Search Results - "Dagher, Tracy"

Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm by Poisson, Johanne, Tanguy, Marion, Davy, Hortense, Camara, Fatoumata, El Mdawar, Marie-Belle, Kheloufi, Marouane, Dagher, Tracy, Devue, Cécile, Lasselin, Juliette, Plessier, Aurélie, Merchant, Salma, Blanc-Brude, Olivier, Souyri, Michèle, Mougenot, Nathalie, Dingli, Florent, Loew, Damarys, Hatem, Stephane N, James, Chloé, Villeval, Jean-Luc, Boulanger, Chantal M, Rautou, Pierre-Emmanuel

“…Arterial cardiovascular events are the leading cause of death in patients with JAK2V617F myeloproliferative neoplasms (MPNs). However, their mechanisms are…”
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Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis by Buks, Ralfs, Dagher, Tracy, Rotordam, Maria, Monedero Alonso, David, Cochet, Sylvie, Gautier, Emilie-Fleur, Chafey, Philippe, Cassinat, Bruno, Kiladjian, Jean-Jacques, Becker, Nadine, Plo, Isabelle, Egée, Stéphane, El Nemer, Wassim

“…Over 95% of Polycythemia Vera (PV) patients carry the V617F mutation in the tyrosine kinase Janus kinase 2 (JAK2), resulting in uncontrolled erythroid…”
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SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice by Willekens, Christophe, Laplane, Lucie, Dagher, Tracy, Benlabiod, Camelia, Papadopoulos, Nicolas, Lacout, Catherine, Rameau, Philippe, Catelain, Cyril, Alfaro, Alexia, Edmond, Valérie, Signolle, Nicolas, Marchand, Valentine, Droin, Nathalie, Hoogenboezem, Remco, Schneider, Rebekka K., Penson, Alex, Abdel-Wahab, Omar, Giraudier, Stephane, Pasquier, Florence, Marty, Caroline, Plo, Isabelle, Villeval, Jean-Luc, Constantinescu, Stefan N., Porteu, Françoise, Vainchenker, William, Solary, Eric

“…Heterozygous mutation targeting proline 95 in Serine/Arginine-rich Splicing Factor 2 (SRSF2) is associated with V617F mutation in Janus Activated Kinase 2…”
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JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML by Dagher, Tracy, Maslah, Nabih, Edmond, Valérie, Cassinat, Bruno, Vainchenker, William, Giraudier, Stéphane, Pasquier, Florence, Verger, Emmanuelle, Niwa-Kawakita, Michiko, Lallemand-Breitenbach, Valérie, Plo, Isabelle, Kiladjian, Jean-Jacques, Villeval, Jean-Luc, de Thé, Hugues

“…Interferon α (IFNα) is used to treat JAK2V617F-driven myeloproliferative neoplasms (MPNs) but rarely clears the disease. We investigated the IFNα mechanism of…”
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Lessons from mouse models of MPN by Benlabiod, Camelia, Dagher, Tracy, Marty, Caroline, Villeval, Jean-Luc

“…Over the past decades, a variety of MPN mouse models have been developed to express in HSC the main mutations identified in patients: JAK2 , CALRdel52 or ins5…”
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SRSF2-P95Hdelays Myelofibrosis Development through Altered JAK/STAT Signaling in JAK2-V617F Megakaryocytes by Willekens, Christophe, Laplane, Lucie, Dagher, Tracy, Benlabiod, Camélia, Lacout, Catherine, Rameau, Philippe, Catelain, Cyril, Alfaro, Alexia, Edmond, Valérie, Signolle, Nicolas, Silvin, Aymeric, Ginhoux, Florent, Marchand, Valentine, Droin, Nathalie, Hoogenboezem, Remco, Schneider, Rebekka K., Penson, Alexander V, Abdel-Wahab, Omar, Gonin, Patrick, Marty, Caroline, Plo, Isabelle, Villeval, Jean-Luc, Porteu, Francoise, Vainchenker, William, Solary, Eric

“…Background: The gain-of-function JAK2 V617F mutant is the most common driver mutation identified in myeloproliferative neoplasms (MPNs). Additional somatic…”
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Specific and Synergistic Targeting of JAK2V617F Cells By Interferon Alpha and Arsenic by Maslahl, Nabih, Dagher, Tracy, Edmond, Valérie, Cassinat, Bruno, Lallemand-Breitenbach, Valérie, Verger, Emmanuelle, Plo, Isabelle, Kiladjian, Jean-Jacques, Villeval, Jean-Luc, de Thé, Hugues

“…N.M. and T.D. co-first authors, J.L.V. and Hd.T. co-last authors Introduction: We have shown in clinical trials and preclinical studies on Myeloproliferative…”
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1017 – INVESTIGATING THE MECHANISMS OF IFNALPHA THERAPY IN JAK2V617F AND CALR MUTATED MYELOPROLIFERATIVE NEOPLASMS by PLO, Isabelle, Tisserand, Amandine, Noble, Robert, Dagher, Tracy, Maslah, Nabih, Mosca, Matthieu, Edmond, Valérie, Marzac, Christophe, Cassinat, Bruno, Marty, Caroline, Pasquier, Florence, Raslova, Hana, Constantinescu, Stefan, Girodon, François, Hochberg, Michael, de Thé, Hugues, Kiladjian, Jean Jacques, Villeval, Jean-Luc, Vainchenker, William

“…Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) are acquired clonal disorders of hematopoietic stem cells (HSC) leading to the hyperplasia of one…”
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Erythrocyte-derived microvesicles induce arterial spasms in [JAK2.sup.V617F] myeloproliferative neoplasm by Poisson, Johanne, Tanguy, Marion, Davy, Hortense, Camara, Fatoumata, Mdawar, Marie-Belle El, Kheloufi, Marouane, Dagher, Tracy, Devue, Cecile, Lasselin, Juliette, Plessier, Aurelie, Merchant, Salma, Blanc-Brude, Olivier, Souyri, Michele, Dingli, Nathalie MougenoFlorent, Loew, Damarys, Hatem, Stephane N, James, Chloe, Villeval, Jean-Luc, Boulanger, Chantal M, Rautou, Pierre-Emmanuel

“…Arterial cardiovascular events are the leading cause of death in patients with [JAK2.sup.V617F] myeloproliferative neoplasms (MPNs). However, their mechanisms…”
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Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm by Poisson, Johanne, Tanguy, Marion, Davy, Hortense, Camara, Fatoumata, El Mdawar, Marie-Belle, Kheloufi, Marouane, Dagher, Tracy, Devue, Cecile, Lasselin, Juliette, Plessier, Aurélie, Merchant, Salma, Blanc-Brude, Olivier, Souyri, Michèle, Mougenot, Nathalie, Dingli, Florent, Loew, Damarys, Hatem, Stephane N., James, Chloé, Villeval, Jean-Luc, Boulanger, Chantal M., Rautou, Pierre-Emmanuel

“…Arterial cardiovascular events are the leading cause of death in patients with JAK2V617F myeloproliferative neoplasms (MPN). However, their mechanisms are…”
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Differential Impact of Interferon Alpha on JAK2V617F and Calr Mutated Hematopoietic Stem and Progenitor Cells in Classical MPN by Mosca, Matthieu, Lamrani, Lamia, Marzac, Christophe, Tisserand, Amandine, Edmond, Valérie, Dagher, Tracy, El-Khoury, Mira, Marty, Caroline, Campario, Hugo, Casadevall, Nicole, Solary, Eric, Raslova, Hana, Cassinat, Bruno, Constantinescu, Stefan N, Kiladjian, Jean-Jacques, Girodon, Francois, Villeval, Jean-Luc, Vainchenker, William, Plo, Isabelle

“…Introduction: Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) include Polycythemia Vera (PV), Essential Thrombocytemia (ET) and Primary…”
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Comparison of endothelial promoter efficiency and specificity in mice reveals a subset of Pdgfb‐positive hematopoietic cells by Poisson, Johanne, Tanguy, Marion, Davy, Hortense, Camara, Fatoumata, El Mdawar, Marie-Belle, Kheloufi, Marouane, Dagher, Tracy, Devue, Cécile, Lasselin, Juliette, Plessier, Aurélie, Merchant, Salma, Blanc-Brude, Olivier, Souyri, Michèle, Mougenot, Nathalie, Dingli, Florent, Loew, Damarys, Hatem, Stephane, James, Chloé, Villeval, Jean-Luc, Boulanger, Chantal, Rautou, Pierre-Emmanuel

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Altered Ca 2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis by Buks, Ralfs, Dagher, Tracy, Rotordam, Maria Giustina, Monedero Alonso, David, Cochet, Sylvie, Gautier, Emilie-Fleur, Chafey, Philippe, Cassinat, Bruno, Kiladjian, Jean-Jacques, Becker, Nadine, Plo, Isabelle, Egée, Stéphane, El Nemer, Wassim

“…Over 95% of Polycythemia Vera (PV) patients carry the V617F mutation in the tyrosine kinase Janus kinase 2 (JAK2), resulting in uncontrolled erythroid…”
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