Search Results - "Dafoe, Donald C."
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The Role of Oxidative Stress in Pancreatic β Cell Dysfunction in Diabetes
Published in International journal of molecular sciences (03-02-2021)“…Diabetes is a chronic metabolic disorder characterized by inappropriately elevated glucose levels as a result of impaired pancreatic β cell function and…”
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2
Current Management of Patients With Acquired Solitary Kidney
Published in Kidney international reports (01-09-2019)“…Persons with acquired solitary kidney, including those who have had a unilateral nephrectomy for living kidney donation, renal malignancies, or trauma, have…”
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Approach and Management of Hypertension After Kidney Transplantation
Published in Frontiers in medicine (16-06-2020)“…Hypertension is one of the most common cardiovascular co-morbidities after successful kidney transplantation. It commonly occurs in patients with other…”
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4
Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells
Published in Diabetologia (01-11-2016)“…Aims/hypothesis Endothelial cells (ECs) play an essential role in pancreatic organogenesis. We hypothesise that effective in vitro interactions between human…”
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Towards a Rational Balanced Pancreatic and Islet Allocation Schema
Published in Cell transplantation (2021)“…Allocation of donated organs for transplantation is a complex process that considers numerous factors such as donor, organ and candidate characteristics and…”
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Current Pharmacological Intervention and Medical Management for Diabetic Kidney Transplant Recipients
Published in Pharmaceutics (19-03-2021)“…Hyperglycemia after kidney transplantation is common in both diabetic and non-diabetic patients. Both pretransplant and post-transplant diabetes mellitus are…”
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Endothelial Cells in Co-culture Enhance Embryonic Stem Cell Differentiation to Pancreatic Progenitors and Insulin-Producing Cells through BMP Signaling
Published in Stem cell reviews (01-09-2011)“…Endothelial cells (ECs) represent the major component of the embryonic pancreatic niche and play a key role in the differentiation of insulin-producing β cells…”
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Necrotizing fasciitis
Published in Chest (01-07-1996)“…Necrotizing fasciitis is an uncommon soft-tissue infection, usually caused by toxin-producing, virulent bacteria, which is characterized by widespread fascial…”
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Precision Medicine and Personalized Approach to Renal Transplantation
Published in Seminars in nephrology (01-07-2018)“…Successful renal transplantation is a highly effective endeavor that improves and prolongs the lives of patients with chronic kidney disease. Transplant…”
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Is It Time to Utilize Genetic Testing for Living Kidney Donor Evaluation?
Published in Nephron (2015) (01-03-2022)“…Living donor kidney transplantation is an effective strategy to mitigate the challenges of solid organ shortage. However, being a living kidney donor is not…”
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Hyponatremia: A possible immuno‐neuroendocrine interface with COVID‐19 in a kidney transplant recipient
Published in Transplant infectious disease (01-12-2020)“…There is fast‐emerging, cumulative clinical data on coronavirus disease 2019 (COVID‐19) in kidney transplant recipients. Although respiratory tract symptoms…”
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12
Novel options for failing allograft in kidney transplanted patients to avoid or defer dialysis therapy
Published in Current opinion in nephrology and hypertension (01-01-2020)“…PURPOSE OF REVIEWDespite improvement in short-term renal allograft survival in recent years, renal transplant recipients (RTR) have poorer long-term allograft…”
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13
Haddon matrix for kidney transplantation during COVID‐19 pandemic: A problem solving framework for present and future
Published in Transplant infectious disease (01-12-2020)Get full text
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14
Erratum to: Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells
Published in Diabetologia (01-12-2016)Get full text
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15
Inflammatory biomarkers in the blood and pancreatic tissue of organ donors that predict human islet isolation success and function
Published in Islets (02-01-2020)“…The pancreas of brain-dead donors is the primary source of islets for transplantation. However, brain death mediates systemic inflammation, which may affect…”
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16
Leptin enhances endothelial cell differentiation and angiogenesis in murine embryonic stem cells
Published in Microvascular research (01-01-2015)“…The metabolic regulation of leptin and its angiogenic effects have been well characterized in adult mammals. However, the role of leptin in the differentiation…”
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Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation
Published in Stem cells and development (15-12-2013)“…Endothelial cells (ECs) provide inductive signals for cell differentiation in vivo. However, it is unknown if these cells promote such differentiation in vitro…”
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Kidney allograft infarction associated with transplant renal artery stenosis in a COVID-19 kidney transplant recipient
Published in Clinical nephrology. Case studies (01-01-2021)“…Kidney allograft infarction is rare, but an urgent condition that requires prompt intervention to avoid allograft loss. Renal artery thrombosis is the leading…”
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19
Characterization of microvascular endothelial cells isolated from the dermis of adult mouse tails
Published in Microvascular research (01-09-2011)“…Dermal microvascular endothelial cells (DMECs) play an important role in physiological and pathophysiological processes such as wound healing, cell…”
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Osteopontin Protects the Islets and β-Cells from Interleukin-1 β-Mediated Cytotoxicity through Negative Feedback Regulation of Nitric Oxide
Published in Endocrinology (Philadelphia) (01-02-2007)“…Osteopontin (OPN), a phosphorylated glycoprotein that binds to an integrin-binding motif, has been shown to regulate nitric oxide (NO) production via…”
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