gunnar, Bondy, Melissa L., Melin, Beatrice S.

“…Purpose Previous studies have suggested an association between relative leukocyte telomere length (rLTL) and glioma risk. This association may be influenced by…”
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Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma by Ghasimi, Soma, Wibom, Carl, Dahlin, Anna M., Brännström, Thomas, Golovleva, Irina, Andersson, Ulrika, Melin, Beatrice

“…During the last years, genome wide association studies have discovered common germline genetic variants associated with specific glioma subtypes. We aimed to…”
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Investigation of established genetic risk variants for glioma in prediagnostic samples from a population-based nested case-control study by Wibom, Carl, Späth, Florentin, Dahlin, Anna M, Langseth, Hilde, Hovig, Eivind, Rajaraman, Preetha, Johannesen, Tom Børge, Andersson, Ulrika, Melin, Beatrice

“…Although glioma etiology is poorly understood in general, growing evidence indicates a genetic component. Four large genome-wide association studies (GWAS)…”
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Genetic Variants in the 9p21.3 Locus Associated with Glioma Risk in Children, Adolescents, and Young Adults: A Case-Control Study by Dahlin, Anna M, Wibom, Carl, Andersson, Ulrika, Hougaard, David M, Bybjerg-Grauholm, Jonas, Deltour, Isabelle, Hultman, Christina M, Kähler, Anna K, Karlsson, Robert, Hjalmars, Ulf, Melin, Beatrice

“…Genome-wide association studies have identified germline genetic variants in 25 genetic loci that increase the risk of developing glioma in adulthood. It is…”
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CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma by Dahlin, Anna M., Hollegaard, Mads V., Wibom, Carl, Andersson, Ulrika, Hougaard, David M., Deltour, Isabelle, Hjalmars, Ulf, Melin, Beatrice

“…Recent studies have described a number of genes that are frequently altered in medulloblastoma tumors and that have putative key roles in the development of…”
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Prediagnostic biomarkers for early detection of glioma—using case–control studies from cohorts as study approach by Wu, Wendy Yi-Ying, Dahlin, Anna M, Wibom, Carl, Björkblom, Benny, Melin, Beatrice

“…Abstract Background Understanding the trajectory and development of disease is important and the knowledge can be used to find novel targets for therapy and…”
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High SMAD4 levels appear in microsatellite instability and hypermethylated colon cancers, and indicate a better prognosis by Isaksson-Mettävainio, Martin, Palmqvist, Richard, Dahlin, Anna M., Van Guelpen, Bethany, Rutegård, Jörgen, Öberg, Åke, Henriksson, Maria L.

“…Colorectal cancer (CRC) is one of the most common causes of cancer‐related deaths in western countries. CRC are commonly divided in cancers showing…”
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