Search Results - "Dahal, Bhola K"

Inhibition of MicroRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension by PULLAMSETTI, Soni S, DOEBELE, Carmen, SEEGER, Werner, ZEIHER, Andreas M, DIMMELER, Stefanie, SCHERMULY, Ralph T, FISCHER, Ariane, SAVAI, Rajkumar, KOJONAZAROV, Baktybek, DAHAL, Bhola K, GHOFRANI, Hossein A, WEISSMANN, Norbert, GRIMMINGER, Friedrich, BONAUER, Angelika

“…MicroRNAs (miRs) control various cellular processes in tissue homeostasis and disease by regulating gene expression on the posttranscriptional level. Recently,…”
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Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats by Dahal, Bhola K, Kosanovic, Djuro, Kaulen, Christina, Cornitescu, Teodora, Savai, Rajkumar, Hoffmann, Julia, Reiss, Irwin, Ghofrani, Hossein A, Weissmann, Norbert, Kuebler, Wolfgang M, Seeger, Werner, Grimminger, Friedrich, Schermuly, Ralph T

“…Mast cells (MCs) are implicated in inflammation and tissue remodeling. Accumulation of lung MCs is described in pulmonary hypertension (PH); however, whether…”
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Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation by Raes, G, Brys, L, Dahal, B K, Brandt, J, Grooten, J, Brombacher, F, Vanham, G, Noel, W, Bogaert, P, Boonefaes, T, Kindt, A, Van den Bergh, R, Leenen, PJM, De Baetselier, P, Ghassabeh, G H

“…Molecular markers, especially surface markers associated with type II, cytokine‐dependent, alternatively activated macrophages (aaMF), remain scarce. Besides…”
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Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases by ten Freyhaus, Henrik, Dagnell, Markus, Leuchs, Maike, Vantler, Marius, Berghausen, Eva M, Caglayan, Evren, Weissmann, Norbert, Dahal, Bhola K, Schermuly, Ralph T, Ostman, Arne, Kappert, Kai, Rosenkranz, Stephan

“…Platelet-derived growth factor (PDGF) plays a pivotal role in the pathobiology of pulmonary hypertension (PH) because it promotes pulmonary vascular…”
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Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling by Kojonazarov, Baktybek, Sydykov, Akylbek, Pullamsetti, Soni Savai, Luitel, Himal, Dahal, Bhola K, Kosanovic, Djuro, Tian, Xia, Majewski, Matthaeus, Baumann, Christin, Evans, Steve, Phillips, Peter, Fairman, David, Davie, Neil, Wayman, Chris, Kilty, Iain, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo

“…Abstract Background Little is known about the effects of current PAH therapies and receptor tyrosine kinase inhibitors on heart remodeling. We sought to…”
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Mast Cells and Fibroblasts Work in Concert to Aggravate Pulmonary Fibrosis by Wygrecka, Malgorzata, Dahal, Bhola K, Kosanovic, Djuro, Petersen, Frank, Taborski, Brigitte, von Gerlach, Susanne, Didiasova, Miroslava, Zakrzewicz, Dariusz, Preissner, Klaus T, Schermuly, Ralph T, Markart, Philipp

“…Mast cell (MC) accumulation has been demonstrated in the lungs of idiopathic pulmonary fibrosis (IPF) patients. Mediators released from MCs may regulate tissue…”
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Immune and Inflammatory Cell Involvement in the Pathology of Idiopathic Pulmonary Arterial Hypertension by SAVAI, Rajkumar, PULLAMSETTI, Soni S, KLUSSMANN, Sven, GHOFRANI, Hossein A, WEISSMANN, Norbert, KLEPETKO, Walter, BANAT, Gamal A, SEEGER, Werner, GRIMMINGER, Friedrich, SCHERMULY, Ralph T, KOLBE, Julia, BIENIEK, Ewa, VOSWINCKEL, Robert, FINK, Ludger, SCHEED, Axel, RITTER, Christin, DAHAL, Bhola K, VATER, Axel

“…Pulmonary arterial hypertension (PAH) is characterized by vasoconstriction and vascular remodeling. Recent studies have revealed that immune and inflammatory…”
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Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension by Kosanovic, Djuro, Kojonazarov, Baktybek, Luitel, Himal, Dahal, Bhola K, Sydykov, Akylbek, Cornitescu, Teodora, Janssen, Wiebke, Brandes, Ralf P, Davie, Neil, Ghofrani, Hossein A, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Schermuly, Ralph T

“…Endothelin-1 signalling plays an important role in pathogenesis of pulmonary hypertension. Although different endothelin-A receptor antagonists are developed,…”
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Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane SCF and the PAR-2/PKC-α/Raf-1/p44/42 signaling pathway by Wygrecka, Malgorzata, Dahal, Bhola K, Kosanovic, Djuro, Petersen, Frank, Taborski, Brigitte, von Gerlach, Susanne, Didiasova, Miroslava, Zakrzewicz, Dariusz, Preissner, Klaus T, Schermuly, Ralph T, Markart, Philipp

“…Mast cell (MC) accumulation has been demonstrated in the lungs of idiopathic pulmonary fibrosis (IPF) patients. Mediators released from MCs may regulate tissue…”
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Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction by Egemnazarov, Bakytbek, Schermuly, Ralph T, Dahal, Bhola K, Elliott, Garry T, Hoglen, Niel C, Surber, Mark W, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein A

“…Generalized hypoxic pulmonary vasoconstriction (HPV) occurring during exposure to hypoxia is a detrimental process resulting in an increase in lung vascular…”
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Correction to: Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice by Werner, Franziska, Kojonazarov, Baktybek, Gaßner, Birgit, Abeßer, Marco, Schuh, Kai, Völker, Katharina, Baba, Hideo A., Dahal, Bhola K., Schermuly, Ralph T., Kuhn, Michaela

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Corrigendum to “Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling” [International Journal of Cardiology 167 (2013) 2630–2637] by Kojonazarov, Baktybek, Sydykov, Akylbek, Pullamsetti, Soni Savai, Luitel, Himal, Dahal, Bhola K., Kosanovic, Djuro, Tian, Xia, Majewski, Matthaeus, Baumann, Christin, Evans, Steve, Phillips, Peter, Fairman, David, Davie, Neil, Wayman, Chris, Kilty, Iain, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo

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Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice by Werner, Franziska, Kojonazarov, Baktybek, Gaßner, Birgit, Abeßer, Marco, Schuh, Kai, Völker, Katharina, Baba, Hideo A., Dahal, Bhola K., Schermuly, Ralph T., Kuhn, Michaela

“…The cardiac hormone atrial natriuretic peptide (ANP) regulates systemic and pulmonary arterial blood pressure by activation of its cyclic GMP-producing…”
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Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β by Dahal, Bhola K., Heuchel, Rainer, Pullamsetti, Soni Savai, Wilhelm, Jochen, Ghofrani, Hossein A., Weissmann, Norbert, Seeger, Werner, Grimminger, Friedrich, Schermuly, Ralph T.

“…Platelet-derived growth factor (PDGF) has been implicated in the pathobiology of vascular remodeling. The multikinase inhibitor imatinib that targets PDGF…”
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The peroxisome proliferator–activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy by Kojonazarov, Baktybek, Luitel, Himal, Sydykov, Akylbek, Dahal, Bhola K., Paul-Clark, Mark J., Bonvini, Sara, Reed, Anna, Schermuly, Ralph T., Mitchell, Jane A.

“…Pulmonary hypertension is a debilitating disease with no cure. We have previously shown that peroxisome proliferator–activated receptor (PPAR) β/δ agonists…”
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PAR-2 depletion protects against the development of pulmonary hypertension by Wygrecka, Malgorzata, Markart, Philipp, Marsh, Leigh M, Dahal, Bhola K, Schermuly, Ralph T, Taube, Christian, Meinhardt, Andreas, Ghofrani, Ardeschir, Steinhoff, Martin, Seeger, Werner, Preissner, Klaus T, Weissmann, Norbert, Kwapiszewska, Grazyna

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Abstract 5774: Hypoxia Enhances Platelet-derived Growth Factor Signaling in the Pulmonary Vasculature by HIF-1 α -dependent Downregulation of Protein Tyrosine Phosphatases by Freyhaus, Henrik, Leuchs, Maike, Dagnell, Markus, Vantler, Marius, Caglayan, Evren, Weissmann, Norbert, Schermuly, Ralph T, Dahal, Bhola K, Östman, Arne, Kai, Kappert, Rosenkranz, Stephan

“…Abstract only Background: Platelet-derived growth factor (PDGF) plays a critical role in the development of pulmonary hypertension (PH) as it promotes…”
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Effects of Multikinase inhibitors on pressure overload-induced right ventricular remodelling by Kojonazarov, Baktybek, Sydykov, Akylbek, Pullamsetti, Soni, Luitel, Himal, Dahal, Bhola K, Kosanovic, Djuro, Tian, Xia, Majewski, Matthaeus, Baumann, Christin, Evans, Steve, Phillips, Peter, Fairman, David, Davie, Neil, Wayman, Chris, Kilty, Iain, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein, Schermuly, Ralph

“…Doc number: P37…”
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Genes involved in pulmonary hypertension of mice with endothelial-specific ablation of guanylyl cyclase A by Werner, Franziska, Völker, Katharina, Scholz, Claus-Jürgen, Goebel, Margarethe, Seimetz, Michael, Kojonazarov, Baktybek, Schuh, Kai, Dahal, Bhola K, Schermuly, Ralph T, Oberwinkler, Heike, Gaßner, Birgit, Kuhn, Michaela

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