Search Results - "Dagrada, G."

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial by Boyd, K D, Ross, F M, Chiecchio, L, Dagrada, G P, Konn, Z J, Tapper, W J, Walker, B A, Wardell, C P, Gregory, W M, Szubert, A J, Bell, S E, Child, J A, Jackson, G H, Davies, F E, Morgan, G J

“…The association of genetic lesions detected by fluorescence in situ hybridization (FISH) with survival was analyzed in 1069 patients with newly presenting…”
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A phase II study of sorafenib in recurrent and/or metastatic salivary gland carcinomas: Translational analyses and clinical impact by Locati, L.D, Perrone, F, Cortelazzi, B, Bergamini, C, Bossi, P, Civelli, E, Morosi, C, Lo Vullo, S, Imbimbo, M, Quattrone, P, Dagrada, G.P, Granata, R, Resteghini, C, Mirabile, A, Alfieri, S, Orlandi, E, Mariani, L, Saibene, G, Pilotti, S, Licitra, L

“…Abstract Background Pre-clinical and clinical evidence suggests a rationale for the use of anti-angiogenic agents, including sorafenib, in recurrent and/or…”
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Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study by Stacchiotti, S., Simeone, N., Lo Vullo, S., Morosi, C., Greco, F.G., Gronchi, A., Barisella, M., Collini, P., Zaffaroni, N., Dagrada, G.P., Frezza, A.M., Mariani, L., Casali, P.G.

“…To explore the activity of axitinib in advanced solitary fibrous tumour (SFT). In this investigator-driven phase II study on axitinib in advanced and…”
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Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour by Stacchiotti, S, Tortoreto, M, Baldi, G.G, Grignani, G, Toss, A, Badalamenti, G, Cominetti, D, Morosi, C, Dei Tos, A.P, Festinese, F, Fumagalli, E, Provenzano, S, Gronchi, A, Pennacchioli, E, Negri, T, Dagrada, G.P, Spagnuolo, R.D, Pilotti, S, Casali, P.G, Zaffaroni, N

“…Abstract Background To explore the activity of pazopanib in solitary fibrous tumour (SFT). Patients and methods In a preclinical study, we compared the…”
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Activity of sunitinib in extraskeletal myxoid chondrosarcoma by Stacchiotti, S, Pantaleo, M.A, Astolfi, A, Dagrada, G.P, Negri, T, Dei Tos, A.P, Indio, V, Morosi, C, Gronchi, A, Colombo, C, Conca, E, Toffolatti, L, Tazzari, M, Crippa, F, Maestro, R, Pilotti, S, Casali, P.G

“…Abstract Background Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma, marked by NR4A3 rearrangement. Herein we report on the activity of…”
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Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highlight the potential effectiveness of trabectedin or eribulin against this tumour by Stacchiotti, S, Saponara, M, Frapolli, R, Tortoreto, M, Cominetti, D, Provenzano, S, Negri, T, Dagrada, G.P, Gronchi, A, Colombo, C, Vincenzi, B, Badalamenti, G, Zuco, V, Renne, S.L, Collini, P, Morosi, C, Dei Tos, A.P, Bello, E, Pilotti, S, Casali, P.G, D'Incalci, M, Zaffaroni, N

“…Abstract Background Preclinical models that mimic pathological and molecular features of solitary fibrous tumour (SFT) represent an important tool to select…”
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Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment by Tazzari, Marcella, Indio, Valentina, Vergani, Barbara, De Cecco, Loris, Rini, Francesca, Negri, Tiziana, Camisaschi, Chiara, Fiore, Marco, Stacchiotti, Silvia, Dagrada, G. Paolo, Casali, Paolo G., Gronchi, Alessandro, Astolfi, Annalisa, Pantaleo, Maria A., Villa, Antonello, Lombardo, Claudia, Arienti, Flavio, Pilotti, Silvana, Rivoltini, Licia, Castelli, Chiara

“…Dermatofibrosarcoma protuberans (DFSP), although rare, is the most frequent skin sarcoma. Here, we focus on DFSP carrying the fibrosarcomatous transformation…”
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Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma by CHIECCHIO, L, PROTHEROE, R. K. M, ORCHARD, K. H, HARRISON, C. J, CROSS, N. C. P, MORGAN, G. J, ROSS, F. M, IBRAHIM, A. H, CHEUNG, K. L, RUDDUCK, C, DAGRADA, G. P, CABANAS, E. D, PARKER, T, NIGHTINGALE, M, WECHALEKAR, A

“…In myeloma, the prognostic impact of different strategies used to detect chromosome 13 deletion (Delta13) remains controversial. To address this, we compared…”
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Mechanism of action of trabectedin in desmoplastic small round cell tumor cells by Uboldi, S, Craparotta, I, Colella, G, Ronchetti, E, Beltrame, L, Vicario, S, Marchini, S, Panini, N, Dagrada, G, Bozzi, F, Pilotti, S, Galmarini, C M, D'Incalci, M, Gatta, R

“…Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive disease, that can be described as a member of the family of small round blue cell…”
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Absence of ALK and MET alterations in head and neck sarcomatoid carcinoma by Perrone, F, Bossi, P, Cortelazzi, B, Dagrada, G.P, Paielli, N, Licitra, L, Pilotti, S

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PDGFRα, PDGFRβ and KIT expression/activation in conventional chondrosarcoma by Lagonigro, MS, Tamborini, E, Negri, T, Staurengo, S, Dagrada, GP, Miselli, F, Gabanti, E, Greco, A, Casali, PG, Carbone, A, Pierotti, MA, Pilotti, S

“…Chondrosarcomas represent 20% of all primary bone sarcomas, and many studies have attempted to unravel molecular targets for future development of new…”
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Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context by CHIECCHIO, Laura, PAOLO DAGRADA, Gian, IBRAHIM, Ashraf H, DACHS CABANAS, Elizabet, PROTHEROE, Rebecca K. M, STOCKLEY, David M, ORCHARD, Kim H, CROSS, Nicholas C. P, HARRISON, Christine J, ROSS, Fiona M

“…Multiple myeloma, monoclonal gammopathy of undetermined significance and smoldering multiple myeloma harbor common chromosomal abnormalities but the prevalence…”
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Expression of HER-2/neu gene and protein in salivary duct carcinomas of parotid gland as revealed by fluorescence in-situ hybridization and immunohistochemistry by Dagrada, G P, Negri, T, Tamborini, E, Pierotti, M A, Pilotti, S

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Herceptin ® plus chemotherapy in relapsed and/or metastatic salivary gland cancer by Locati, L.D., Rinaldi, G., Bossi, P., Dagrada, G.P., Quattrone, P., Cantú, G., Licitra, L.

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Immunophenotypic and genotypic analysis of a case of primary peripheral primitive neuroectodermal tumour (pPNET) of the urinary bladder by Colecchia, M, Dagrada, G P, Poliani, P L, Pilotti, S

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Tazemetostat and doxorubicin in patient-derived preclinical models of epithelioid sarcoma (ES) by Pasquali, S., Arrighetti, N., Zuco, V., Tortoreto, M., Soffientini, C., Sigalotti, L., Maestro, R., Percio, S., Barisella, M., Collini, P., Dagrada, G., Frezza, A.M., Gronchi, A., Stacchiotti, S., Zaffaroni, N.

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Detection of bladder cancer by multitarget multicolour FISH: comparative analysis on archival cytology and paraffin-embedded tissue by Mezzelani, A., Dagrada, G., Alasio, L., Sozzi, G., Pilotti, S.

“…Detection of bladder cancer by multitarget multicolour FISH: comparative analysis on archival cytology and paraffin‐embedded tissue We have evaluated the…”
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Solitary fibrous tumour presenting with a single bone metastasis: report of six cases and literature review by Colia, Vittoria, Provenzano, Salvatore, Morosi, Carlo, Collini, Paola, Renne, Salvatore Lorenzo, Dagrada, Paolo G, Sangalli, Claudia, Dei Tos, Angelo Paolo, Marrari, Andrea, Casali, Paolo G, Stacchiotti, Silvia

“…Solitary fibrous tumour (SFT) is a rare soft tissue sarcoma with a low metastatic potential. A higher metastatic rate is observed in the…”
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1721PMyoepithelial tumours of soft tissues and extraskeletal myxoid chondrosarcomas feature a distinct transcriptional pattern by Racanelli, D, Stacchiotti, S, Brenca, M, Sbaraglia, M, Fassetta, K, Baldazzi, D, Piccinin, S, Brich, S, Casali, P G, Collini, P, Dagrada, G P, Fiore, M, Gronchi, A, Astolfi, A, Pantaleo, M A, Righi, A, Pilotti, S, Tos, A P Dei, Maestro, R

“…Abstract Background Myoepithelial tumors of soft tissues (MT) and Extraskeletal Myxoid Chondrosarcoma (EMC) are closely related pathological entities whose…”
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SYT-SSX fusion transcripts and epithelial differentiation in synovial sarcoma by Mezzelani, A, Dagrada, G P, Sozzi, G, Pierotti, M A, Pilotti, S

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