Search Results - "Dahan, Sophie"

Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction by Bergeron, John J.M, Di Guglielmo, Gianni M, Dahan, Sophie, Dominguez, Michel, Posner, Barry I

“…Epidermal growth factor (EGF) and insulin receptor tyrosine kinases (RTKs) exemplify how receptor location is coupled to signal transduction. Extracellular…”
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LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease by Brodeur, Julie, Thériault, Caroline, Lessard-Beaudoin, Mélissa, Marcil, Alexandre, Dahan, Sophie, Lavoie, Christine

“…The Aβ peptide that accumulates in Alzheimer's disease (AD) is derived from amyloid precursor protein (APP) following proteolysis by β- and γ-secretases…”
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Oxidation-induced Misfolding and Aggregation of Superoxide Dismutase and Its Implications for Amyotrophic Lateral Sclerosis by Rakhit, Rishi, Cunningham, Patricia, Furtos-Matei, Alexandra, Dahan, Sophie, Qi, Xiao-Fei, Crow, John P., Cashman, Neil R., Kondejewski, Leslie H., Chakrabartty, Avijit

“…The presence of intracellular aggregates that contain Cu/Zn superoxide dismutase (SOD1) in spinal cord motor neurons is a pathological hallmark of amyotrophic…”
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Current Screens Based on the AlphaScreen™ Technology for Deciphering Cell Signalling Pathways by Taouji, Saïd, Dahan, Sophie, Bossé, Roger, Chevet, Eric

“…Global deciphering of signal transduction pathways represents a new challenge of the post-genomic era. However, for the majority of these signaling pathways…”
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Single-Well Monitoring of Protein−Protein Interaction and Phosphorylation−Dephosphorylation Events by Arcand, Mathieu, Roby, Philippe, Bossé, Roger, Lipari, Francesco, Padrós, Jaime, Beaudet, Lucille, Marcil, Alexandre, Dahan, Sophie

“…We combined oxygen channeling assays with two distinct chemiluminescent beads to detect simultaneously protein phosphorylation and interaction events that are…”
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gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer by Dominguez, Michel, Dejgaard, Kurt, Füllekrug, Joachim, Dahan, Sophie, Fazel, Ali, Paccaud, Jean-Pierre, Thomas, David Y., John J. M. Bergeron, Nilsson, Tommy

“…Five mammalian members of the gp25L/emp24/p24 family have been identified as major constituents of the cis-Golgi network of rat liver and HeLa cells. Two of…”
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Development of a high-throughput AlphaScreen assay measuring full-length LRRK2(G2019S) kinase activity using moesin protein substrate by Pedro, Liliana, Padrós, Jaime, Beaudet, Lucille, Schubert, Hans-Dieter, Gillardon, Frank, Dahan, Sophie

“…Mutations within the LRRK2 (leucine-rich repeat kinase 2) gene predispose humans to develop late-onset Parkinson’s disease (PD). The most prevalent of these…”
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Secreted APP and amyloid beta quantification in SH‐SY5Y cell media using high sensitivity AlphaLISA kits by Hohenauer, Krystyna, Anani, Shihadeh, Marcil, Alexandre, Roby, Philippe, Parent, Stephane, Dahan, Sophie

“…The aggregation and accumulation of amyloid beta peptides is one of the pathological hallmarks of Alzheimer's disease (AD). Amyloid beta is produced by…”
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LDLR-related protein 10 trafficking and processing: evidence for a role in Alzheimer's disease by Brodeur, Julie, Thñriault, Caroline, Lessard-Beaudoin, Mñlissa, Marcil, Alexandre, Dahan, Sophie, Lavoie, Christine

“…Background The A[beta] peptide that accumulates in Alzheimer's disease (AD) is derived from amyloid precursor protein (APP) following proteolysis by [beta]-…”
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GBF1: A Novel Golgi-Associated BFA-Resistant Guanine Nucleotide Exchange Factor That Displays Specificity for ADP-Ribosylation Factor 5 by Claude, Alejandro, Zhao, Bao-Ping, Kuziemsky, Craig E., Dahan, Sophie, Berger, Scott J., Yan, Jian-Ping, Armold, Adrian D., Sullivan, Eric M., Melançon, Paul

“…Expression cloning from a cDNA library prepared from a mutant CHO cell line with Golgi-specific resistance to Brefeldin A (BFA) identified a novel 206-kD…”
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A Novel Dynamin-Like Protein Associates with Cytoplasmic Vesicles and Tubules of the Endoplasmic Reticulum in Mammalian Cells by Yoon, Yisang, Pitts, Kelly R., Dahan, Sophie, McNiven, Mark A.

“…Dynamins are 100-kilodalton guanosine triphosphatases that participate in the formation of nascent vesicles during endocytosis. Here, we have tested if novel…”
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Agonist-Induced Vesiculation of the Golgi Apparatus in Pancreatic Acinar Cells by Dahan, Sophie, Anderson, Karen L., Weller, Shaun, Krueger, Eugene, McNiven, Mark A.

“…Background & Aims: The pancreatic acinar cell is known to regulate exocytosis, total protein synthesis, and secretory protein transport in response to a…”
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Antibody-based Proteomics: From bench to bedside by Dahan, Sophie, Chevet, Eric, Liu, Jian-Feng, Dominguez, Michel

“…Over the past 75 years, antibodies have gone from being recognized as disease biomarkers to being used as very powerful therapeutic tools. This evolution has…”
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Fusogenic Domains of Golgi Membranes Are Sequestered into Specialized Regions of the Stack That Can Be Released by Mechanical Fragmentation by Dominguez, Michel, Fazel, Ali, Dahan, Sophie, Lovell, Jacque, Hermo, Louis, Claude, Alejandro, Melançon, Paul, Bergeron, J. J. M.

“…A well-characterized cell-free assay that reconstitutes Golgi transport is shown to require physically fragmented Golgi fractions for maximal activity. A Golgi…”
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Identification and characterization of an intracellular protein complex that binds fibroblast growth factor-2 in bovine brain by CHEVET, Eric, LEMAÎTRE, Gilles, CAILLERET, Karine, DAHAN, Sophie, BERGERON, John J. M., KATINKA, Michaël D.

“…The fibroblast growth factor (FGF) family is composed of polypeptides with sequence identity which signal through transmembrane tyrosine kinase receptors. We…”
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Identification and characterization of an intracellular protein complex that binds fibroblast growth factor-2 in bovine brain by Chevet, E, Lemaître, G, Cailleret, K, Dahan, S, Bergeron, J J, Katinka, M D

“…The fibroblast growth factor (FGF) family is composed of polypeptides with sequence identity which signal through transmembrane tyrosine kinase receptors. We…”
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Intracellular protein/membrane trafficking: Evaluation of the golgi and endosomal apparatus by cryoimmune electron microscopy by Dahan, Sophie

“…Protein trafficking events in the secretory and endosomal apparatus were evaluated in rat liver hepatocytes by EM immunogold cytochemistry. The cellular…”
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Gbf1 by Claude, Alejandro, Zhao, Bao-Ping, Kuziemsky, Craig E., Dahan, Sophie, Berger, Scott J., Yan, Jian-Ping, Armold, Adrian D., Sullivan, Eric M., Melançon, Paul

“…Expression cloning from a cDNA library prepared from a mutant CHO cell line with Golgi-specific resistance to Brefeldin A (BFA) identified a novel 206-kD…”
Get full text