Search Results - "Dafydd, Derfel Ap"

Interpretability of radiomics models is improved when using feature group selection strategies for predicting molecular and clinical targets in clear-cell renal cell carcinoma: insights from the TRACERx Renal study by Orton, Matthew R, Hann, Evan, Doran, Simon J, Shepherd, Scott T C, Ap Dafydd, Derfel, Spencer, Charlotte E, López, José I, Albarrán-Artahona, Víctor, Comito, Francesca, Warren, Hannah, Shur, Joshua, Messiou, Christina, Larkin, James, Turajlic, Samra, Koh, Dow-Mu

“…The aim of this work is to evaluate the performance of radiomics predictions for a range of molecular, genomic and clinical targets in patients with clear cell…”
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Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study by Fu, Xiao, Zhao, Yue, Lopez, Jose I., Rowan, Andrew, Au, Lewis, Fendler, Annika, Hazell, Steve, Xu, Hang, Horswell, Stuart, Shepherd, Scott T. C., Spencer, Charlotte E., Spain, Lavinia, Byrne, Fiona, Stamp, Gordon, O’Brien, Tim, Nicol, David, Augustine, Marcellus, Chandra, Ashish, Rudman, Sarah, Toncheva, Antonia, Furness, Andrew J. S., Pickering, Lisa, Kumar, Santosh, Koh, Dow-Mu, Messiou, Christina, Dafydd, Derfel ap, Orton, Matthew R., Doran, Simon J., Larkin, James, Swanton, Charles, Sahai, Erik, Litchfield, Kevin, Turajlic, Samra, Bates, Paul A.

“…Genetic intra-tumour heterogeneity fuels clonal evolution, but our understanding of clinically relevant clonal dynamics remain limited. We investigated spatial…”
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Saline‐aided ultrasound‐guided transoral biopsy of retropharyngeal nodes in head and neck cancer: A feasibility study of five patients by Ghedia, Reshma, Hariri, Ahmad, Lee, Ying Ki, Dragan, Alina, Paleri, Vinidh, Ap Dafydd, Derfel

“…Background The purpose of this study was to determine the feasibility of the novel technique of intra‐cavitary saline‐aided ultrasound (US) guided transoral…”
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Head and neck mucosal melanoma: The United Kingdom national guidelines by Nenclares, Pablo, Ap Dafydd, Derfel, Bagwan, Izhar, Begg, Donna, Kerawala, Cyrus, King, Emma, Lingley, Ken, Paleri, Vinidh, Paterson, Gillian, Payne, Miranda, Silva, Priyamal, Steven, Neil, Turnbull, Nancy, Yip, Kent, Harrington, Kevin J.

“…The United Kingdom head and neck mucosal melanoma guideline development group used an evidence-based systematic approach to make recommendations in key areas…”
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Interobserver variation in clinical target volume (CTV) delineation for stereotactic radiotherapy to non-spinal bone metastases in prostate cancer: CT, MRI and PET/CT fusion by Chapman, Ewan Richard, Nicholls, Luke, Suh, Yae-Eun, Khoo, Vincent, Levine, Daniel, ap Dafydd, Derfel, Van As, Nicholas

“…•MRI fusion alone does not significantly impact inter-observer variability in the delineation of prostate cancer bone metastases.•Significant improvements in…”
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Head and neck mucosal melanoma: radiological considerations and UK imaging guidelines by Algudkar, Ashwin, Harrington, Kevin, Kerawala, Cyrus, Bagwan, Izhar, ap Dafydd, Derfel

“…Purpose Awareness of head and neck mucosal melanoma (HNMM) is important, as incorrect work-up can impact on the investigation and management of this rare and…”
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Response Evaluation Criteria in Gastrointestinal and Abdominal Cancers: Which to Use and How to Measure by Castagnoli, Francesca, Mencel, Justin, Ap Dafydd, Derfel, Gough, Jessica, Drake, Brent, Mcaddy, Naami Charlotte, Withey, Samuel Joseph, Riddell, Angela Mary, Koh, Dow-Mu, Shur, Joshua David

“…As the management of gastrointestinal malignancy has evolved, tumor response assessment has expanded from size-based assessments to those that include tumor…”
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A Review of Contemporary Image Guidance Techniques in Head and Neck Cancer by Alade, Adebayo, Persad, Melissa, Bitar, George, Dragan, Alina, Fotiadis, Nicos, Shur, Joshua, Wong, Kee Howe, Ng‐Cheng‐Hin, Brian, Paleri, Vinidh, Harrington, Kevin, Dafydd, Derfel Ap

“…Traditional head and neck cancer treatment involves open surgery, cytotoxic chemotherapy, and conventional radiotherapy planning. Emerging techniques aim to…”
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What is the role of the surgeon in the management of head and neck mucosal melanoma in the immunotherapy era? by Edmond, Mark, Nenclares, Pablo, Harrington, Kevin, Ap Dafydd, Derfel, Bagwan, Izhar, Begg, Donna, Lingley, Ken, Patterson, Gillian, Payne, Miranda, Steven, Neil, Turnbull, Nancy, Yip, Kent, Silva, Priyamal, Kerawala, Cyrus, Paleri, Vinidh, King, Emma

“…Introduction The advent of immunotherapy has impacted both the management and, to a lesser extent, the outcomes for patients with head and neck mucosal…”
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Ultrasound-guided intra-tumoral administration of directly-injected therapies: a review of the technical and logistical considerations by Bitar, George Gabriel, Persad, Melissa, Dragan, Alina, Alade, Adebayo, Jiménez-Labaig, Pablo, Johnston, Edward, Withey, Samuel J, Fotiadis, Nicos, Harrington, Kevin J, Ap Dafydd, Derfel

“…Directly-injected therapies (DIT) include a broad range of agents within a developing research field in cancer immunotherapy, with encouraging clinical trial…”
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Paratesticular Sarcoma: Typical Presentation, Imaging Features and Clinical Challenges by ap Dafydd, Derfel, MRCP FRCR, Messiou, Christina, MD MRCP FRCR, Thway, Khin, MD FRCPath, Strauss, Dirk C, MMed(Surg), FCS(SA), FRCS(Gen), Nicol, David L, MBBS FRACS, Moskovic, Eleanor, FRCP FRCR

“…Abstract Objective To describe the major imaging features, together with clinical data, of paratesticular sarcomas. Methods A retrospective analysis was…”
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On-treatment immune prognostic score for patients with relapsed and/or metastatic head and neck squamous cell carcinoma treated with immunotherapy by Nenclares, Pablo, Gunn, Lucinda, Soliman, Heba, Bover, Mateo, Trinh, Amy, Leslie, Isla, Wong, Kee Howe, Melcher, Alan, Newbold, Kate, Nutting, Chris M, ap Dafydd, Derfel, Bhide, Shreerang A, Harrington, Kevin

“…BackgroundPrevious studies have suggested that inflammatory markers (neutrophil-to-lymphocyte ratio (NLR), lactate dehydrogenase (LDH) and fibrinogen) are…”
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Integrated surgery and radiology: trans-oral robotic surgery guided by real-time radiologist-operated intraoral ultrasound by Green, Edward D., Paleri, Vinidh, Hardman, John C., Kerawala, Cyrus, Riva, Francesco M. G., Jaly, Alaa A., ap Dafydd, Derfel

“…Purpose We aimed to evaluate the feasibility and utility of intraoral ultrasound as a real-time guidance technique in trans-oral robotic surgery (TORS)…”
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Service contribution and cost-effectiveness of specialist registrars in NHS trusts: a survey and costing analysis by Dafydd, Derfel ap, Baskaradas, Aroon, Bobdiwala, Shabnam, Anwar, Muhammad Saleem, Abrahams, Rachel, Jeremy, Levy

“…Since the introduction of the European Working Time Directive, specialist registrars arguably contribute less to clinical service. The purpose of this study…”
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Service contribution and cost-effectiveness of specialist registrars in NHS trusts: a survey and costing analysis by Dafydd, Derfel Ap, Baskaradas, Aroon, Bobdiwala, Shabnam, Anwar, Muhammad Saleem, Abrahams, Rachel, Jeremy, Levy

“…Since the introduction of the European Working Time Directive, specialist registrars arguably contribute less to clinical service. The purpose of this study…”
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Development of training-related health care software by a team of clinical educators: their experience, from conception to piloting by Ap Dafydd, Derfel, Williamson, Ruth, Blunt, Philip, Blunt, Dominic M

“…The difficulties of producing useful, bespoke, and affordable information technology systems for large health care organizations are well publicized, following…”
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Radiomics in Oncology: A Practical Guide by Shur, Joshua D., Doran, Simon J., Kumar, Santosh, ap Dafydd, Derfel, Downey, Kate, O’Connor, James P. B., Papanikolaou, Nikolaos, Messiou, Christina, Koh, Dow-Mu, Orton, Matthew R.

“…Radiomics refers to the extraction of mineable data from medical imaging and has been applied within oncology to improve diagnosis, prognostication, and…”
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Incidentally detected 18F-FDG PET-CT-avid thyroid nodules in patients with advanced malignancy: long-term oncological outcomes from a single-centre retrospective cohort by Owens, Cara, Fitzhugh, Alex, Harrington, Kevin, Paleri, Vinidh, Sharma, Bhupinder, Shur, Joshua, ap Dafydd, Derfel

“…Thyroid nodules are frequently detected incidentally on 18F-fluorodeoxyglucose PET-computed tomography (18F-FDG PET-CT) studies and may prompt, further, often…”
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2159: SBRT versus RFA: Baseline characteristics and outcomes in patients with lung metastases by Tong, Daniel, Pang, Jennifer, Fotiadis, Nicos, Satchwell, Laura, Rajan, Zayn, Emarah, Mohammad, Bashir, Usman, Dafydd, Derfel ap, McCall, James, Cunningham, David, Ahmed, Merina

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Intratumoral therapies in head and neck squamous cell carcinoma: A systematic review and future perspectives by Jiménez-Labaig, Pablo, Rullan, Antonio, Braña, Irene, Hernando-Calvo, Alberto, Moreno, Victor, Doger, Bernard, Bitar, George, Ap Dafydd, Derfel, Melcher, Alan, Harrington, Kevin J.

“…•Head and neck squamous cell carcinoma presents an ideal scenario for intratumoral therapies, due to its local recurrence pattern and frequent superficial…”
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