Search Results - "Daeumer, M"

Respiratory syncytial virus A in haematological patients with prolonged shedding: Premature stop codons and deletion of the genotype ON1 72-nucleotide-duplication in the attachment G gene by Tabatabai, J., Thielen, A., Lehners, N., Daeumer, M., Schnitzler, P.

“…•RSV strains in haematological patients with prolonged shedding are analysed.•Phylogenetic analysis identified RSV A genotypes NA1 and ON1.•Genetic variability…”
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High efficacy of sofosbuvir/velpatasvir and impact of baseline resistance‐associated substitutions in hepatitis C genotype 3 infection by von Felden, J., Vermehren, J., Ingiliz, P., Mauss, S., Lutz, T., Simon, K. G., Busch, H. W., Baumgarten, A., Schewe, K., Hueppe, D., Boesecke, C., Rockstroh, J. K., Daeumer, M., Luebke, N., Timm, J., Schulze zur Wiesch, J., Sarrazin, C., Christensen, S.

“…Summary Background Twelve weeks of the pangenotypic direct‐acting antiviral (DAA) combination sofosbuvir/velpatasvir (SOF/VEL) was highly efficient in patients…”
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Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B by Beggel, B., Münk, C., Däumer, M., Hauck, K., Häussinger, D., Lengauer, T., Erhardt, A.

“…Summary Human APOBEC3 (A3) cytosine deaminases are antiviral restriction factors capable of editing the genome the hepatitis B virus (HBV). Despite the…”
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Hepatitis C Virus Screening Project of Patients on Current Anti-HCV Therapy by Knops, E, Kalaghatgi, P, Neumann-Fraune, M, Heger, E, Schuelter, E, Lengauer, T, Keitel, V, Goeser, T, Schuebel, N, von Hahn, T, Peuser, I, Qurishi, N, Römer, K, Scholten, S, Daeumer, M, zur Wiesch, J.S, Baumgarten, A, Obermeier, M, Walter, H, Kaiser, R, Sierra, S

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27 Therapeutic immune recovery prevents emergence of CXCR4-tropic HIV-1 by J. Bader, M. Daeumer, A. Thielen, F. Schoni-Affolter, J. Boeni, M. Gorgievski-Hrisoho, G. Martinetti, T. Klimkait

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Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes by Beerenwinkel, Niko, Däumer, Martin, Oette, Mark, Korn, Klaus, Hoffmann, Daniel, Kaiser, Rolf, Lengauer, Thomas, Selbig, Joachim, Walter, Hauke

“…Therapeutic success of anti-HIV therapies is limited by the development of drug resistant viruses. These genetic variants display complex mutational patterns…”
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THU-221 - Hepatitis C Virus Screening Project of Patients on Current Anti-HCV Therapy by Knops, E., Kalaghatgi, P., Neumann-Fraune, M., Heger, E., Schuelter, E., Lengauer, T., Keitel, V., Goeser, T., Schuebel, N., von Hahn, T., Peuser, I., Qurishi, N., Römer, K., Scholten, S., Daeumer, M., zur Wiesch, J.S., Baumgarten, A., Obermeier, M., Walter, H., Kaiser, R., Sierra, S.

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Estimating HIV Evolutionary Pathways and the Genetic Barrier to Drug Resistance by Beerenwinkel, Niko, Däumer, Martin, Sing, Tobias, Rahnenführer, Jörg, Lengauer, Thomas, Selbig, Joachim, Hoffmann, Daniel, Kaiser, Rolf

“…BackgroundThe evolution of drug-resistant viruses challenges the management of human immunodeficiency virus (HIV) infections. Understanding this evolutionary…”
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Predicting the Response to Combination Antiretroviral Therapy: Retrospective Validation of geno2pheno-THEO on a Large Clinical Database by Altmann, André, Däumer, Martin, Beerenwinkel, Niko, Peres, Yardena, Schülter, Eugen, Büch, Joachim, Rhee, Soo-Yon, Sönnerborg, Anders, Fessel, W. Jeffrey, Shafer, Robert W., Zazzi, Maurizio, Kaiser, Rolf, Lengauer, Thomas

“…BackgroundExpert-based genotypic interpretation systems are standard methods for guiding treatment selection for patients infected with human immunodeficiency…”
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Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants: Virology by Noguera-Julian, M, Cozzi-Lepri, A, Di Giallonardo, F, Schuurman, R, Daeumer, M, Aitken, S, Ceccherini-Silberstein, F, D'Arminio Monforte, A, Geretti, A M, Booth, CL, Kaiser, R, Michalik, C, Jansen, K, Masquelier, B, Bellecave, P, Kouyos, R D, Castro, E, Furrer, H, Schultze, A, Guenthard, H F, Brun-Vezinet, F, Metzner, K J, Paredes, R, Paredes, Roger, Metzner, Karin J, Cozzi-Lepri, Alessandro, Schuurman, Rob, Brun-Vezinet, Francoise, Guenthard, Huldrych, Ceccherini-Silberstein, Francesca, Kaiser, Rolf, Geretti, Anna Maria, Brockmeyer, Norbert, Masquelier, Bernard

“…Plasma drug-resistant minority human immunodeficiency virus type 1 variants (DRMVs) increase the risk of virological failure to first-line non-nucleoside…”
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Learning multiple evolutionary pathways from cross-sectional data by Beerenwinkel, Niko, Rahnenführer, Jörg, Däumer, Martin, Hoffmann, Daniel, Kaiser, Rolf, Selbig, Joachim, Lengauer, Thomas

“…We introduce a mixture model of trees to describe evolutionary processes that are characterized by the ordered accumulation of permanent genetic changes. The…”
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Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment by SCHILDGEN, Oliver, SCHEWE, Carl Knud, VOGEL, Martin, DÄUMER, Martin, KAISER, Rolf, WEITNER, Lutwin, MATZ, Bertfried, ROCKSTROH, Jürgen Kurt

“…Three HIV-infected patients with chronic hepatitis B (genotype A) were switched to adefovir therapy after unsuccessful lamivudine treatment. Surprisingly,…”
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Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source by Däumer, Martin, Awerkiew, Sabine, Aragón, Saleta Sierra, Kartashev, Vladimir, Poplavskaja, Tatjana, Klein, Rolf, Sichtig, Nadine, Thiele, Bernhard, Lengauer, Thomas, Roomp, Kirsten, Pfister, Herbert, Kaiser, Rolf

“…In HIV-1, thymidine analogue mutations (TAMs) cluster in one of two groups (215Y, 41L, 210W, or 215F, 219E/Q), representing two independent mutational patterns…”
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Population and ultra‐deep sequencing for tropism determination are correlated with Trofile ES: genotypic re‐analysis of the A4001078 maraviroc study by Portsmouth, S, Valluri, S, Daeumer, M, Thiele, B, Valdez, H, Lewis, M, Craig, C, Thielen, A, James, I, Demarest, J, Heera, J

“…7‐11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK…”
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Methods for optimizing antiviral combination therapies by Beerenwinkel, Niko, Lengauer, Thomas, Däumer, Martin, Kaiser, Rolf, Walter, Hauke, Korn, Klaus, Hoffmann, Daniel, Selbig, Joachim

“…Motivation: Despite some progress with antiretroviral combination therapies, therapeutic success in the management of HIV-infected patients is limited. The…”
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Analysis of immune selection as a potential cause for the presence of cleavage site mutation 431V in treatment-naive HIV type-1 isolates by Verheyen, Jens, Schweitzer, Finja, Harrer, Ellen G, Knops, Elena, Mueller, Sandra M, Däumer, Martin, Eismann, Kathrin, Bergmann, Silke, Spriewald, Bernd M, Kaiser, Rolf, Harrer, Thomas

“…HIV type-1 (HIV-1) protease (PR) and cleavage site (CS) mutations accumulate in protease-inhibitor-resistant isolates. HIV-1 CS mutation 431V is the most…”
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Die Kurzzeitvariation der fetalen Herzfrequenz und der FIGO-CTG-Score - : Erste Erfahrungen in der Kombination dieser Überwachungsparameter by SCHIERMEIER, S, WESTHOF, G, DAUMER, M, SCHOLZ, M, HATZMANN, W

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Functional domains of the human immunodeficiency virus type 1 Nef protein are conserved among different clades in Cameroon by Ndjomou, Jean, Zekeng, Leopold, Kaptue, Lazare, Däumer, Martin, Kaiser, Rolf, Matz, Bertfried, Kupfer, Bernd

“…The Nef protein of human immunodeficiency virus type 1 (HIV-1) has multiple functional domains, is immunogenic, and contains several cytotoxic T lymphocyte…”
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LETTERS: First human immunodeficiency virus-1 group O infection in a European blood donor by Rox, J M, Eis-Huebinger, A M, Mueller, J, Vogel, M, Kaiser, R, Hanfland, P, Daeumer, M

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Epidemiology of primary drug resistance in chronically HIV-infected patients in Nordrhein-Westfalen, Germany, 2001-2005 by Oette, M, Kaiser, R, Däumer, M, Fätkenheuer, G, Rockstroh, J K, Knechten, H, Mitrenga, D, Beerenwinkel, N, Sagir, A, Pfister, H, Häussinger, D

“…Primary HIV drug resistance, characterized by mutant virus strains in untreated HIV-infected persons, is of significant epidemiological significance. Primary…”
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