Search Results - "Daemen, Mat"

Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association by Daugherty, Alan, Tall, Alan R, Daemen, Mat J.A.P, Falk, Erling, Fisher, Edward A, García-Cardeña, Guillermo, Lusis, Aldons J, Owens, A Phillip, Rosenfeld, Michael E, Virmani, Renu

“…Animal studies are a foundation for defining mechanisms of atherosclerosis and potential targets of drugs to prevent lesion development or reverse the disease…”
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Between Rho(k) and a Hard Place: The Relation Between Vessel Wall Stiffness, Endothelial Contractility, and Cardiovascular Disease by Huveneers, Stephan, Daemen, Mat J.A.P, Hordijk, Peter L

“…Vascular stiffness is a mechanical property of the vessel wall that affects blood pressure, permeability, and inflammation. As a result, vascular stiffness is…”
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Distribution of macrophage polarization markers in human atherosclerosis by Stöger, J. Lauran, Gijbels, Marion J.J, van der Velden, Saskia, Manca, Marco, van der Loos, Chris M, Biessen, Erik A.L, Daemen, Mat J.A.P, Lutgens, Esther, de Winther, Menno P.J

“…Abstract Objective Macrophages are decisive in the chronic inflammatory processes that drive atherogenesis. The purpose of this study was to explore the…”
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Cause and Mechanisms of Intracranial Atherosclerosis by Ritz, Katja, Denswil, Nerissa P, Stam, Olga C.G, van Lieshout, Johannes J, Daemen, Mat J.A.P

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Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress by CHENG, Caroline, TEMPEL, Dennie, VAN HAPEREN, Rien, VAN DER BAAN, Arjen, GROSVELD, Frank, DAEMEN, Mat J. A. P, KRAMS, Rob, DE CROM, Rini

“…Atherosclerotic lesions are predominantly observed in curved arteries and near side branches, where low or oscillatory shear stress patterns occur, suggesting…”
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MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis by Cai, Bishuang, Thorp, Edward B, Doran, Amanda C, Sansbury, Brian E, Daemen, Mat J A P, Dorweiler, Bernhard, Spite, Matthew, Fredman, Gabrielle, Tabas, Ira

“…Atherothrombotic vascular disease is often triggered by a distinct type of atherosclerotic lesion that displays features of impaired inflammation resolution,…”
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Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association by Daugherty, Alan, Tall, Alan R, Daemen, Mat J.A.P, Falk, Erling, Fisher, Edward A, García-Cardeña, Guillermo, Lusis, Aldons J, Owens, A Phillip, Rosenfeld, Michael E, Virmani, Renu

“…Animal studies are a foundation for defining mechanisms of atherosclerosis and potential targets of drugs to prevent lesion development or reverse the disease…”
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Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis by Santovito, Donato, Egea, Virginia, Bidzhekov, Kiril, Natarelli, Lucia, Mourão, André, Blanchet, Xavier, Wichapong, Kanin, Aslani, Maria, Brunßen, Coy, Horckmans, Michael, Hristov, Michael, Geerlof, Arie, Lutgens, Esther, Daemen, Mat J A P, Hackeng, Tilman, Ries, Christian, Chavakis, Triantafyllos, Morawietz, Henning, Naumann, Ronald, von Hundelshausen, Philipp, Steffens, Sabine, Duchêne, Johan, Megens, Remco T A, Sattler, Michael, Weber, Christian

“…MicroRNAs (miRNAs) are versatile regulators of gene expression with profound implications for human disease including atherosclerosis, but whether they can…”
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Assessment of middle cerebral artery diameter during hypocapnia and hypercapnia in humans using ultra-high-field MRI by Verbree, Jasper, Bronzwaer, Anne-Sophie G T, Ghariq, Eidrees, Versluis, Maarten J, Daemen, Mat J A P, van Buchem, Mark A, Dahan, Albert, van Lieshout, Johannes J, van Osch, Matthias J P

“…In the evaluation of cerebrovascular CO2 reactivity measurements, it is often assumed that the diameter of the large intracranial arteries insonated by…”
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Thin-Walled Microvessels in Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions : Relevance of Compromised Structural Integrity for Intraplaque Microvascular Leakage by SLUIMER, Judith C, KOLODGIE, Frank D, DAEMEN, Mat J. A. P, BIJNENS, Ann P. J. J, MAXFIELD, Kimberly, PACHECO, Erica, KUTYS, Bob, DUIMEL, Hans, FREDERIK, Peter M, VAN HINSBERGH, Victor W. M, VIRMANI, Renu

“…This study sought to examine the ultrastructure of microvessels in normal and atherosclerotic coronary arteries and its association with plaque phenotype…”
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Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis by Lievens, Dirk, Zernecke, Alma, Seijkens, Tom, Soehnlein, Oliver, Beckers, Linda, Munnix, Imke C.A., Wijnands, Erwin, Goossens, Pieter, van Kruchten, Roger, Thevissen, Larissa, Boon, Louis, Flavell, Richard A., Noelle, Randolph J., Gerdes, Norbert, Biessen, Erik A., Daemen, Mat J.A.P., Heemskerk, Johan W.M., Weber, Christian, Lutgens, Esther

“…CD40 ligand (CD40L), identified as a costimulatory molecule expressed on T cells, is also expressed and functional on platelets. We investigated the thrombotic…”
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Vascular Hypothesis of Alzheimer Disease: Topical Review of Mouse Models by Scheffer, Sanny, Hermkens, Dorien M.A., van der Weerd, Louise, de Vries, Helga E., Daemen, Mat J.A.P.

“…Alzheimer disease (AD) is marked by profound neurodegeneration, neuroinflammation, and cognitive decline. Pathologically, AD is characterized by the…”
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Angiotensin-Converting Enzyme and Vascular Remodeling by Heeneman, Sylvia, Sluimer, Judith C, Daemen, Mat J.A.P

“…Vascular remodeling is the result of a close interplay of changes in vascular tone and structure. In this review, the role of angiotension-converting enzyme…”
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Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel by Borén, Jan, Chapman, M John, Krauss, Ronald M, Packard, Chris J, Bentzon, Jacob F, Binder, Christoph J, Daemen, Mat J, Demer, Linda L, Hegele, Robert A, Nicholls, Stephen J, Nordestgaard, Børge G, Watts, Gerald F, Bruckert, Eric, Fazio, Sergio, Ference, Brian A, Graham, Ian, Horton, Jay D, Landmesser, Ulf, Laufs, Ulrich, Masana, Luis, Pasterkamp, Gerard, Raal, Frederick J, Ray, Kausik K, Schunkert, Heribert, Taskinen, Marja-Riitta, van de Sluis, Bart, Wiklund, Olov, Tokgozoglu, Lale, Catapano, Alberico L, Ginsberg, Henry N

“…Abstract…”
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Biomechanical factors in atherosclerosis: mechanisms and clinical implications by Kwak, Brenda R, Bäck, Magnus, Bochaton-Piallat, Marie-Luce, Caligiuri, Giuseppina, Daemen, Mat J A P, Davies, Peter F, Hoefer, Imo E, Holvoet, Paul, Jo, Hanjoong, Krams, Rob, Lehoux, Stephanie, Monaco, Claudia, Steffens, Sabine, Virmani, Renu, Weber, Christian, Wentzel, Jolanda J, Evans, Paul C

“…Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall (radial, circumferential and longitudinal forces) or on the…”
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Cathepsin cysteine proteases in cardiovascular disease by Lutgens, Suzanne P.M, Cleutjens, Kitty B.J.M, Daemen, Mat J.A.P, Heeneman, Sylvia

“…Extracellular matrix (ECM) remodeling is one of the underlying mechanisms in cardiovascular diseases. Cathepsin cysteine proteases have a central role in ECM…”
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The multi-functionality of CD40L and its receptor CD40 in atherosclerosis by Lievens, Dirk, Eijgelaar, Wouter J, Biessen, Erik A L, Daemen, Mat J A P, Lutgens, Esther

“…Disrupting the CD40-CD40L co-stimulatory pathway reduces atherosclerosis and induces a stable atherosclerotic plaque phenotype that is low in inflammation and…”
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Atherosclerotic Plaque Destabilization: Mechanisms, Models, and Therapeutic Strategies by Silvestre-Roig, Carlos, de Winther, Menno P, Weber, Christian, Daemen, Mat J, Lutgens, Esther, Soehnlein, Oliver

“…Understanding the pathophysiology of atherogenesis and the progression of atherosclerosis have been major goals of cardiovascular research during the previous…”
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Hypoxia in atherosclerosis and inflammation by Marsch, Elke, Sluimer, Judith C., Daemen, Mat J.A.P.

“…Hypoxia triggers various cellular processes, both in physiological and pathological conditions, and has recently also been implicated in atherosclerosis. This…”
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Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis by Sluimer, Judith C, Daemen, Mat J

“…The clinical complications of atherosclerosis are caused by thrombus formation, which in turn results from rupture of an unstable atherosclerotic plaque. The…”
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