Search Results - "Dahlet, Thomas"
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Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
Published in Nature communications (19-06-2020)“…Mouse embryos acquire global DNA methylation of their genome during implantation. However the exact roles of DNA methyltransferases (DNMTs) in embryos have not…”
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E2F6 initiates stable epigenetic silencing of germline genes during embryonic development
Published in Nature communications (11-06-2021)“…In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes; however, the molecular mechanisms of this…”
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Studying DNA Methylation Genome-Wide by Bisulfite Sequencing from Low Amounts of DNA in Mammals
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…DNA methylation is extensively reprogrammed during mammalian embryogenesis and germ cell development. Protocols for genome-wide bisulfite sequencing enable the…”
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ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats
Published in Human molecular genetics (20-11-2024)“…Since its discovery as a causative gene of the Immunodeficiency with Centromeric instability and Facial anomalies syndrome, ZBTB24 has emerged as a key player…”
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