Search Results - "Dahabieh, Matthew"
-
1
Understanding HIV Latency: The Road to an HIV Cure
Published in Annual review of medicine (01-01-2015)“…Treatment with antiretroviral therapy dramatically increases the survival of HIV-infected individuals. However, treatment has to be continued for life because…”
Get full text
Journal Article -
2
Multimodal Microorganism Development: Integrating Top-Down Biological Engineering with Bottom-Up Rational Design
Published in Trends in biotechnology (Regular ed.) (01-03-2020)“…Biological engineering has unprecedented potential to solve society’s most pressing challenges. Engineering approaches must consider complex technical,…”
Get full text
Journal Article -
3
A Doubly Fluorescent HIV-1 Reporter Shows that the Majority of Integrated HIV-1 Is Latent Shortly after Infection
Published in Journal of Virology (01-04-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
4
Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4 + T cells
Published in eLife (01-05-2018)“…Human immunodeficiency virus (HIV) infection is currently incurable, due to the persistence of latently infected cells. The 'shock and kill' approach to a cure…”
Get full text
Journal Article -
5
Overcoming barriers to innovation in food and agricultural biotechnology
Published in Trends in food science & technology (01-09-2018)“…The food and agricultural biotechnology (FAB) sector is poised to respond to some of society's most pressing challenges, including food security, climate…”
Get full text
Journal Article -
6
The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response
Published in FEBS letters (16-11-2011)“…► Chaetocin, an inhibitor of the Suv39H1 methyltransferase, causes induction of latent HIV-1. ► Treatment with chaetocin does not cause a global T cell…”
Get full text
Journal Article -
7
Industrially Applicable De Novo Lager Yeast Hybrids with a Unique Genomic Architecture: Creation and Characterization
Published in Applied and environmental microbiology (15-01-2021)“…Lager beer is produced by , which is a natural allopolyploid hybrid between and Lager strains are classified into two major groups based largely on genomic…”
Get full text
Journal Article -
8
Direct non-productive HIV-1 infection in a T-cell line is driven by cellular activation state and NFκB
Published in Retrovirology (07-02-2014)“…Molecular latency allows HIV-1 to persist in resting memory CD4+ T-cells as transcriptionally silent provirus integrated into host chromosomal DNA. Multiple…”
Get full text
Journal Article -
9
TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation
Published in Communications biology (23-01-2023)“…Binding of USF1/2 and TFII-I (RBF-2) at conserved sites flanking the HIV-1 LTR enhancer is essential for reactivation from latency in T cells, with TFII-I…”
Get full text
Journal Article -
10
A white-to-opaque-like phenotypic switch in the yeast Torulaspora microellipsoides
Published in Communications biology (28-02-2020)“…Torulaspora microellipsoides is an under-characterized budding yeast of the Saccharomycetaceae family that is primarily associated with viticulture. Here we…”
Get full text
Journal Article -
11
Identification and functional analysis of a second RBF-2 binding site within the HIV-1 promoter
Published in Virology (New York, N.Y.) (15-09-2011)“…Abstract Transcription from the HIV-1 long terminal repeat (LTR) is mediated by numerous host transcription factors. In this study we characterized an E-box…”
Get full text
Journal Article -
12
Functional Expression of the DUR3 Gene in a Wine Yeast Strain to Minimize Ethyl Carbamate in Chardonnay Wine
Published in American journal of enology and viticulture (01-01-2009)Get full text
Journal Article -
13
D-106 Chromatin Functional States Correlate with the Reversal of Latently HIV-1 Infected Primary CD4+ T cells
Published in Journal of acquired immune deficiency syndromes (1999) (01-04-2018)“…Current antiretroviral therapies (ART) do not allow for the eradication of the human immunodeficiency virus (HIV) due to the presence of latent proviruses in…”
Get full text
Journal Article -
14
The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: version 2.0 update
Published in Database : the journal of biological databases and curation (13-05-2013)“…PhosphoGRID is an online database that curates and houses experimentally verified in vivo phosphorylation sites in the Saccharomyces cerevisiae proteome…”
Get full text
Journal Article -
15
Direct non-productive HIV-1 infection in a T-cell line is driven by cellular activation state and NF[kappa]B
Published in Retrovirology (01-01-2014)“…Doc number: 17 Abstract Background: Molecular latency allows HIV-1 to persist in resting memory CD4+ T-cells as transcriptionally silent provirus integrated…”
Get full text
Journal Article -
16
PhosphoGRID: a database of experimentally verified in vivo protein phosphorylation sites from the budding yeast Saccharomyces cerevisiae
Published in Database : the journal of biological databases and curation (01-01-2010)“…Protein phosphorylation plays a central role in cellular regulation. Recent proteomics strategies for identifying phosphopeptides have been developed using the…”
Get full text
Journal Article